home > Gene Annotation List

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NCBI IDProteinIDLocusTagProductIDCazyIDOrthGroupIDSGD IDidentevalAnnotationASpGD IDidentEvalAnnotation
GBC11729.1g23192.t1RIR_0073400retrotransposable element-OG0000004YIL082W-A40.874.00E-88"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547036.364.00E-74Predicted gypsy transposon-related ORF
GBC11730.1g23193.t1RIR_0073500hypothetical protein-OG0000066--------
GBC11731.1g23194.t1RIR_0073600gag-pol fusion protein-OG0000138--------
GBC11732.1JEMT01018046.1_cds_EXX67055.1_12977RIR_0073610JEMT01018046.1_cds_EXX67055.1_12977----------
GBC11739.1g23201.t1RIR_0074300transposase domain-containing protein-OG0000002--------
GBC11741.1g23202.t1RIR_0074400serine/threonine protein kinase-OG0000000YOL113W23.881.00E-15"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN1015328.322.00E-17Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC11742.1g23203.t1RIR_0074500vacuolar transmembrane protein; tms1p-OG0000836YDR105C40.356.00E-104"Vacuolar membrane protein of unknown function; is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance"AN1124441.612.00E-112"Ortholog of S. cerevisiae : TMS1, A. fumigatus Af293 : Afu2g13400, A. niger CBS 513.88 : An02g02270, A. oryzae RIB40 : AO090026000317 and Aspergillus wentii : Aspwe1_0044592"
GBC11743.1g23204.t1RIR_0074600serine/threonine protein kinase--YPL140C24.022.00E-15"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"AN1015324.532.00E-15Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC11744.1g23205.t1RIR_0074700hypothetical protein-OG0000172--------
GBC11745.1g23206.t1RIR_0074800retrotransposable element-OG0000004YIL082W-A41.328.00E-101"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547036.751.00E-93Predicted gypsy transposon-related ORF
GBC11746.1g23207.t1RIR_0074900retrotransposable element-OG0000004YIL082W-A27.326.00E-30"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN1064931.22.00E-31"Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process"
GBC11747.1g23208.t1RIR_0075000serine/threonine protein kinase----------
GBC11749.1g23209.t1RIR_0075100serine/threonine protein kinase-OG0000000YDR523C283.00E-18Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by themAN581529.611.00E-19Aurora protein serine/threonine kinase
GBC11750.1g23210.t1RIR_0075200hypothetical protein----------
GBC11751.1g23211.t1RIR_0075300umta methyltransferase family protein-OG0000025----AN587430.774.00E-16Putative LaeA-like methyltransferase
GBC11752.1g23212.t1RIR_0075400Insulysin-OG0000752YLR389C42.090Metalloprotease; involved in N-terminal processing of pro-a-factor to the mature form; expressed in both haploids and diploids; member of the insulin-degrading enzyme family; homolog Axl1p is also involved in processing of pro-a-factorAN804448.950Ortholog(s) have metalloendopeptidase activity
GBC11753.1g23213.t1RIR_0075500ring finger protein-OG0000643----AN368926.483.00E-17Ortholog(s) have site of double-strand break localization
GBC11754.1g23214.t1RIR_0075600ring/u-box-OG0000311----AN368928.271.00E-16Ortholog(s) have site of double-strand break localization
GBC11755.1g23215.t1RIR_0075700ring/u-box-OG0000311----AN368925.77.00E-12Ortholog(s) have site of double-strand break localization
GBC11756.1g23216.t1RIR_0075800hypothetical protein----------
GBC11757.1g23217.t1RIR_0075900hypothetical protein----------
GBC11759.1g23219.t1RIR_0076100hypothetical protein-OG0000002--------
GBC11760.1JEMT01024771.1_cds_EXX62299.1_17728RIR_0076110JEMT01024771.1_cds_EXX62299.1_17728----------
GBC11763.1g23222.t1RIR_0076400transposase domain-containing protein-OG0000002--------
GBC11764.1g23223.t1RIR_0076500zn-finger domain-containing protein-OG0000026--------
GBC11767.1g23226.t1RIR_0076800cytochrome p450 monooxygenase-OG0000114YMR015C24.354.00E-12C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugsAN1038926.091.00E-27Putative cytochrome P450
GBC11768.1g23227.t1RIR_0076900Cytochrome P450 monooxygenase-OG0000007YDR402C26.456.00E-28"N-formyltyrosine oxidase; sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s"AN683527.184.00E-26Putative cytochrome P450; expression upregulated after exposure to farnesol
GBC11769.1g23228.t1RIR_0077000cytochrome p450 monooxygenase-OG0000114YHR007C27.483.00E-15"Lanosterol 14-alpha-demethylase; catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p"AN1038927.811.00E-27Putative cytochrome P450
GBC11770.1JEMT01028497.1_cds_EXX54352.1_25680RIR_0077010JEMT01028497.1_cds_EXX54352.1_25680----------
GBC11771.1JEMT01028497.1_cds_EXX54353.1_25681RIR_0077020JEMT01028497.1_cds_EXX54353.1_25681-OG0000034--------
GBC11773.1g23230.t1RIR_0077200Telomerase reverse transcriptase-OG0001797YLR318W25.153.00E-12"Reverse transcriptase subunit of the telomerase holoenzyme; essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia"AN375329.736.00E-51"Ortholog(s) have telomerase RNA binding, telomerase RNA reverse transcriptase activity and role in DNA strand elongation, telomere maintenance via telomerase"
GBC11776.1g23233.t1RIR_0077500hypothetical protein-OG0000034--------
GBC11779.1JEMT01027386.1_cds_EXX57414.1_22617RIR_0077710JEMT01027386.1_cds_EXX57414.1_22617-OG0000034--------
GBC11782.1g23238.t1RIR_0078000hypothetical protein-OG0000026--------
GBC11783.1g23239.t1RIR_0078100zinc finger bed domain-containing protein----------
GBC11785.1g23241.t1RIR_0078300reverse transcriptase-OG0000001----AN036822.072.00E-14"Has domain(s) with predicted RNA binding, RNA-DNA hybrid ribonuclease activity, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in RNA-dependent DNA biosynthetic process"
GBC11787.1g23243.t1RIR_0078500cellular nucleic acid-binding protein-OG0000639--------
GBC11789.1JEMT01025019.1_cds_EXX61797.1_18229RIR_0078610JEMT01025019.1_cds_EXX61797.1_18229----------
GBC11791.1g23246.t1RIR_0078800protein far1-related sequence 5-like-OG0000030--------
GBC11795.1g23249.t1RIR_0079100Cytochrome P450 monooxygenase-OG0000007YDR402C28.351.00E-32"N-formyltyrosine oxidase; sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s"AN270624.573.00E-28Putative cytochrome P450
GBC11796.1g23250.t1RIR_0079200hypothetical protein----------
GBC11797.1g23251.t1RIR_0079300Shikimate O-hydroxycinnamoyltransferase-OG0001113----AN254820.927.00E-18Putative acyltransferase; required for emericellamide biosynthesis; emericellamide (eas) biosynthetic gene cluster member
GBC11799.1g23253.t1RIR_0079500hypothetical protein-OG0000034--------
GBC11802.1JEMT01018270.1_cds_EXX66837.1_13192RIR_0079710JEMT01018270.1_cds_EXX66837.1_13192----------
GBC11803.1g23256.t1RIR_0079800hypothetical protein----------
GBC11804.1g23257.t1RIR_0079900gag-pol fusion protein-OG0000004YGR109W-B42.336.00E-93"Chr VII from 707610-708459,708461-712254, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547041.191.00E-96Predicted gypsy transposon-related ORF
GBC11805.1g23258.t1RIR_0080000retrotransposable element-OG0000004YGR109W-B27.646.00E-30"Chr VII from 707610-708459,708461-712254, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN1064926.831.00E-30"Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process"
GBC11806.1g23259.t1RIR_0080100hypothetical protein----------
GBC11811.1g23263.t1RIR_0080500hypothetical protein-OG0000366--------
GBC11814.1g23266.t1RIR_0080800hypothetical protein-OG0000004--------
GBC11816.1g23268.t1RIR_0081000gastrula zinc finger protein xlcgf46.1-OG0000287--------
GBC11818.1g23270.t1RIR_0081200hypothetical protein-OG0000026--------
GBC11821.1g23273.t1RIR_0081500RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC11823.1g23275.t1RIR_0081700hypothetical protein----------
GBC11824.1g23276.t1RIR_0081800gag-pol fusion protein-OG0000066--------
GBC11825.1g23277.t1RIR_0081900retrotransposable element-OG0000004YIL082W-A40.985.00E-106"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547041.43.00E-104Predicted gypsy transposon-related ORF
GBC11826.1g23278.t1RIR_0082000retrotransposable element-OG0000004YGR109W-B27.864.00E-35"Chr VII from 707610-708459,708461-712254, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN2670296.00E-33"Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process"
GBC11827.1g23279.t1RIR_0082100zinc finger bed domain-containing protein-OG0000008----AN1107427.944.00E-17Predicted hAT transposon-related ORF
GBC11828.1g23280.t1RIR_0082200zinc finger bed domain-containing protein-OG0000008--------
GBC11829.1Tis13_68582RIR_0082210Tis13_68582-OG0000052--------
GBC11830.1g23281.t1RIR_0082300hypothetical protein-OG0000052--------
GBC11838.1g23287.t1RIR_0082900hypothetical protein-OG0000034--------
GBC11841.1g23289.t1RIR_0083100Shikimate O-hydroxycinnamoyltransferase-OG0001113----AN254820.838.00E-19Putative acyltransferase; required for emericellamide biosynthesis; emericellamide (eas) biosynthetic gene cluster member
GBC11842.1g23290.t1RIR_0083200hypothetical protein----------
GBC11843.1g23291.t1RIR_0083300Cytochrome P450 monooxygenase-OG0000007YDR402C28.351.00E-32"N-formyltyrosine oxidase; sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s"AN270624.573.00E-28Putative cytochrome P450
GBC11847.1g23295.t1RIR_0083700hypothetical protein-OG0000034--------
GBC11848.1g23296.t1RIR_0083800hypothetical protein-OG0000034--------
GBC11849.1g23297.t1RIR_0083900cytochrome p450 monooxygenase-OG0000114YHR007C24.355.00E-23"Lanosterol 14-alpha-demethylase; catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p"AN1038927.551.00E-26Putative cytochrome P450
GBC11850.1g23298.t1RIR_0084000Cytochrome P450 monooxygenase-OG0000007YDR402C26.456.00E-28"N-formyltyrosine oxidase; sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s"AN683527.184.00E-26Putative cytochrome P450; expression upregulated after exposure to farnesol
GBC11851.1g23299.t1RIR_0084100cytochrome p450 monooxygenase-OG0000114YMR015C24.354.00E-12C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugsAN1038926.091.00E-27Putative cytochrome P450
GBC11853.1Tis13_87760RIR_0084120Tis13_87760----------
GBC11854.1g23300.t1RIR_0084200kelch-like protein 17-OG0000006--------
GBC11855.1g23301.t1RIR_0084300extracellular serine-rich protein-OG0001926--------
GBC11856.1g23302.t1RIR_0084400U3 small nucleolar RNA-associated protein 7-OG0002335YER082C48.175.00E-172Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNAAN626549.45.00E-176"Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more"
GBC11857.1g23303.t1RIR_0084500putative Intron-binding protein aquarius-OG0004033YMR080C30.142.00E-25ATP-dependent RNA helicase of the SFI superfamily; involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; binds to the small ribosomal subunit via an interaction with Rps26; forms cytoplasmic foci upon DNA replication stressAN701446.880"Has domain(s) with predicted pre-mRNA intronic binding activity, role in mRNA splicing, via spliceosome and spliceosomal complex localization"
GBC11858.1g23304.t1RIR_0084600"Phosphatidylinositol glycan, class C"-OG0002284YPL076W265.00E-16Protein involved in the synthesis of GlcNAc-PI; GlcNAc-PI is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; GlcNAc-PI stands for N-acetylglucosaminyl phosphatidylinositolAN1123248.452.00E-44"Has domain(s) with predicted phosphatidylinositol N-acetylglucosaminyltransferase activity, role in GPI anchor biosynthetic process and integral component of membrane localization"
GBC11859.1g23305.t1RIR_0084700hypothetical protein----------
GBC11860.1Tis13_348023RIR_0084710Tis13_348023----------
GBC11861.1g23306.t1RIR_0084800hypothetical protein----------
GBC11862.1g23307.t1RIR_0084900calmodulin-dependent protein kinase-OG0000000YAR019C22.72.00E-15Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN438526.452.00E-15"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC11863.1g23308.t1RIR_0085000serine/threonine protein kinase-OG0000000YDR523C25.781.00E-13Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by themAN1015323.674.00E-12Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC11864.1g23309.t1RIR_0085100hypothetical protein----------
GBC11867.1g23311.t1RIR_0085300hypothetical protein----------
GBC11868.1g23312.t1RIR_0085400Ubiquinone biosynthesis protein COQ9-OG0003027YLR201C26.095.00E-16Protein required for ubiquinone biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; ubiquinone is also known as coenzyme QAN373831.962.00E-36Ortholog(s) have role in ubiquinone biosynthetic process and mitochondrion localization
GBC11869.1g23313.t1RIR_0085500ATP-dependent helicase-OG0001958--------
GBC11870.1g23314.t1RIR_0085600cytochrome p450 monooxygenase-OG0000007YMR015C31.875.00E-17C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugsAN788127.521.00E-17Putative cytochrome P450; predicted secondary metabolism gene cluster member
GBC11871.1g23314.t2RIR_0085600cytochrome p450 monooxygenase-OG0000007YMR015C31.875.00E-17C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugsAN788127.656.00E-18Putative cytochrome P450; predicted secondary metabolism gene cluster member
GBC11872.1Tis13_3974RIR_0085610Tis13_3974----------
GBC11873.1g23315.t1RIR_0085700hypothetical protein----------
GBC11874.1Tis13_344416RIR_0085710Tis13_344416----------
GBC11875.1g23316.t1RIR_0085800hypothetical protein----------
GBC11877.1g23318.t1RIR_0086000hypothetical protein----------
GBC11878.1g23319.t1RIR_0086100btb/poz domain-containing protein 9-OG0000006--------
GBC11880.1g23320.t1RIR_0086200btb/poz domain-containing protein 9-OG0000006--------
GBC11882.1Tis13_26173RIR_0086220Tis13_26173----------
GBC11883.1g23321.t1RIR_0086300hypothetical protein----------
GBC11884.1g23322.t1RIR_0086400jerky protein homolog-like-OG0001396--------
GBC11885.1g23323.t1RIR_0086500hypothetical protein----------
GBC11886.1g23324.t1RIR_0086600sequence orphan-OG0000536--------
GBC11887.1Tis13_349089RIR_0086610Tis13_349089----------
GBC11888.1g23325.t1RIR_0086700pro-resilin isoform x1----------
GBC11889.1g23326.t1RIR_0086800pentatricopeptide repeat-containing protein----------
GBC11890.1g23327.t1RIR_0086900hypothetical protein-OG0003653--------
GBC11891.1g23327.t2RIR_0086900hypothetical protein-OG0003653--------
GBC11892.1g23328.t1RIR_0087000endonuclease/exonuclease/phosphatase family-OG0003263--------
GBC11893.1g23329.t2RIR_0087100piso0_002032-OG0004288--------
GBC11894.1g23329.t1RIR_0087100piso0_002032-OG0004288--------
GBC11895.1g23330.t1RIR_0087200ino eighty subunit 2-OG0003601----AN626042.375.00E-13Has domain(s) with predicted Ino80 complex localization
GBC11896.1g23331.t1RIR_0087300hypothetical protein-OG0000867--------
GBC11897.1g23331.t2RIR_0087300hypothetical protein-OG0000867--------
GBC11898.1g23332.t1RIR_0087400hypothetical protein-OG0005553--------
GBC11899.1g23333.t1RIR_0087500Inosine triphosphate pyrophosphatase-OG0001833YJR069C47.184.00E-45"Nucleoside triphosphate pyrophosphohydrolase; active against a wide range of substrates including ITP, dITP and XTP; mediates exclusion of noncanonical purines and pyrimidines from deoxyribonucleoside triphosphate pools; functions together with YJL055W to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA without affecting uptake or incorporation of uracil into RNA; protein abundance increases in response to DNA replication stress"AN8861603.00E-73"Ortholog(s) have GTP diphosphatase activity, ITP diphosphatase activity, UTP diphosphatase activity, XTP diphosphatase activity, dATP pyrophosphohydrolase activity and dCTP diphosphatase activity, more"
GBC11900.1g23334.t1RIR_0087600mcm domain-containing protein 2-OG0005611--------
GBC11901.1g23335.t1RIR_0087700Mitochondrial import receptor subunit TOM22-OG0002662----AN110532.212.00E-12"Ortholog(s) have mitochondrion targeting sequence binding, protein transmembrane transporter activity"
GBC11902.1g23336.t1RIR_0087800Transcription initiation factor TFIIIB subunit-OG0002186YGR246C34.171.00E-103"TFIIIB B-related factor; one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB; mutations in human homolog are associated with autosomal recessive cerebellar-facial-dental syndrome"AN311638.874.00E-104"Ortholog(s) have RNA polymerase III type 3 promoter sequence-specific DNA binding, TFIIIB-type transcription factor activity and role in positive regulation of transcription by RNA polymerase III"
GBC11903.1g23337.t1RIR_0087900DNA-binding protein hgh1-OG0003160YGR187C39.076.00E-73Nonessential protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16); relative distribution to the nucleus increases upon DNA replication stressAN940943.426.00E-70Putative ortholog of S. cerevisiae Hgh1p; expression reduced after exposure to farnesol
GBC11904.1g23338.t1RIR_0088000cdk5 and abl1 enzyme substrate 1-like-OG0003269--------
GBC11905.1g23339.t1RIR_0088100ubp5 interacting protein ftp10-OG0002873----AN880944.586.00E-110"Ortholog of A. fumigatus Af293 : Afu5g09520, A. niger CBS 513.88 : An07g03420, A. oryzae RIB40 : AO090020000579, Aspergillus wentii : Aspwe1_0023802 and Aspergillus sydowii : Aspsy1_0135706"
GBC11906.1g23340.t1RIR_0088200"Tyrosyl-tRNA synthetase, cytoplasmic"-OG0000571YGR185C59.62.00E-148Cytoplasmic tyrosyl-tRNA synthetase; required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies; protein abundance increases in response to DNA replication stressAN005753.961.00E-119"Has domain(s) with predicted ATP binding, aminoacyl-tRNA ligase activity, tyrosine-tRNA ligase activity, role in tRNA aminoacylation for protein translation, tyrosyl-tRNA aminoacylation and cytoplasm localization"
GBC11907.1g23341.t1RIR_0088300Coatomer subunit alpha-OG0001724YDL145C47.280Alpha subunit of COPI vesicle coatomer complex; complex surrounds transport vesicles in the early secretory pathwayAN302657.840Alpha-COP coatamer-related protein involved in the establishment and maintenance of polarized growth; temperature sensitive mutants defective in nuclear division at the restrictive temperature
GBC11908.1g23342.t1RIR_0088400GTPase MTG2-OG0002049YHR168W33.088.00E-16"Putative GTPase; member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly"AN088934.965.00E-17"Ortholog(s) have ribosome binding activity, role in cytoplasmic translation and extrinsic component of membrane, mitochondrial inner membrane localization"
GBC11909.1g23343.t2RIR_0088500u4/u6.u5 tri-snrnp-associated protein 3-OG0004047----AN1083552.082.00E-11Has domain(s) with predicted role in RNA splicing
GBC11910.1g23343.t1RIR_0088500u4/u6.u5 tri-snrnp-associated protein 3-OG0004047----AN1083552.082.00E-11Has domain(s) with predicted role in RNA splicing
GBC11911.1g23344.t1RIR_0088600Acetyl-CoA C-acetyltransferase-OG0000651YPL028W51.614.00E-44"Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis"AN1051251.797.00E-54Putative mitochondrial ketoacyl-CoA thiolase with a role in fatty acid beta-oxidation
GBC11912.1g23345.t1RIR_0088700Acetyl-CoA C-acetyltransferase-OG0000651YPL028W51.052.00E-72"Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis"AN1051254.858.00E-90Putative mitochondrial ketoacyl-CoA thiolase with a role in fatty acid beta-oxidation
GBC11913.1g23346.t1RIR_0088800hypothetical protein----------
GBC11914.1g23347.t1RIR_0088900morphogenesis protein-OG0004373----AN010535.194.00E-13Has domain(s) with predicted translation initiation factor activity and role in translational initiation
GBC11915.1g23348.t1RIR_0089000WD repeat-containing protein 22-OG0004682YMR116C24.594.00E-12G-protein beta subunit and guanine dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; regulates P-body formation induced by replication stress; represses Gcn4p in the absence of amino acid starvationAN846826.718.00E-16"Ortholog of A. nidulans FGSC A4 : AN2021, A. fumigatus Af293 : Afu7g00550 and A. niger CBS 513.88 : An15g05630, An11g03460, An11g07530, An04g03850, An09g00640"
GBC11916.1g23349.t1RIR_0089100importin alpha subunit-OG0000433YNL189W38.724.00E-115"Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation"AN214242.576.00E-133"Karyopherin (importin) alpha, involved in protein import into nucleus"
GBC11917.1g23350.t2RIR_0089200hypothetical protein----------
GBC11918.1g23350.t1RIR_0089200hypothetical protein----------
GBC11920.1g23352.t1RIR_0089400protein far-red impaired response 1-OG0000030--------
GBC11922.1g23354.t1RIR_0089600AP-3 complex subunit sigma-OG0000250YJL024C34.463.00E-27Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stressAN551941.341.00E-41"Ortholog(s) have role in Golgi to vacuole transport, pathogenesis, protein targeting to vacuole and AP-3 adaptor complex localization"
GBC11923.1g23355.t1RIR_0089700Ribosomal 40S subunit protein S7-OG0000896YOR096W59.881.00E-70"Protein component of the small (40S) ribosomal subunit; interacts with Kti11p; deletion causes hypersensitivity to zymocin; homologous to mammalian ribosomal protein S7, no bacterial homolog; RPS7A has a paralog, RPS7B, that arose from the whole genome duplication"AN491657.874.00E-69"Ortholog(s) have role in ribosome biogenesis and cell surface, small-subunit processome localization"
GBC11924.1g23356.t1RIR_0089800S-adenosylmethionine decarboxylase-OG0000995YOL052C34.281.00E-59S-adenosylmethionine decarboxylase; required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobicallyAN823138.637.00E-90Putative S-adenosylmethionine decarboxylase with a predicted role in arginine metabolism
GBC11925.1g23357.t1RIR_0089900ATP-dependent NAD(P)H-hydrate dehydratase-OG0002180YKL151C43.523.00E-79"NADHX dehydratase; converts (S)-NADHX to NADH in an ATP-dependent manner; homologous to Carkd in mammals, and the C-terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress"AN599441.677.00E-91Ortholog(s) have ATP-dependent NAD(P)H-hydrate dehydratase activity and role in nicotinamide nucleotide metabolic process
GBC11926.1g23358.t1RIR_0090000Notchless protein homolog-OG0000517YCR072C50.291.00E-177"WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus"AN1005849.92.00E-173"Ortholog(s) have role in cellular response to drug, ribosomal large subunit assembly and nucleolus localization"
GBC11927.1g23359.t1RIR_0090100"chloride channel protein, nucleotide-sensitive,"-OG0002937--------
GBC11928.1g23360.t2RIR_0090200saga complex subunit spt20-OG0002266--------
GBC11929.1g23360.t1RIR_0090200saga complex subunit spt20-OG0002266--------
GBC11930.1g23361.t1RIR_0090300zinc finger bed domain-containing protein-OG0000008----AN11074244.00E-12Predicted hAT transposon-related ORF
GBC11931.1g23362.t3RIR_0090400lysine-specific demethylase 3-OG0003491--------
GBC11932.1g23362.t1RIR_0090400lysine-specific demethylase 3-OG0003491--------
GBC11933.1g23362.t2RIR_0090400lysine-specific demethylase 3-OG0003491--------
GBC11934.1g23363.t1RIR_0090500Enolase-phosphatase E1-OG0004074YEL038W34.274.00E-35Protein with sequence similarity to acireductone synthases; involved in methionine salvage; found in both the cytoplasm and nucleus----
GBC11935.1g23364.t1RIR_0090600mitochondrial ribosomal protein subunit mrp21-OG0004208--------
GBC11936.1g23365.t1RIR_0090700vesicle coat complex subunit zeta-OG0002216YPL010W38.622.00E-43Zeta subunit of the coatomer complex (COPI); COPI coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ERAN608042.643.00E-48"Ortholog(s) have role in retrograde vesicle-mediated transport, Golgi to ER and COPI vesicle coat localization"
GBC11937.1g23366.t1RIR_0090800Very-long-chain enoyl-CoA reductase-OG0002672YDL015C35.533.00E-44"Enoyl reductase; catalyzes the last step in each cycle of very long chain fatty acid elongation; localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions; coimmunoprecipitates with elongases Fen1p and Sur4p; protein increases in abundance and relative distribution to ER foci increases upon DNA replication stress"AN196838.562.00E-65"Ortholog(s) have oxidoreductase activity, role in very long-chain fatty acid metabolic process and endoplasmic reticulum membrane localization"
GBC11938.1g23367.t1RIR_0090900Enolase-phosphatase E1-OG0002306YKR081C38.952.00E-63Essential protein involved in rRNA maturation and ribosomal assembly; involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particlesAN1020032.923.00E-47Ribosome assembly factor; component of the Rpf2-Rrs1 complex; ortholog of S. cerevisiae Rpf2p; expression reduced after exposure to farnesol
GBC11939.1g23368.t2RIR_0091000hypothetical protein----------
GBC11940.1g23368.t1RIR_0091000hypothetical protein----------
GBC11941.1g23369.t1RIR_0091100mitochondrial inner membrane protein-OG0004609--------
GBC11942.1g23370.t1RIR_0091200hypothetical protein----------
GBC11943.1g23371.t1RIR_0091300Replication factor A2-OG0002519YNL312W28.043.00E-18"Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; in concert with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication s"AN058233.569.00E-20"Ortholog(s) have double-stranded DNA binding, sequence-specific DNA binding, single-stranded DNA binding activity"
GBC11944.1g23372.t1RIR_0091400hypothetical protein----------
GBC11945.1g23373.t1RIR_0091500Vacuolar protein sorting-associated protein 45-OG0002578YGL095C41.073.00E-142Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartmentAN653160.440Putative Sec1p-like protein with a predicted role in vacuolar protein sorting
GBC11946.1g23374.t2RIR_0091600Large subunit ribosomal protein L49-OG0002875----AN290628.817.00E-12"Has domain(s) with predicted structural constituent of ribosome activity, role in translation and ribosome localization"
GBC11947.1g23374.t1RIR_0091600Large subunit ribosomal protein L49-OG0002875----AN290628.817.00E-12"Has domain(s) with predicted structural constituent of ribosome activity, role in translation and ribosome localization"
GBC11948.1g23375.t1RIR_0091700Ribosome biogenesis protein NSA1-OG0003504YGL111W30.094.00E-14Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis----
GBC11949.1g23376.t1RIR_0091800conserved eukaryotic protein-OG0005828--------
GBC11950.1g23377.t1RIR_0091900endoplasmic reticulum dnaj domain protein erj5-OG0002051YFR041C28.881.00E-26Type I membrane protein with a J domain; required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein responseAN577041.99.00E-45"Ortholog of A. fumigatus Af293 : Afu6g06610, A. niger CBS 513.88 : An18g06470, A. oryzae RIB40 : AO090003000036, Aspergillus wentii : Aspwe1_0038379 and Aspergillus sydowii : Aspsy1_0149748"
GBC11951.1g23378.t2RIR_0092000histone demethylase jmj1-OG0001793----AN293330.874.00E-35"Ortholog of A. fumigatus Af293 : Afu3g08170, A. niger CBS 513.88 : An02g11690, A. oryzae RIB40 : AO090005001460, Aspergillus wentii : Aspwe1_0113955 and Aspergillus sydowii : Aspsy1_0029366"
GBC11952.1g23378.t1RIR_0092000histone demethylase jmj1-OG0001793----AN293331.494.00E-31"Ortholog of A. fumigatus Af293 : Afu3g08170, A. niger CBS 513.88 : An02g11690, A. oryzae RIB40 : AO090005001460, Aspergillus wentii : Aspwe1_0113955 and Aspergillus sydowii : Aspsy1_0029366"
GBC11953.1g23379.t1RIR_0092100hypothetical protein----------
GBC11954.1g23380.t1RIR_0092200zinc finger ccch domain-containing protein-OG0000699----AN153742.994.00E-23"Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts and NURS complex, nuclear body, nuclear chromatin localization"
GBC11955.1g23381.t1RIR_0092300hypothetical protein----------
GBC11956.1g23382.t1RIR_0092400zinc finger bed domain-containing protein----------
GBC11957.1g23383.t1RIR_0092500hypothetical protein-OG0001268--------
GBC11959.1g23385.t1RIR_0092700protein far-red impaired response 1 isoform x3-OG0000030--------
GBC11960.1JEMT01017978.1_cds_EXX67143.1_12883RIR_0092710JEMT01017978.1_cds_EXX67143.1_12883----------
GBC11961.1g23386.t1RIR_0092800hypothetical protein----------
GBC11962.1g23387.t1RIR_0092900white collar 2 protein-OG0000499YMR136W40.794.00E-14Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucineAN360742.571.00E-17"Putative zinc-finger transcription factor involved in blue-light responsive differentiation; interacts with VeA, FphA, and LreA; similar to N. crassa blue-light-sensing component WC-2"
GBC11963.1g23387.t2RIR_0092900white collar 2 protein-OG0000499YMR136W40.793.00E-14Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucineAN360742.571.00E-17"Putative zinc-finger transcription factor involved in blue-light responsive differentiation; interacts with VeA, FphA, and LreA; similar to N. crassa blue-light-sensing component WC-2"
GBC11965.1g23388.t1RIR_0093000ap-1-like transcription factor yap1-OG0000130--------
GBC11971.1g23392.t1RIR_0093400CENP-b protein 1-OG0000010----AN871731.032.00E-41"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC11974.1g23395.t1RIR_0093700transposase domain-containing protein-OG0000002--------
GBC11976.1g23397.t1RIR_0093900transposable element tc3 transposase-OG0000005--------
GBC11977.1g23398.t1RIR_0094000hypothetical protein----------
GBC11978.1g23399.t1RIR_0094100hypothetical protein----------
GBC11979.1g23400.t1RIR_0094200hypothetical protein----------
GBC11980.1g23401.t1RIR_0094300transcription initiation factor iif subunit-OG0003050YGR186W30.113.00E-25TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74----
GBC11981.1g23402.t1RIR_0094400Ubiquitin C-OG0001070YLL039C96.495.00E-154"Ubiquitin; becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats; protein abundance increases in response to DNA replication stress"AN200096.935.00E-155"Polyubiquitin, contains four head to tail repeats of ubiqiutin; transcript upregulated in response to camptothecin"
GBC11982.1g23403.t1RIR_0094500Ribosomal 40S subunit protein S17-OG0001160YML024W68.254.00E-56"Ribosomal protein 51 (rp51) of the small (40s) subunit; homologous to mammalian ribosomal protein S17, no bacterial homolog; RPS17A has a paralog, RPS17B, that arose from the whole genome duplication"AN597969.063.00E-62Ortholog(s) have role in ribosomal small subunit assembly
GBC11983.1g23404.t1RIR_0094600mitochondrial iron sulfur cluster assembly-OG0003131YER048W-A38.271.00E-17"Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis; exclusive to eukaryotes, implicated as eukaryotic supplement to the bacterium-derived Fe-S cluster (ISC) assembly apparatus; involved in regulation of iron metabolism; member of the LYR protein family"AN1058443.847.00E-17"Ortholog(s) have cysteine desulfurase activity, role in iron-sulfur cluster assembly and L-cysteine desulfurase complex, extrinsic component of mitochondrial inner membrane, mitochondrial matrix localization"
GBC11984.1g23405.t1RIR_0094700Protein transport protein SEC61 subunit gamma-OG0001558YDR086C46.978.00E-21"Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p"AN458964.297.00E-32"Putative translocon, beta subunit; ortholog of S. cerevisiae Sss1p"
GBC11985.1g23406.t2RIR_0094800n-acetyltransferase-OG0003205--------
GBC11986.1g23406.t1RIR_0094800n-acetyltransferase-OG0003205--------
GBC11987.1g23407.t1RIR_0094900CENP-b protein 1-OG0000010--------
GBC11988.1g23408.t1RIR_0095000putative zinc finger domain-containing protein-OG0000011----AN200952.384.00E-17"Ortholog(s) have role in conidiophore development, conidium formation, hyphal growth"
GBC11989.1g23409.t1RIR_0095100Ribonuclease P/MRP protein subunit POP5-OG0002229YAL033W31.822.00E-12"Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs"AN243727.124.00E-15"Ortholog(s) have RNA binding, ribonuclease MRP activity, ribonuclease P activity"
GBC11990.1g23410.t1RIR_0095200hypothetical protein-OG0000052--------
GBC11992.1JEMT01027458.1_cds_EXX57034.1_22999RIR_0095310JEMT01027458.1_cds_EXX57034.1_22999----------
GBC11993.1JEMT01027458.1_cds_EXX57033.1_22998RIR_0095320JEMT01027458.1_cds_EXX57033.1_22998----------
GBC11994.1g23412.t1RIR_0095400hypothetical protein----------
GBC11995.1g23413.t1RIR_0095500hypothetical protein----------
GBC11996.1g23414.t1RIR_0095600reverse transcriptase-OG0000001--------
GBC11999.1g23417.t1RIR_0095900zinc finger bed domain-containing protein----------
GBC12000.1JEMT01018901.1_cds_EXX66419.1_13609RIR_0095910JEMT01018901.1_cds_EXX66419.1_13609----------
GBC12002.1g23418.t1RIR_0096000transposable element tc3 transposase-OG0001015--------
GBC12003.1g23419.t1RIR_0096100zinc finger mym-type protein 2-like----------
GBC12006.1g23422.t1RIR_0096400hypothetical protein----------
GBC12007.1g23423.t1RIR_0096500hypothetical protein----------
GBC12009.1g23424.t1RIR_0096600histone promoter control protein hip4-OG0003429--------
GBC12010.1g23425.t1RIR_0096700Survival of motor neuron-related-splicing factor-OG0003999----AN1094535.714.00E-11"Ortholog of A. fumigatus Af293 : Afu6g09950, A. niger CBS 513.88 : An11g08010, A. oryzae RIB40 : AO090001000628, Aspergillus wentii : Aspwe1_0121304 and Aspergillus sydowii : Aspsy1_0058487"
GBC12013.1JEMT01017484.1_cds_EXX67908.1_12119RIR_0096910JEMT01017484.1_cds_EXX67908.1_12119----------
GBC12017.1g23431.t1RIR_0097300ATP-dependent DNA helicase pif1-OG0000037--------
GBC12020.1g23434.t1RIR_0097600CENP-b protein 1-OG0000010----AN615627.341.00E-15"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC12023.1g23437.t1RIR_0097900zinc finger bed domain-containing protein-OG0000008--------
GBC12024.1g23438.t2RIR_0098000Ribonuclease H2 subunit A-OG0002218YNL072W40.164.00E-41Ribonuclease H2 catalytic subunit; removes RNA primers during Okazaki fragment synthesis and errant ribonucleotides misincorporated during DNA replication; role in ribonucleotide excision repair; homolog of RNAse HI; related to human AGS4 which causes Aicardi-Goutieres syndromeAN511435.997.00E-38Ortholog(s) have RNA-DNA hybrid ribonuclease activity and role in ribonucleotide excision repair
GBC12025.1g23438.t1RIR_0098000Ribonuclease H2 subunit A-OG0002218YNL072W36.451.00E-25Ribonuclease H2 catalytic subunit; removes RNA primers during Okazaki fragment synthesis and errant ribonucleotides misincorporated during DNA replication; role in ribonucleotide excision repair; homolog of RNAse HI; related to human AGS4 which causes Aicardi-Goutieres syndromeAN511433.585.00E-26Ortholog(s) have RNA-DNA hybrid ribonuclease activity and role in ribonucleotide excision repair
GBC12026.1g23439.t2RIR_0098100Large subunit GTPase 1-OG0000907YGL099W42.188.00E-111Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasmAN226359.511.00E-84"Ortholog(s) have role in ascospore formation, conjugation with cellular fusion, ribosomal large subunit assembly, ribosomal subunit export from nucleus and cytosolic large ribosomal subunit localization"
GBC12027.1g23439.t1RIR_0098100Large subunit GTPase 1-OG0000907YGL099W39.63.00E-95Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasmAN226354.019.00E-85"Ortholog(s) have role in ascospore formation, conjugation with cellular fusion, ribosomal large subunit assembly, ribosomal subunit export from nucleus and cytosolic large ribosomal subunit localization"
GBC12028.1g23440.t1RIR_0098200dnaj-like n-terminal domain-containing protein-OG0000067----AN1168726.671.00E-14Ortholog(s) have mitochondrion localization
GBC12029.1g23440.t2RIR_0098200dnaj-like n-terminal domain-containing protein-OG0000067--------
GBC12030.1g23441.t1RIR_0098300Peptide-methionine (R)-S-oxide reductase-OG0002283YCL033C44.641.00E-46Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespanAN193267.942.00E-62Putative methionine sulfoxide reductase with a predicted role in the reduction of methionine sulfoxide to methionine
GBC12031.1g23442.t1RIR_0098400gata factor srep-OG0000059YER040W37.933.00E-13Transcriptional activator of genes regulated by nitrogen catabolite repression; localization and activity regulated by quality of nitrogen source and Ure2pAN017644.449.00E-16"Predicted GATA transcription factor involved in iron uptake, acts as a repressor of siderophore biosynthesis under high-iron conditions; mutants accumulate increased amounts of iron"
GBC12032.1g23443.t1RIR_0098500zinc finger family protein-OG0000059--------
GBC12033.1g23444.t1RIR_0098600"ATP-binding cassette, subfamily D (ALD),"-OG0000504YPL147W31.469.00E-97"Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa2p"AN101439.342.00E-157Peroxisomal long-chain acyl-CoA transporter; locus contains the conserved upstream open reading frame (uORF) AN1014-uORF
GBC12034.1g23445.t1RIR_0098700"guanyl-nucleotide exchange factor, hops complex"-OG0000683YDL077C24.383.00E-24"Subunit of the HOPS endocytic tethering complex; vacuole membrane protein that functions as a Rab GTPase effector, interacting with both GTP- and GDP-bound conformations of Ypt7p, facilitating tethering and promoting several membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking"AN1084934.566.00E-166Protein with similarity to Saccharomyces cerevisiae Vam6p/Vps39p; plays a role in vacuolar morphogenesis
GBC12035.1g23445.t2RIR_0098700"guanyl-nucleotide exchange factor, hops complex"-OG0000683----AN1084933.694.00E-56Protein with similarity to Saccharomyces cerevisiae Vam6p/Vps39p; plays a role in vacuolar morphogenesis
GBC12036.1g23446.t1RIR_0098800zinc finger bed domain-containing protein-OG0000008--------
GBC12037.1g23447.t1RIR_0098900hypothetical protein----------
GBC12038.1g23448.t1RIR_0099000serine/threonine protein kinase-OG0000000----AN582230.223.00E-11Serine/threonine protein kinase involved in DNA damage checkpoint and G2/M transition; ortholog of S. pombe wee1; inviable; arrests in cell cycle
GBC12039.1g23449.t1RIR_0099100serine/threonine protein kinase-OG0000000YNL298W28.83.00E-16"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN427931.825.00E-17Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea
GBC12040.1g23450.t1RIR_0099200cora family metal ion transporter-OG0004919----AN004238.714.00E-46"Has domain(s) with predicted metal ion transmembrane transporter activity, role in metal ion transport, transmembrane transport and membrane localization"
GBC12041.1g23451.t1RIR_0099300hypothetical protein----------
GBC12042.1g23452.t1RIR_0099400transmembrane protein 41a-a-like-OG0001101--------
GBC12043.1g23453.t1RIR_0099500actin cortical patch component lsb4-OG0000644YHR016C66.672.00E-61"Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication"AN416841.583.00E-91"Ortholog of A. fumigatus Af293 : Afu6g07880, A. niger CBS 513.88 : An11g02770, A. oryzae RIB40 : AO090003000147, Aspergillus wentii : Aspwe1_0121458 and Aspergillus sydowii : Aspsy1_1067771"
GBC12044.1g23454.t1RIR_0099600Cytochrome c peroxidaseAA2OG0001463YKR066C49.191.00E-70"Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress"AN1022064.688.00E-123Putatice cytochrome c peroxidase; intracellular; protein abundance decreased by menadione stress
GBC12045.1Tis13_347859RIR_0099610Tis13_347859----------
GBC12046.1g23455.t2RIR_0099700c2h2-type zinc finger transcription factor-OG0000117--------
GBC12047.1g23455.t1RIR_0099700c2h2-type zinc finger transcription factor-OG0000117--------
GBC12048.1g23456.t1RIR_0099800hypothetical protein-OG0001450--------
GBC12049.1g23457.t1RIR_0099900Acetoacetyl-CoA synthetase-OG0001949YAL054C24.323.00E-16"Acetyl-coA synthetase isoform; along with Acs2p, acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation; expressed during growth on nonfermentable carbon sources and under aerobic conditions"AN110347.143.00E-95"Has domain(s) with predicted acetoacetate-CoA ligase activity, catalytic activity and role in lipid metabolic process, metabolic process"
GBC12050.1g23458.t1RIR_0100000Acetoacetyl-CoA synthetase-OG0001949YLR153C29.133.00E-17"Acetyl-coA synthetase isoform; along with Acs1p, acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions"AN110339.312.00E-51"Has domain(s) with predicted acetoacetate-CoA ligase activity, catalytic activity and role in lipid metabolic process, metabolic process"
GBC12051.1g23459.t1RIR_0100100U3 small nucleolar RNA-associated protein 20-OG0002060YBL004W31.480Component of the small-subunit (SSU) processome; SSU processome is involved in the biogenesis of the 18S rRNAAN393828.330"Ortholog of A. fumigatus Af293 : Afu6g08240, A. niger CBS 513.88 : An11g01850, A. oryzae RIB40 : AO090003000101, Aspergillus wentii : Aspwe1_0177059 and Aspergillus sydowii : Aspsy1_0088917"
GBC12052.1g23460.t1RIR_0100200ubox domain containing protein-OG0005764--------
GBC12053.1g23461.t1RIR_0100300CDP-diacylglycerol-serine-OG0003357YER026C47.833.00E-64"Phosphatidylserine synthase; functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline"AN1070146.618.00E-67Ortholog(s) have CDP-diacylglycerol-serine O-phosphatidyltransferase activity
GBC12054.1g23461.t2RIR_0100300CDP-diacylglycerol-serine-OG0003357YER026C43.21.00E-50"Phosphatidylserine synthase; functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline"AN1070148.955.00E-52Ortholog(s) have CDP-diacylglycerol-serine O-phosphatidyltransferase activity
GBC12055.1g23462.t3RIR_0100400velvet factor-OG0000236----AN036352.382.00E-19"Component of the velvet complex composed of VelB, VeA, and LaeA that coordinates development and secondary metabolism in response to light"
GBC12056.1g23462.t2RIR_0100400velvet factor-OG0000236----AN036352.381.00E-19"Component of the velvet complex composed of VelB, VeA, and LaeA that coordinates development and secondary metabolism in response to light"
GBC12057.1g23462.t1RIR_0100400velvet factor-OG0000236----AN036351.815.00E-19"Component of the velvet complex composed of VelB, VeA, and LaeA that coordinates development and secondary metabolism in response to light"
GBC12058.1g23463.t1RIR_0100500Mitotic spindle assembly checkpoint protein-OG0003163YGL086W32.811.00E-16Coiled-coil protein involved in spindle-assembly checkpoint; required for inhibition of karyopherin/importin Pse1p (aka Kap121p) upon spindle assembly checkpoint arrest; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of anaphase promoting complex activity; forms a complex with Mad2p; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instabilityAN069627.831.00E-52Putative spindle assembly checkpoint protein that localizes to the nuclear pore complex
GBC12059.1g23464.t1RIR_0100600t5orf172 family protein-OG0004678----AN773238.663.00E-14"Ortholog of A. fumigatus Af293 : Afu5g08070, A. niger CBS 513.88 : An03g04260, A. oryzae RIB40 : AO090701000723, Aspergillus wentii : Aspwe1_0272371 and Aspergillus sydowii : Aspsy1_0153174"
GBC12060.1g23465.t1RIR_0100700Transcription factor CP2 and related proteins-OG0000922----AN487834.238.00E-30Putative transcription factor of unknown function; expression upregulated after exposure to farnesol
GBC12061.1g23466.t1RIR_0100800hypothetical protein-OG0008287--------
GBC12062.1g23467.t1RIR_0100900hypothetical protein----------
GBC12063.1g23468.t2RIR_0101000nefa-interacting nuclear protein nip30-OG0004374----AN127534.452.00E-11"Ortholog of A. fumigatus Af293 : Afu1g09920, A. niger CBS 513.88 : An08g01730, A. oryzae RIB40 : AO090038000461, Aspergillus wentii : Aspwe1_0343642 and Aspergillus sydowii : Aspsy1_0228584"
GBC12064.1g23468.t1RIR_0101000nefa-interacting nuclear protein nip30-OG0004374--------
GBC12065.1g23469.t1RIR_0101100mitochondrial conserved eukaryotic protein-OG0000979YAL046C54.791.00E-24Protein involved in mitochondrial function or organization; null mutant displays elevated frequency of mitochondrial genome loss----
GBC12066.1g23470.t1RIR_0101200ER to Golgi transport-related protein-OG0000666YML067C31.64.00E-32Protein localized to COPII-coated vesicles; forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) proteinAN767935.175.00E-48"Ortholog(s) have role in ER to Golgi vesicle-mediated transport and COPII-coated ER to Golgi transport vesicle, integral component of Golgi membrane, integral component of endoplasmic reticulum membrane localization"
GBC12067.1g23470.t2RIR_0101200ER to Golgi transport-related protein-OG0000666YML067C31.851.00E-32Protein localized to COPII-coated vesicles; forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) proteinAN767935.591.00E-48"Ortholog(s) have role in ER to Golgi vesicle-mediated transport and COPII-coated ER to Golgi transport vesicle, integral component of Golgi membrane, integral component of endoplasmic reticulum membrane localization"
GBC12068.1g23471.t1RIR_0101300Syntaxin 1B/2/3-OG0000303YMR183C34.013.00E-42"Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p; SSO2 has a paralog, SSO1, that arose from the whole genome duplication"AN341626.712.00E-17Similar to syntaxin proteins; SsoA-GFP localizes to the plasma membrane and to the hyphal tip
GBC12069.1g23472.t1RIR_0101400hypothetical protein----------
GBC12070.1g23473.t1RIR_0101500Glutaredoxin 3-OG0000436YDR513W44.792.00E-21"Cytoplasmic glutaredoxin; thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress; GRX2 has two in-frame start codons resulting in a shorter isoform that is retained in the cytosol and a longer form translocated to the mitochondrial matrix; GRX2 has a paralog, GRX1, that arose from the whole genome duplication"AN421544.715.00E-21"Ortholog(s) have glutathione disulfide oxidoreductase activity, glutathione peroxidase activity, glutathione transferase activity and role in glutathione metabolic process, pathogenesis, removal of superoxide radicals"
GBC12071.1g23474.t1RIR_0101600nst UDP-galactose transporter-OG0002241----AN420946.373.00E-111"Has domain(s) with predicted carbohydrate:proton symporter activity, pyrimidine nucleotide-sugar transmembrane transporter activity and role in carbohydrate transport, pyrimidine nucleotide-sugar transmembrane transport"
GBC12072.1g23475.t1RIR_0101700putative pyruvate transmembrane transporter-OG0001466YGR243W54.951.00E-30"Highly conserved subunit of mitochondrial pyruvate carrier; more highly expressed in glucose-containing minimal medium than in lactate-containing medium; expression regulated by osmotic and alkaline stresses; protein abundance increases in response to DNA replication stress; MPC3 has a paralog, MPC2, that arose from the whole genome duplication"AN876253.772.00E-32"Ortholog(s) have pyruvate transmembrane transporter activity, role in mitochondrial pyruvate transmembrane transport and mitochondrial membrane, plasma membrane localization"
GBC12073.1g23476.t1RIR_0101800hypothetical protein-OG0005336--------
GBC12074.1g23477.t1RIR_0101900Translation initiation factor eIF1-OG0001308YNL244C64.492.00E-42Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phaseAN474263.392.00E-37"Ortholog(s) have ribosomal small subunit binding, translation initiation factor activity, translation initiation factor binding activity and role in formation of translation preinitiation complex, maintenance of translational fidelity"
GBC12075.1g23478.t1RIR_0102000Solute carrier family 36-OG0000228YKL146W43.251.00E-141Vacuolar transporter; exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transportersAN447746.416.00E-165"Ortholog(s) have L-arginine transmembrane transporter activity, L-histidine transmembrane transporter activity, L-lysine transmembrane transporter activity"
GBC12076.1g23479.t2RIR_0102100hypothetical protein-OG0002172--------
GBC12077.1g23479.t1RIR_0102100hypothetical protein-OG0002172--------
GBC12078.1g23480.t1RIR_0102200zinc finger bed domain-containing protein-OG0000008--------
GBC12079.1g23481.t1RIR_0102300hypothetical protein----------
GBC12080.1g23482.t1RIR_0102400zinc finger bed domain-containing protein----------
GBC12081.1g23483.t1RIR_0102500"Phosphatidylinositol phospholipase C, delta"-OG0000496YPL268W32.371.00E-100"Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation"AN066435.372.00E-155"Putative 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase with a predicted role in phospholipid metabolism; directly linked to high-molecular-weight carbon source sensing"
GBC12082.1g23484.t1RIR_0102600iron-sulfur cluster assembly scaffold protein-OG0001787YPL135W79.533.00E-71"Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable; ISU1 has a paralog, ISU2, that arose from the whole genome duplication"AN465570.733.00E-61"Ortholog(s) have 2 iron, 2 sulfur cluster binding, ferrous iron binding, iron-sulfur transferase activity and role in [2Fe-2S] cluster assembly, cellular iron ion homeostasis, tRNA wobble uridine modification"
GBC12083.1g23485.t1RIR_0102700"Superoxide dismutase, Fe-Mn family"-OG0000525YJR101W26.21.00E-13Mitochondrial ribosomal protein of the small subunitAN514829.862.00E-25"Ortholog(s) have structural constituent of ribosome activity, role in cellular response to drug and mitochondrial small ribosomal subunit localization"
GBC12084.1g23486.t1RIR_0102800U6 snRNA-associated Sm-like protein LSm7-OG0000568YNL147W40.216.00E-16"Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress"AN076757.611.00E-28"Ortholog(s) have RNA binding, poly(U) RNA binding activity and role in mRNA splicing, via spliceosome, maturation of SSU-rRNA, nuclear-transcribed mRNA catabolic process"
GBC12086.1g23488.t1RIR_0103000myb-like transcription factor-OG0000136----AN837729.812.00E-11"Has domain(s) with predicted DNA binding, chromatin binding activity"
GBC12087.1g23489.t2RIR_0103100myb-related protein b-like-OG0005186--------
GBC12088.1g23489.t1RIR_0103100myb-related protein b-like-OG0005186--------
GBC12089.1g23490.t1RIR_0103200myb transcription factor-OG0000136--------
GBC12090.1g23491.t1RIR_0103300hypothetical protein----------
GBC12091.1g23492.t1RIR_0103400hypothetical protein----------
GBC12092.1g23493.t1RIR_0103500"trichome differentiation protein gl1, putative"----------
GBC12093.1Tis13_89495RIR_0103510Tis13_89495----------
GBC12094.1g23494.t1RIR_0103600hypothetical protein----------
GBC12095.1g23495.t1RIR_0103700myb-like transcription factor-OG0000136----AN027933.332.00E-12Putative transcription factor involved in regulation of asexual and sexual development and in response to nitrogen starvation; contains a myb-like DNA-binding domain
GBC12096.1g23496.t1RIR_0103800myb-like DNA-binding domain containing protein----------
GBC12097.1g23497.t1RIR_0103900myb-like transcription factor-OG0000136--------
GBC12099.1g23498.t1RIR_0104000helicase----------
GBC12103.1g23502.t1RIR_0104400"f-box/lrr-repeat protein 7-like, partial"-OG0000047----AN1051624.556.00E-11Putative F-box protein with a role in meiosis; NeddH-associated protein; required for ascospore development; transcript is highly expressed during sexual development
GBC12105.1g23504.t1RIR_0104600hypothetical protein----------
GBC12106.1g23505.t2RIR_0104700uvr/rep helicase----------
GBC12107.1g23505.t1RIR_0104700uvr/rep helicase----------
GBC12108.1g23505.t3RIR_0104700uvr/rep helicase----------
GBC12109.1g23506.t1RIR_0104800hypothetical protein----------
GBC12110.1g23507.t2RIR_0104900hypothetical protein----------
GBC12111.1g23507.t1RIR_0104900hypothetical protein----------
GBC12112.1Tis13_26942RIR_0104910Tis13_26942----------
GBC12114.1g23509.t1RIR_0105100hypothetical protein----------
GBC12116.1g23511.t1RIR_0105300hypothetical protein----------
GBC12117.1g23512.t1RIR_0105400hypothetical protein-OG0000004--------
GBC12123.1g23518.t1RIR_0106000DNA polymerase delta subunit 1-OG0000463----AN732524.591.00E-15"Ortholog(s) have DNA-directed DNA polymerase activity and role in DNA synthesis involved in UV-damage excision repair, mitotic DNA replication lagging strand elongation"
GBC12124.1g23519.t1RIR_0106100zinc finger bed domain-containing protein-OG0000008--------
GBC12126.1Tis13_88204RIR_0106120Tis13_88204----------
GBC12129.1g23521.t1RIR_0106300protein far1-related sequence 11-like isoform----------
GBC12134.1g23526.t1RIR_0106800transposase domain-containing protein-OG0000002--------
GBC12140.1g23531.t1RIR_0107300myb-like transcription factor-OG0000136----AN837727.351.00E-11"Has domain(s) with predicted DNA binding, chromatin binding activity"