home > Gene Annotation List

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NCBI IDProteinIDLocusTagProductIDCazyIDOrthGroupIDSGD IDidentevalAnnotationASpGD IDidentEvalAnnotation
GBC16861.1g29338.t1RIR_0489900hypothetical protein-OG0000010--------
GBC16862.1g29339.t1RIR_0490000Copper chaperone-OG0002457YLR216C48.114.00E-98Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; plays a role in determining prion variants; binds to Hsp82p and contributes to chaperone activity; protein abundance increases in response to DNA replication stressAN458355.462.00E-124Putative peptidyl-prolyl cis-trans isomerase D (PPIase); cyclophilin family member; protein abundance decreased by menadione stress; transcript levels increase during the unfolded-protein response (UPR) and in response to camptothecin
GBC16863.1g29340.t3RIR_0490100saga complex subunit spt8-OG0003873----AN207825.598.00E-23"Has domain(s) with predicted RNA polymerase II transcription cofactor activity, role in regulation of transcription by RNA polymerase II and mediator complex localization"
GBC16864.1g29340.t1RIR_0490100saga complex subunit spt8-OG0003873YEL052W39.582.00E-42Protein that may act as a chaperone for cytochrome c oxidase subunits; conserved protein; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domainAN702935.767.00E-52"Ortholog(s) have role in cellular response to oxidative stress, protein import into peroxisome matrix, protein quality control for misfolded or incompletely synthesized proteins and mitochondrial inner membrane localization"
GBC16865.1g29340.t2RIR_0490100saga complex subunit spt8-OG0003873YPL028W36.633.00E-78"Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis"AN140937.698.00E-74Putative acetyl-CoA C-acetyltransferase with a predicted role in fatty acid metabolism; intracellular; protein abundance decreased by menadione stress
GBC16866.1g29341.t1RIR_0490200Mitochondrial inner membrane protein COX18-OG0000807--------
GBC16867.1g29342.t1RIR_0490300Peptidyl-prolyl isomerase D-OG0000119--------
GBC16868.1g29343.t1RIR_0490400Peroxisome-assembly ATPase-OG0003152--------
GBC16869.1g29344.t1RIR_0490500Acetyl-Coenzyme A acyltransferase 2-OG0004495--------
GBC16870.1g29345.t1RIR_0490600putative mediator of RNA polymerase II-OG0002675--------
GBC16872.1g29347.t1RIR_0490800RNA-directed DNA polymerase from mobile element-OG0000001YDR377W34.381.00E-14"Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis"AN1156539.783.00E-18"Ortholog(s) have proton-transporting ATP synthase activity, rotational mechanism activity and role in ATP synthesis coupled proton transport"
GBC16874.1g29348.t1RIR_0490900microtubule-associated protein 1b-OG0000030----AN367840.854.00E-13"Ortholog of A. fumigatus Af293 : Afu4g12490, A. niger CBS 513.88 : An01g07920, A. oryzae RIB40 : AO090009000462, Aspergillus wentii : Aspwe1_0033898 and Aspergillus sydowii : Aspsy1_0046608"
GBC16875.1g29348.t2RIR_0490900microtubule-associated protein 1b-OG0000030--------
GBC16876.1g29349.t1RIR_0491000Autophagy-related protein 9-OG0003077--------
GBC16877.1g29350.t1RIR_0491100F-type H+-transporting ATPase subunit f-OG0003044--------
GBC16878.1g29351.t1RIR_0491200"Isovaleryl-CoA dehydrogenase 2, mitochondrial"-OG0003555--------
GBC16879.1g29352.t1RIR_0491300guanyl-nucleotide exchange factor-OG0000415--------
GBC16880.1Tis13_7915RIR_0491310Tis13_7915-OG0004906----AN117232.311.00E-97Has domain(s) with predicted nucleic acid binding activity and role in mRNA processing
GBC16885.1g29356.t1RIR_0491700G patch domain-containing protein 1-OG0003438YGR278W31.311.00E-69Spliceosome-associated protein that is required for pre-mRNA splicing; necessary for Prp2p function at the first catalytic step of splicing; has similarity to S. pombe Cwf22p; CWC22 is an essential proteinAN028963.860Ortholog(s) have U2-type spliceosomal complex localization
GBC16886.1g29357.t2RIR_0491800"Nucleolar protein, component of the small"-OG0002357YLL029W41.261.00E-137"Protein involved in negative regulation of iron regulon transcription; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation"AN1100556.80Has domain(s) with predicted hydrolase activity and role in cellular process
GBC16887.1g29357.t1RIR_0491800"Nucleolar protein, component of the small"-OG0002357YML092C65.182.00E-108Alpha 2 subunit of the 20S proteasomeAN672660.875.00E-113"Ortholog(s) have role in proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process"
GBC16888.1g29358.t1RIR_0491900hypothetical protein----------
GBC16889.1g29359.t1RIR_0492000transmembrane protein 199-OG0004494--------
GBC16890.1g29360.t1RIR_0492100Pre-mRNA-splicing factor CWC22-OG0001075--------
GBC16891.1g29361.t1RIR_0492200Xaa-Pro aminopeptidase-OG0001041--------
GBC16892.1g29362.t1RIR_049230020S proteasome subunit alpha 2-OG0000088----AN787030.663.00E-11"Ortholog of A. fumigatus Af293 : Afu3g01650, Afu6g11970, Neosartorya fischeri NRRL 181 : NFIA_002730, NFIA_057640 and Aspergillus versicolor : Aspve1_0204208"
GBC16893.1g29363.t1RIR_0492400"glucan endo-1,3-alpha-glucosidase agn1"-OG0000429YKR074W47.921.00E-21Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; YKR074W is not an essential gene; null mutant displays elevated frequency of mitochondrial genome loss----
GBC16894.1g29364.t1RIR_0492500"glucan endo-1,3-alpha-glucosidase agn1"-OG0000429----AN750142.212.00E-48"Ortholog of A. fumigatus Af293 : Afu2g05440, A. niger CBS 513.88 : An11g09330, A. oryzae RIB40 : AO090001000656, Aspergillus wentii : Aspwe1_0046263 and Aspergillus sydowii : Aspsy1_0045848"
GBC16895.1g29365.t1RIR_0492600meprin a subunit beta--YML008C50.818.00E-133"Delta(24)-sterol C-methyltransferase; converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to lipid particles, the plasma membrane-associated endoplasmic reticulum, and the mitochondrial outer membrane"AN714653.429.00E-144Putative S-adenosyl-methionine delta-24-sterol-C-methyltransferase with a predicted role in sterol metabolism
GBC16896.1g29366.t1RIR_0492700"glucan endo-1,3-alpha-glucosidase agn1"-OG0000429YPR020W34.621.00E-14"Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex, which in turn determines oligomerization of the complex and the shape of inner membrane cristae"AN094333.645.00E-11Putative mitochondrial F1F0-ATP synthase subunit g; ortholog of S. cerevisiae Atp20p; expression reduced after exposure to farnesol
GBC16897.1g29367.t1RIR_0492800"glucan endo-1,3-alpha-glucosidase agn1"-OG0000429YIR037W60.132.00E-65"Thiol peroxidase; functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor; HYR1 has a paralog, GPX1, that arose from the whole genome duplication"AN284644.884.00E-52Putative glutathione peroxidase with a predicted role in glutathione biosynthesis; protein induced by farnesol
GBC16898.1g29368.t1RIR_0492900cytoplasm protein-OG0004353--------
GBC16899.1g29369.t1RIR_0493000glucose-induced degradation complex subunit-OG0001105--------
GBC16900.1g29370.t1RIR_0493100Sterol 24-C-methyltransferase-OG0001744----AN884128.373.00E-30Has domain(s) with predicted nucleus localization
GBC16901.1g29371.t1RIR_0493200F-type H+-transporting ATPase subunit g-OG0001453YFL034W29.66.00E-43Putative integral membrane protein that interacts with Rpp0p; Rpp0p is a component of the ribosomal stalkAN626835.56.00E-67Has domain(s) with predicted role in regulation of translational fidelity
GBC16902.1g29372.t1RIR_0493300Glutathione peroxidase-OG0000556YFL034W29.66.00E-43Putative integral membrane protein that interacts with Rpp0p; Rpp0p is a component of the ribosomal stalkAN626835.58.00E-67Has domain(s) with predicted role in regulation of translational fidelity
GBC16903.1g29373.t2RIR_0493400Target of EGR1 protein 1-OG0004754YDL006W48.57.00E-88"Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation"AN689246.555.00E-95Putative protein serine/threonine phosphatase; reduced growth on AVICEL medium and reduced eglA and eglB expression
GBC16904.1g29373.t1RIR_0493400Target of EGR1 protein 1-OG0004754YDL006W47.742.00E-79"Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation"AN689245.651.00E-87Putative protein serine/threonine phosphatase; reduced growth on AVICEL medium and reduced eglA and eglB expression
GBC16905.1g29374.t1RIR_0493500putative Protein DGCR14-OG0003428YLR246W32.762.00E-41Subunit of a palmitoyltransferase; this complex adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole; palmitoyltransferase is composed of Erf2p and Shr5pAN476335.793.00E-59Has domain(s) with predicted zinc ion binding activity
GBC16906.1g29375.t1RIR_0493600integral membrane protein; yfl034wp-OG0001216YDR397C45.676.00E-27Subunit of a heterodimeric NC2 transcription regulator complex; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta; complex also includes Bur6pAN935857.641.00E-47"Ortholog(s) have sequence-specific DNA binding, transcription coactivator activity, transcription corepressor activity"
GBC16907.1g29375.t2RIR_0493600integral membrane protein; yfl034wp-OG0001216YER179W29.751.00E-28"Meiosis-specific recombinase required for repair of double-strand breaks; also required for pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p"AN123728.438.00E-27Protein with homology to Saccharomyces cerevisiae Rad51p and to bacterial RecA; involved in the DNA damage response; mutants are sensitive to DNA double-strand breaks and have defects in homologous recombination
GBC16908.1g29376.t2RIR_0493700Protein phosphatase PTC1-OG0003934YPL045W26.26.00E-61Subunit of the HOPS and the CORVET complexes; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stagesAN691145.540"Has domain(s) with predicted role in intracellular protein transport, vacuole organization and cytoplasm localization"
GBC16909.1g29376.t1RIR_0493700Protein phosphatase PTC1-OG0003934YER179W27.932.00E-26"Meiosis-specific recombinase required for repair of double-strand breaks; also required for pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p"AN123727.611.00E-23Protein with homology to Saccharomyces cerevisiae Rad51p and to bacterial RecA; involved in the DNA damage response; mutants are sensitive to DNA double-strand breaks and have defects in homologous recombination
GBC16910.1g29377.t1RIR_0493800Palmitoyltransferase ZDHHC9/14/18-OG0000112YKL010C23.992.00E-20"Ubiquitin-protein ligase (E3); interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins; relative distribution to the nucleus increases upon DNA replication stress"AN174621.542.00E-27Putative HECT ubiquitin ligase
GBC16911.1g29378.t1RIR_0493900class 2 transcription repressor nc2 beta-OG0002111--------
GBC16912.1g29379.t1RIR_0494000DNA repair protein rad51-OG0000210YNL302C60.874.00E-56"Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication"AN406064.033.00E-60Putative ribosomal protein S16
GBC16913.1g29379.t2RIR_0494000DNA repair protein rad51-OG0000210YNL302C60.875.00E-56"Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication"AN406064.033.00E-60Putative ribosomal protein S16
GBC16914.1g29380.t1RIR_0494100Vacuolar protein sorting-associated protein 16-OG0002959YIL075C44.650Subunit of the 26S proteasome; substrate of the N-acetyltransferase Nat1p; protein abundance increases in response to DNA replication stressAN170053.660Putative 26S proteasome regulatory subunit; transcript upregulated in response to camptothecin
GBC16915.1g29381.t1RIR_0494200ubiquitin-protein ligase ufd4-OG0002568--------
GBC16916.1g29381.t2RIR_0494200ubiquitin-protein ligase ufd4-OG0002568--------
GBC16917.1g29382.t2RIR_049430040S ribosomal protein S19-OG0001311--------
GBC16918.1g29382.t1RIR_049430040S ribosomal protein S19-OG0001311--------
GBC16919.1g29383.t1RIR_049440026S proteasome regulatory subunit N2-OG0002077--------
GBC16922.1g29386.t1RIR_0494700RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC16923.1g29387.t1RIR_0494800reverse transcriptase-OG0000001--------
GBC16929.1JEMT01018126.1_cds_EXX66977.1_13041RIR_0495310JEMT01018126.1_cds_EXX66977.1_13041----------
GBC16930.1g29393.t1RIR_0495400hypothetical protein-OG0000332----AN1217927.432.00E-13Protein of unknown function
GBC16931.1g29394.t1RIR_0495500Type I protein arginine methyltransferase-OG0004095YHL015W66.333.00E-41Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; homologous to mammalian ribosomal protein S20 and bacterial S10AN459469.755.00E-50"Ortholog(s) have role in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and cytosolic small ribosomal subunit, hyphal cell wall, yeast-form cell wall localization"
GBC16932.1g29395.t1RIR_0495600"T-complex protein 1, theta subunit-1"-OG0001729----AN1220835.832.00E-33"Ortholog of A. fumigatus Af293 : Afu7g03650, A. oryzae RIB40 : AO090673000003, Aspergillus wentii : Aspwe1_0026236, Aspergillus sydowii : Aspsy1_0165430 and Aspergillus terreus NIH2624 : ATET_02779"
GBC16933.1g29396.t1RIR_0495700leydig cell tumor 10 kda protein homolog-OG0003932YJL133W49.833.00E-99"Iron transporter, mediates Fe2+ transport across inner mito membrane; mitochondrial carrier family member; active under low-iron conditions; may transport other cations; MRS3 has a paralog, MRS4, that arose from the whole genome duplication"AN369059.937.00E-121"Ortholog(s) have iron ion transmembrane transporter activity, role in RNA splicing, iron import into the mitochondrion, iron ion homeostasis and mitochondrion, plasma membrane localization"
GBC16934.1g29396.t2RIR_0495700leydig cell tumor 10 kda protein homolog-OG0003932YNL113W62.032.00E-31RNA polymerase subunit AC19; common to RNA polymerases I and IIIAN655855.423.00E-31"Ortholog(s) have RNA polymerase I activity, RNA polymerase III activity and role in tRNA transcription by RNA polymerase III, transcription by RNA polymerase I"
GBC16935.1g29397.t1RIR_0495800f-box protein pof12-OG0003213YLR272C39.190"Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin, tRNA gene clustering at the nucleolus, and silencing at the mating type locus; required for replication slow zone (RSZ) breakage following Mec1p inactivation"AN345147.190"Ortholog(s) have ATPase activity, double-stranded DNA binding, single-stranded DNA binding activity and role in mitotic chromosome condensation"
GBC16936.1g29398.t1RIR_049590040S ribosomal protein S20-OG0001438--------
GBC16937.1g29399.t1RIR_0496000tpr repeat protein oca3/ ER membrane protein-OG0002589--------
GBC16938.1g29400.t1RIR_0496100Solute carrier family 25 (mitochondrial iron-OG0001140YBR241C32.182.00E-78"Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene; YBR241C has a paralog, VPS73, that arose from the whole genome duplication"AN1236632.162.00E-44Ortholog(s) have fungal-type vacuole membrane localization
GBC16939.1g29401.t1RIR_0496200DNA-directed RNA polymerases I and III subunit-OG0000680--------
GBC16940.1g29402.t1RIR_0496300Condensin complex subunit 1-OG0001598--------
GBC16941.1g29403.t1RIR_0496400glucose dehydrogenase-OG0000001--------
GBC16943.1g29405.t1RIR_0496600glucose transporter type 3-OG0000019--------
GBC16944.1g29406.t1RIR_0496700cell death-inducing p53-target protein 1-like-OG0000530--------
GBC16945.1g29407.t1RIR_0496800hypothetical protein----------
GBC16946.1g29408.t1RIR_0496900lipopolysaccharide-induced tumor necrosis-OG0000530YML010W23.972.00E-24"Component of the universally conserved Spt4/5 complex (DSIF complex); the complex has multiple roles in concert with RNA polymerases I and II, including regulation of transcription elongation, RNA processing, quality control, and transcription-coupled DNA repair"AN169824.453.00E-36"Ortholog(s) have role in negative regulation of antisense RNA transcription, positive regulation of transcription elongation from RNA polymerase II promoter and DSIF complex localization"
GBC16947.1g29409.t1RIR_0497000lipopolysaccharide-induced tumor necrosis-OG0000530--------
GBC16948.1g29410.t1RIR_0497100hypothetical protein----------
GBC16949.1g29411.t1RIR_0497200Lipopolysaccharide-induced tumor necrosis-OG0000530--------
GBC16950.1g29412.t1RIR_0497300Alpha-tubulin N-acetyltransferase 1-OG0004752--------
GBC16951.1g29413.t1RIR_0497400Transcription elongation factor SPT5-OG0001590--------
GBC16952.1g29414.t1RIR_0497500hypothetical protein----------
GBC16953.1g29415.t1RIR_0497600hypothetical protein--YDR523C28.663.00E-21Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by themAN597329.591.00E-19Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC16955.1g29417.t1RIR_0497800hypothetical protein----------
GBC16956.1Tis13_21010RIR_0497810Tis13_21010----------
GBC16957.1g29418.t1RIR_0497900hypothetical protein----------
GBC16958.1g29419.t1RIR_0498000serine/threonine protein kinase-OG0000000--------
GBC16959.1g29420.t1RIR_0498100hypothetical protein----------
GBC16963.1g29423.t1RIR_0498400hypothetical protein----------
GBC16964.1g29424.t2RIR_0498500hypothetical protein----------
GBC16965.1g29424.t1RIR_0498500hypothetical protein----------
GBC16966.1g29425.t1RIR_0498600hypothetical protein----------
GBC16967.1g29426.t1RIR_0498700transcriptional regulator----------
GBC16969.1g29427.t1RIR_0498800hypothetical protein----------
GBC16970.1JEMT01026599.1_cds_EXX58817.1_21209RIR_0498810JEMT01026599.1_cds_EXX58817.1_21209----------
GBC16971.1JEMT01026599.1_cds_EXX58818.1_21210RIR_0498820JEMT01026599.1_cds_EXX58818.1_21210----------
GBC16972.1g29428.t1RIR_0498900hypothetical protein----------
GBC16974.1Tis13_23822RIR_0499010Tis13_23822----------
GBC16977.1g29431.t1RIR_0499200hypothetical protein----------
GBC16978.1g29432.t1RIR_0499300hypothetical protein----------
GBC16979.1Tis13_342378RIR_0499310Tis13_342378----------
GBC16980.1Tis13_342377RIR_0499320Tis13_342377----------
GBC16981.1g29433.t1RIR_0499400hypothetical protein----------
GBC16982.1g29434.t1RIR_0499500probable RNA-directed DNA polymerase from-OG0000001--------
GBC16985.1g29436.t1RIR_0499700hypothetical protein----------
GBC16988.1g29439.t1RIR_0500000hypothetical protein--YLR409C36.030Subunit of U3-containing 90S preribosome and SSU processome complexes; involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma; Small Subunit processome is also known as SSU processomeAN829334.458.00E-164Has domain(s) with predicted role in rRNA processing and small-subunit processome localization
GBC16990.1g29440.t2RIR_0500100hypothetical protein----------
GBC16991.1g29440.t1RIR_0500100hypothetical protein----------
GBC16992.1g29441.t1RIR_0500200hypothetical protein----------
GBC16993.1g29442.t1RIR_0500300U3 small nucleolar RNA-associated protein 21-OG0001448--------
GBC16994.1g29443.t1RIR_0500400Charged multivesicular body protein 4-OG0001952--------
GBC16995.1g29444.t1RIR_0500500putative UDP-galactose transporter-OG0003741--------
GBC16996.1g29445.t1RIR_0500600-DH dehydrogenase (ubiquinone) 1 alpha-OG0000816----AN803240.22.00E-71Putative C-3 sterol dehydrogenase; expression upregulated after exposure to farnesol
GBC16997.1g29446.t1RIR_0500700hypothetical protein----------
GBC16998.1Tis13_29355RIR_0500710Tis13_29355----------
GBC16999.1g29447.t1RIR_0500800ribosomal protein subunit l51-b-OG0002582--------
GBC17000.1g29448.t1RIR_0500900hypothetical protein----------
GBC17001.1g29449.t1RIR_0501000S-adenosylmethionine synthetase-OG0004195--------
GBC17002.1g29450.t1RIR_0501100hypothetical protein----------
GBC17005.1g29452.t1RIR_0501300nudt9 protein-OG0000036--------
GBC17006.1Tis13_35043RIR_0501310Tis13_35043------AN133036.493.00E-48Predicted glycosylphosphatidylinositol (GPI)-anchored protein
GBC17007.1g29453.t1RIR_0501400hypothetical protein--YAL034W-A31.13.00E-18Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND)AN096028.674.00E-23"Ortholog(s) have role in mitotic spindle organization, protein localization to kinetochore, spindle localization and kinetochore localization"
GBC17008.1g29454.t1RIR_0501500hypothetical protein--YER015W32.298.00E-91"Medium chain fatty acyl-CoA synthetase; activates imported fatty acids; accepts a wide range of fatty acid chain lengths with a preference for medium chains, C9:0-C13:0; localized to the peroxisome; comparative analysis suggests that a mitochondrially targeted form may result from translation starting at a non-canonical codon upstream of the annotated start codon"AN828036.671.00E-124Putative long-chain-fatty-acid-CoA ligase with a predicted role in fatty acid metabolism; transcript induced in the presence of short and long chain fatty acids
GBC17009.1g29455.t1RIR_0501600hypothetical protein--YER070W67.190"Major isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; relative distribution to the nucleus increases upon DNA replication stress; RNR1 has a paralog, RNR3, that arose from the whole genome duplication"AN438068.320Putative ribonucleotide reductase large chain with a predicted role in nucleotide salvage pathways; transcript upregulated in response to camptothecin
GBC17010.1g29456.t1RIR_0501700hypothetical protein--YPR047W48.586.00E-138"Mitochondrial phenylalanyl-tRNA synthetase; active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase"AN625345.76.00E-142Putative phenylalanine tRNA synthetase alpha subunit
GBC17011.1g29457.t1RIR_0501800phospholipase c-OG0001925--------
GBC17012.1g29458.t1RIR_0501900Kinetochore protein Mis12/MTW1-OG0003828YGR147C28.032.00E-11Protein of unknown function; has an apparent role in acetylation of N-terminal methionine residuesAN430929.412.00E-14"Ortholog(s) have role in N-terminal peptidyl-methionine acetylation, cellular response to drug"
GBC17013.1g29459.t1RIR_0502000Long-chain-fatty-acid-CoA synthetase-OG0000168--------
GBC17014.1g29460.t1RIR_0502100Ribonucleoside-diphosphate reductase subunit M1-OG0000987--------
GBC17015.1g29461.t1RIR_0502200Phenylalanyl-tRNA synthetase alpha chain-OG0002756--------
GBC17016.1g29462.t1RIR_0502300mRNA processing protein-OG0002036--------
GBC17017.1g29463.t1RIR_0502400peptide alpha-n-acetyltransferase nat2-OG0001360--------
GBC17021.1JEMT01023953.1_cds_EXX63416.1_16611RIR_0502710JEMT01023953.1_cds_EXX63416.1_16611----------
GBC17022.1g29467.t1RIR_0502800hypothetical protein-OG0001812--------
GBC17023.1g29468.t2RIR_0502900hypothetical protein-OG0000117--------
GBC17024.1g29468.t1RIR_0502900hypothetical protein-OG0000117--------
GBC17025.1g29469.t1RIR_0503000hypothetical protein-OG0000002--------
GBC17026.1g29469.t2RIR_0503000hypothetical protein-OG0000002--------
GBC17027.1g29470.t1RIR_0503100RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC17031.1JEMT01026816.1_cds_EXX58450.1_21580RIR_0503410JEMT01026816.1_cds_EXX58450.1_21580----------
GBC17034.1g29476.t1RIR_0503700hypothetical protein----------
GBC17035.1g29477.t1RIR_0503800hypothetical protein-OG0004869--------
GBC17036.1g29477.t2RIR_0503800hypothetical protein-OG0004869--------
GBC17037.1g29477.t3RIR_0503800hypothetical protein-OG0004869--------
GBC17043.1g29482.t1RIR_0504300RNA-directed DNA polymerase from mobile element-OG0000001YIR035C38.221.00E-48Putative cytoplasmic short-chain dehydrogenase/reductaseAN935740.845.00E-62Has domain(s) with predicted oxidoreductase activity and role in metabolic process
GBC17047.1g29486.t1RIR_0504700hypothetical protein----------
GBC17048.1g29487.t1RIR_0504800hypothetical protein-OG0007010--------
GBC17049.1g29488.t1RIR_0504900sepiapterin reductase family protein irc24-OG0004059--------
GBC17050.1g29489.t1RIR_0505000retrovirus-related protein-OG0000001--------
GBC17054.1g29493.t1RIR_0505400RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC17062.1g29501.t1RIR_0506200hypothetical protein-OG0000026--------
GBC17065.1g29504.t1RIR_0506500reverse transcriptase-OG0000001--------
GBC17067.1g29506.t1RIR_0506700ribonuclease h----------
GBC17069.1g29508.t1RIR_0506900hypothetical protein----------
GBC17070.1g29509.t1RIR_0507000hypothetical protein----------
GBC17071.1g29510.t1RIR_0507100zinc finger bed domain-containing protein-OG0000077--------
GBC17073.1g29512.t1RIR_0507300hypothetical protein-OG0000002--------
GBC17074.1g29513.t1RIR_0507400zinc finger bed domain-containing protein----------
GBC17075.1g29514.t1RIR_0507500transposase domain-containing protein-OG0000002--------
GBC17079.1g29518.t1RIR_0507900hypothetical protein----------
GBC17080.1g29519.t1RIR_0508000duf659 and ribonuclease h-like domain containing----------
GBC17082.1g29521.t1RIR_0508200hypothetical protein----------
GBC17083.1g29522.t1RIR_0508300reverse transcriptase-like protein-OG0000001--------
GBC17084.1g29523.t1RIR_0508400CENP-b protein 1-OG0000010--------
GBC17090.1g29529.t1RIR_0509000RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC17091.1g29530.t1RIR_0509100zinc finger bed domain-containing protein-OG0002715--------
GBC17096.1g29535.t1RIR_0509600ribonuclease h--YMR171C42.292.00E-56Specificity factor required for Rsp5p-dependent ubiquitination; also required for sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2pAN083158.136.00E-126"Ortholog of A. fumigatus Af293 : Afu1g14910, A. niger CBS 513.88 : An01g13030, A. oryzae RIB40 : AO090005001241, Aspergillus wentii : Aspwe1_0171775 and Aspergillus sydowii : Aspsy1_0139300"
GBC17097.1g29536.t1RIR_0509700reverse transcriptase-OG0000001--------
GBC17102.1g29541.t1RIR_0510200endosome protein-OG0000658--------
GBC17103.1g29542.t1RIR_0510300rad51-associated protein brh2-OG0003519--------
GBC17104.1g29542.t2RIR_0510300rad51-associated protein brh2-OG0003519--------
GBC17109.1JEMT01019309.1_cds_EXX66236.1_13792RIR_0510710JEMT01019309.1_cds_EXX66236.1_13792-OG0004893--------
GBC17115.1g29551.t1RIR_0511200outer membrane protein iml2-OG0000417--------
GBC17119.1g29555.t1RIR_0511600transposase domain-containing protein-OG0000002--------
GBC17122.1g29558.t1RIR_0511900"zinc finger protein 862-like, partial"--YDR081C24.44.00E-13Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditionsAN615637.87.00E-35"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC17124.1Tis13_6459RIR_0511920Tis13_6459----------
GBC17127.1g29561.t1RIR_0512200hypothetical protein-OG0000080--------
GBC17128.1g29562.t1RIR_0512300CENP-b protein 1-OG0000010--------
GBC17129.1JEMT01023537.1_cds_EXX64303.1_15729RIR_0512310JEMT01023537.1_cds_EXX64303.1_15729----------
GBC17131.1JEMT01015055.1_cds_EXX72782.1_7251RIR_0512410JEMT01015055.1_cds_EXX72782.1_7251-OG0000047--------
GBC17135.1g29567.t1RIR_0512800hypothetical protein------AN362330.943.00E-23Subunit 7 of the COP9 signalosome; required for formation of cleistothecia; putative pre-induction sporulation protein
GBC17138.1g29570.t1RIR_0513100Actin-related protein 8-OG0003526--------
GBC17139.1g29571.t3RIR_0513200cop9 signalosome complex subunit 7-OG0002642YLR285W49.351.00E-68S-adenosylmethionine-dependent methyltransferase; has a role in rDNA silencing and in lifespan determinationAN250038.31.00E-49Putative nicotinamide N-methyltransferase
GBC17140.1g29571.t1_oku1RIR_0513200cop9 signalosome complex subunit 7-OG0002642--------
GBC17141.1g29571.t2_oku1RIR_0513200cop9 signalosome complex subunit 7-OG0002642--------
GBC17142.1g29571.t1_oku2RIR_0513210WD40 domain-containing protein-OG0000510--------
GBC17145.1g29573.t1RIR_0513400Nicotinamide N-methyltransferase-OG0001648--------
GBC17146.1g29574.t1RIR_0513500hypothetical protein----------
GBC17147.1JEMT01025203.1_cds_EXX61626.1_18407RIR_0513510JEMT01025203.1_cds_EXX61626.1_18407----------
GBC17150.1g29577.t1RIR_0513800dead-like helicase----------
GBC17156.1JEMT01027112.1_cds_EXX57982.1_22047RIR_0514310JEMT01027112.1_cds_EXX57982.1_22047----------
GBC17157.1g29583.t1RIR_0514400hypothetical protein----------
GBC17158.1g29584.t1RIR_0514500hypothetical protein----------
GBC17159.1Tis13_283150RIR_0514510Tis13_283150----------
GBC17160.1g29585.t1RIR_0514600hypothetical protein-OG0003748--------
GBC17161.1g29586.t1RIR_0514700hypothetical protein-OG0003747--------
GBC17162.1g29587.t1RIR_0514800hypothetical protein----------
GBC17164.1g29589.t1RIR_0515000hypothetical protein----------
GBC17165.1g29590.t1RIR_0515100hypothetical protein----------
GBC17170.1g29595.t2RIR_0515600hypothetical protein----------
GBC17171.1g29595.t1RIR_0515600hypothetical protein----------
GBC17172.1g29596.t1RIR_0515700hypothetical protein----------
GBC17173.1g29597.t1RIR_0515800hypothetical protein-OG0000010--------
GBC17176.1g29598.t1RIR_0515900hypothetical protein----------
GBC17177.1g29599.t1RIR_0516000triose phosphate transporter-OG0002188--------
GBC17178.1g29600.t1RIR_0516100hypothetical protein-OG0000008--------
GBC17179.1g29600.t2RIR_0516100hypothetical protein-OG0000008--------
GBC17180.1g29601.t1RIR_0516200zinc finger bed domain-containing protein----------
GBC17181.1JEMT01026917.1_cds_EXX58340.1_21687RIR_0516210JEMT01026917.1_cds_EXX58340.1_21687----------
GBC17182.1g29602.t1RIR_0516300hypothetical protein-OG0000026--------
GBC17183.1g29603.t1RIR_0516400hypothetical protein-OG0000026----AN036825.993.00E-12"Has domain(s) with predicted RNA binding, RNA-DNA hybrid ribonuclease activity, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in RNA-dependent DNA biosynthetic process"
GBC17188.1g29608.t1RIR_0516900transposase domain-containing protein-OG0000002--------
GBC17189.1g29609.t1RIR_0517000RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC17190.1g29610.t1RIR_0517100hypothetical protein-OG0000001--------
GBC17191.1g29611.t1RIR_0517200Translation initiation factor 4B-OG0002012--------
GBC17192.1g29612.t1RIR_0517300zinc finger bed domain-containing protein-OG0000008--------
GBC17194.1g29613.t1RIR_0517400duf659 and ribonuclease h-like domain containing-OG0002452--------
GBC17198.1g29617.t1RIR_0517800reverse transcriptase-OG0000001--------
GBC17201.1g29620.t1RIR_0518100hypothetical protein----------
GBC17204.1g29623.t1RIR_0518400RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC17208.1g29627.t1RIR_0518800putative protein-primed b-family DNA polymerase----------
GBC17211.1g29629.t1RIR_0519000transposase-OG0000105--------
GBC17214.1g29632.t1RIR_0519300hypothetical protein----------
GBC17218.1g29636.t1RIR_0519700Glutathione-disulfide reductase-OG0000999--------
GBC17219.1g29637.t2RIR_0519800Zn(II)2cys6 transcription factor-OG0000147--------
GBC17220.1g29637.t1RIR_0519800Zn(II)2cys6 transcription factor-OG0000147--------
GBC17221.1g29638.t1RIR_0519900hypothetical protein----------
GBC17222.1g29639.t1RIR_0520000hypothetical protein----------
GBC17223.1g29640.t1RIR_0520100hypothetical protein----------
GBC17224.1g29641.t1RIR_0520200hypothetical protein----------
GBC17225.1g29642.t1RIR_0520300hypothetical protein----------
GBC17226.1g29643.t1RIR_0520400zinc finger bed domain-containing protein----------
GBC17229.1g29645.t1RIR_0520600RNA-directed DNA polymerase from mobile element-OG0000001YOR113W38.983.00E-20"Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia"AN6503403.00E-25"Has domain(s) with predicted nucleic acid binding, zinc ion binding activity"
GBC17233.1g29648.t1RIR_0520900CENP-b protein 1-OG0000010--------
GBC17235.1g29650.t1RIR_0521100zinc finger protein 239-like-OG0000003YOR204W33.082.00E-55"ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase; required for translation initiation of all yeast mRNAs; binds to mRNA cap-associated factors, and binding stimulates Ded1p RNA-dependent ATPase activity; mutation in human homolog DBY is associated with male infertility; human homolog DDX3X complements ded1 null mutation; DED1 has a paralog, DBP1, that arose from the whole genome duplication"AN1055734.272.00E-55Putative ATP-dependent RNA helicase; protein levels decrease in response to farnesol
GBC17236.1JEMT01024387.1_cds_EXX62852.1_17177RIR_0521110JEMT01024387.1_cds_EXX62852.1_17177--YHR102W23.358.00E-13"Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"AN438525.492.00E-12"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC17238.1g29651.t1RIR_0521200hypothetical protein-OG0001017--------
GBC17239.1g29652.t1RIR_0521300"DNA-binding protein eta2, putative"-OG0000136--------
GBC17240.1g29653.t1RIR_0521400nitrilase-like protein-OG0004431--------
GBC17241.1g29654.t1RIR_0521500ATP-dependent RNA helicase DDX21-OG0004439--------
GBC17242.1g29655.t1RIR_0521600serine/threonine protein kinase-OG0000000--------
GBC17243.1g29656.t2RIR_0521700hypothetical protein--YBL061C32.034.00E-27"Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication"AN081024.912.00E-24Protein with a predicted role in ER-associated protein degradation
GBC17244.1g29656.t1RIR_0521700hypothetical protein----------
GBC17245.1g29657.t1RIR_0521800glutamate-rich protein 3----------
GBC17246.1g29658.t1RIR_0521900hypothetical protein----------
GBC17247.1g29659.t1RIR_0522000ATPase aaa-OG0005760YNL298W30.494.00E-13"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"----
GBC17249.1g29661.t1RIR_0522200sel1 repeat domain-containing protein-OG0000000--------
GBC17251.1Tis13_75777RIR_0522220Tis13_75777----------
GBC17252.1g29662.t1RIR_0522300hypothetical protein--YPL140C24.158.00E-12"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"----
GBC17253.1g29663.t1RIR_0522400serine-threonine protein kinase----------
GBC17254.1g29664.t1RIR_0522500dual serine/threonine and tyrosine protein----------
GBC17255.1Tis13_30368RIR_0522510Tis13_30368----------
GBC17256.1g29665.t1RIR_0522600SEL1 protein-OG0000000YPL203W29.091.00E-15cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxiaAN156030.382.00E-13"Polo-like kinase, involved in initiation of mitosis and mitotic progression; transcript upregulated in response to camptothecin; reported as essential in one study, viable with strong growth defect in another study; mutant sensitive to NaCl"
GBC17258.1g29666.t1RIR_0522700protein kinase--YMR001C31.379.00E-13Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN156030.383.00E-12"Polo-like kinase, involved in initiation of mitosis and mitotic progression; transcript upregulated in response to camptothecin; reported as essential in one study, viable with strong growth defect in another study; mutant sensitive to NaCl"
GBC17259.1g29667.t1RIR_0522800hypothetical protein----------
GBC17260.1JEMT01026168.1_cds_EXX59832.1_20196RIR_0522810JEMT01026168.1_cds_EXX59832.1_20196----------
GBC17262.1g29668.t1RIR_0522900protein kinase-OG0000248--------
GBC17263.1g29669.t1RIR_0523000protein kinase--YPL030W31.822.00E-52tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential geneAN872127.596.00E-37Has domain(s) with predicted methyltransferase activity
GBC17264.1g29670.t1RIR_0523100protein kinase-OG0000248--------
GBC17266.1JEMT01027196.1_cds_EXX57921.1_22105RIR_0523120JEMT01027196.1_cds_EXX57921.1_22105--YBL061C32.848.00E-24"Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication"AN081027.697.00E-29Protein with a predicted role in ER-associated protein degradation
GBC17267.1g29671.t1RIR_0523200hypothetical protein----------
GBC17268.1g29672.t1RIR_0523300hypothetical protein--YDR477W27.693.00E-17"AMP-activated serine/threonine protein kinase; found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth in response to starvation; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ubiquitin ligase"AN581529.391.00E-20Aurora protein serine/threonine kinase
GBC17269.1g29673.t1RIR_0523400tRNA (uracil-O(2)-)-methyltransferase-OG0003362YGL083W29.122.00E-76Putative kinase; suppressor of GTPase mutant; similar to bovine rhodopsin kinase; may have a role in intracellular sterol transportAN432238.761.00E-130Ortholog(s) have role in negative regulation of TORC1 signaling and cytoplasm localization
GBC17270.1g29674.t1RIR_0523500hypothetical protein----------
GBC17271.1g29675.t1RIR_0523600hypothetical protein----------
GBC17272.1g29676.t1RIR_0523700SEL1 protein-OG0000000--------
GBC17273.1Tis13_4779RIR_0523710Tis13_4779----------
GBC17274.1g29677.t1RIR_0523800SEL1 protein-OG0000000--------
GBC17275.1g29678.t1RIR_0523900SCY1-like protein 2-OG0002477--------
GBC17276.1g29679.t1RIR_0524000Targeting protein for Xklp2-OG0002154--------
GBC17279.1g29681.t1RIR_0524200gastrula zinc finger protein xlcgf46.1-OG0000287YPR107C36.521.00E-28Essential RNA-binding component of cleavage and polyadenylation factor; contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation; relocalizes to the cytosol in response to hypoxiaAN029834.294.00E-27"Ortholog(s) have RNA binding activity, role in mRNA polyadenylation, pre-mRNA cleavage required for polyadenylation, response to drug and cytosol, mRNA cleavage and polyadenylation specificity factor complex localization"
GBC17280.1g29682.t1RIR_0524300hypothetical protein-OG0000366YDL064W55.567.00E-63SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC)AN439966.671.00E-76SumO conjugation (E2) enzyme
GBC17283.1g29685.t1RIR_0524600putative Smplekin-OG0002401--------
GBC17284.1g29686.t1RIR_0524700serine-threonine protein phosphatase-OG0003782YOL016C25.155.00E-13"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication"AN597328.773.00E-11Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC17285.1JEMT01017405.1_cds_EXX68120.1_11913RIR_0524710JEMT01017405.1_cds_EXX68120.1_11913-OG0001505----AN1032931.349.00E-45Predicted mariner transposon-related ORF
GBC17286.1g29687.t1RIR_0524800Ubiquitin conjugating enzyme E2 I-OG0001894--------
GBC17287.1g29688.t1RIR_0524900Tyrosyl-DNA phosphodiesterase 1-OG0001410--------
GBC17288.1g29689.t1RIR_0525000"11beta-hydroxysteroid dehydrogenase-like,"-OG0001972YOL113W37.621.00E-12"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN156027.887.00E-11"Polo-like kinase, involved in initiation of mitosis and mitotic progression; transcript upregulated in response to camptothecin; reported as essential in one study, viable with strong growth defect in another study; mutant sensitive to NaCl"
GBC17289.1g29690.t1RIR_0525100protein n-terminal glutamine-OG0004202--------
GBC17290.1g29691.t1RIR_0525200kinase family protein--YMR001C26.534.00E-14Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN773727.756.00E-12Ortholog(s) have protein serine/threonine kinase activity
GBC17291.1g29692.t1RIR_0525300transposable element tc3 transposase-OG0000005--------
GBC17292.1Tis13_342507RIR_0525310Tis13_342507--YOL113W34.964.00E-14"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN773730.439.00E-14Ortholog(s) have protein serine/threonine kinase activity
GBC17293.1g29693.t1RIR_0525400hypothetical protein--YPL209C27.752.00E-15"Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest"AN950431.858.00E-13Cell-cycle regulated serine/threonine protein kinase; essential for entry into mitosis; temperature sensitive mutants arrest in G2-phase of the cell cycle; high levels of NimA are lethal
GBC17294.1g29694.t1RIR_0525500dual serine/threonine and tyrosine protein----------
GBC17295.1g29695.t1RIR_0525600hypothetical protein----------
GBC17296.1g29696.t1RIR_0525700protein kinase----------
GBC17298.1g29697.t1RIR_0525800protein kinase--YPL209C29.862.00E-13"Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest"----
GBC17299.1g29698.t1RIR_0525900serine-threonine protein kinase-OG0000000--------
GBC17300.1Tis13_344761RIR_0525910Tis13_344761----------
GBC17301.1g29699.t1RIR_0526000hypothetical protein--YFR014C26.347.00E-13"Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication"----
GBC17302.1g29700.t1RIR_0526100esv-1-7----------
GBC17303.1Tis13_319958RIR_0526110Tis13_319958----------
GBC17304.1g29701.t1RIR_0526200protein kinase----------
GBC17307.1g29704.t1RIR_0526500protein kinase--YNL298W35.592.00E-14"Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication"AN206732.621.00E-12Predicted PAK (p21-activated kinase) family protein; similar to Saccharomyces cerevisiae Ste20p; mutants have increased pigment production
GBC17308.1JEMT01018198.1_cds_EXX66896.1_13134RIR_0526510JEMT01018198.1_cds_EXX66896.1_13134----------
GBC17310.1g29706.t1RIR_0526700serine-threonine protein kinase-OG0000248--------
GBC17312.1g29708.t1RIR_0526900protein far1-related sequence 11-like isoform-OG0000030--------
GBC17313.1g29709.t1RIR_0527000"protein kinase, putative"-OG0000000YKL166C28.317.00E-15"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN597329.91.00E-12Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC17314.1JEMT01018589.1_cds_EXX66609.1_13419RIR_0527010JEMT01018589.1_cds_EXX66609.1_13419--YOL016C26.513.00E-12"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication"AN567428.487.00E-11"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC17317.1Tis13_346807RIR_0527040Tis13_346807----------
GBC17318.1g29710.t1RIR_0527100"crinkler family protein, putative"----------
GBC17319.1g29711.t1RIR_0527200protein kinase--YMR001C26.647.00E-13Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrateAN418933.013.00E-11"Essential mitogen-activated protein kinase kinase (MAPKK); mutants arrest as branched germlings, but the phenotype is remediated by NaCl or sucrose"
GBC17320.1g29712.t1RIR_0527300protein kinase----------
GBC17321.1g29713.t1RIR_0527400serine/threonine kinase motif-containing----------