GBC41234.1 | g18252.t1 | RIR_2466900 | eukaryotic translation initiation factor 2c 2 | - | OG0000170 | - | - | - | - | AN4385 | 24.23 | 2.00E-15 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC41235.1 | g18252.t2 | RIR_2466900 | eukaryotic translation initiation factor 2c 2 | - | OG0000170 | YAR019C | 27.32 | 6.00E-15 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN5674 | 27.68 | 1.00E-14 | "MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development" |
GBC41236.1 | g18253.t1 | RIR_2467000 | protein of unknown function | - | - | YBR082C | 67.36 | 2.00E-63 | "Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication" | AN2761 | 69.39 | 3.00E-66 | Putative ubiquitin-conjugating enzyme E2; transcript upregulated in response to camptothecin |
GBC41237.1 | g18254.t1 | RIR_2467100 | tyrosine kinase domain protein | - | OG0000041 | YKL126W | 28 | 5.00E-11 | "Serine/threonine protein kinase; phosphorylates and downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p (inhibitors of serine:palmitoyl-coenzyme A transferase) by phosphorylation in response to compromised sphingolipid synthesis; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK; YPK1 has a paralog, YPK2, that arose from the whole genome duplication" | - | - | - | - |
GBC41240.1 | g18256.t1 | RIR_2467300 | btb/poz domain-containing protein 6-a-like | - | OG0000006 | YDR059C | 67.83 | 6.00E-72 | "Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication" | AN2761 | 74.66 | 1.00E-75 | Putative ubiquitin-conjugating enzyme E2; transcript upregulated in response to camptothecin |
GBC41242.1 | g18257.t1 | RIR_2467400 | protein far1-related sequence 11-like | - | OG0000030 | - | - | - | - | - | - | - | - |
GBC41243.1 | g18258.t1 | RIR_2467500 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41247.1 | g18260.t1 | RIR_2467700 | kelch-like protein 17 | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC41248.1 | g18261.t1 | RIR_2467800 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41250.1 | g18262.t1 | RIR_2467900 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41251.1 | g18263.t1 | RIR_2468000 | serine/threonine protein kinase | - | OG0000090 | - | - | - | - | - | - | - | - |
GBC41252.1 | g18264.t1 | RIR_2468100 | cytochrome p450 monooxygenase | - | OG0000114 | YMR104C | 33.04 | 5.00E-22 | "Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication" | AN5973 | 29.39 | 1.00E-19 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC41254.1 | g18265.t2 | RIR_2468200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41255.1 | g18265.t1 | RIR_2468200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41256.1 | Tis13_26775 | RIR_2468210 | Tis13_26775 | - | - | YML061C | 26.95 | 4.00E-24 | "DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells" | AN6895 | 27.89 | 1.00E-25 | "Has domain(s) with predicted DNA helicase activity and role in DNA repair, telomere maintenance" |
GBC41257.1 | g18266.t1 | RIR_2468300 | DNA topoisomerase II | - | OG0001606 | YJL095W | 24.14 | 2.00E-15 | MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase | AN4279 | 30.87 | 4.00E-14 | Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea |
GBC41258.1 | g18267.t1 | RIR_2468400 | hypothetical protein | - | - | YBR082C | 64.18 | 6.00E-59 | "Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication" | AN2761 | 66.42 | 9.00E-59 | Putative ubiquitin-conjugating enzyme E2; transcript upregulated in response to camptothecin |
GBC41259.1 | Tis13_102626 | RIR_2468480 | Tis13_102626 | - | - | YMR104C | 32.3 | 4.00E-20 | "Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication" | AN5973 | 30.32 | 3.00E-17 | Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies |
GBC41260.1 | g18268.t1 | RIR_2468500 | hypothetical protein | - | - | YBR082C | 54.73 | 9.00E-46 | "Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication" | AN2761 | 56 | 1.00E-45 | Putative ubiquitin-conjugating enzyme E2; transcript upregulated in response to camptothecin |
GBC41260.1 | g18268.t1 | RIR_2468500 | hypothetical protein | - | - | YNL298W | 26.67 | 1.00E-11 | "Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication" | AN4385 | 24.24 | 5.00E-15 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC41260.1 | g18268.t1 | RIR_2468500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41260.1 | g18268.t1 | RIR_2468500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41261.1 | Tis13_9810 | RIR_2468510 | Tis13_9810 | - | - | YJL164C | 34.17 | 3.00E-21 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication" | AN5815 | 26.15 | 2.00E-19 | Aurora protein serine/threonine kinase |
GBC41261.1 | Tis13_9810 | RIR_2468510 | Tis13_9810 | - | - | - | - | - | - | - | - | - | - |
GBC41262.1 | g18269.t1 | RIR_2468600 | ATP-dependent DNA helicase pif1-like | - | OG0000037 | YBL061C | 29.37 | 3.00E-21 | "Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication" | AN0810 | 24.24 | 1.00E-27 | Protein with a predicted role in ER-associated protein degradation |
GBC41263.1 | g18270.t1 | RIR_2468700 | serine/threonine-protein kinase ht1 | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41264.1 | g18271.t1 | RIR_2468800 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41265.1 | g18272.t1 | RIR_2468900 | serine/threonine-protein kinase sty8-like | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41268.1 | g18274.t1 | RIR_2469100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41272.1 | g18276.t1 | RIR_2469300 | tripartite motif-containing protein 29 isoform | - | - | - | - | - | - | - | - | - | - |
GBC41273.1 | g18277.t1 | RIR_2469400 | hsp70 family ATPase ssa3 | - | - | - | - | - | - | - | - | - | - |
GBC41274.1 | g18278.t1 | RIR_2469500 | SEL1 protein | - | OG0000000 | YPL140C | 26.34 | 4.00E-13 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication" | - | - | - | - |
GBC41275.1 | g18279.t1 | RIR_2469600 | serine/threonine protein kinase | - | OG0000038 | - | - | - | - | - | - | - | - |
GBC41277.1 | g18280.t1 | RIR_2469700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41278.1 | g18281.t1 | RIR_2469800 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41279.1 | g18282.t1 | RIR_2469900 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41280.1 | g18283.t1 | RIR_2470000 | serine/threonine-protein kinase ht1-like | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41282.1 | Tis13_31998 | RIR_2470020 | Tis13_31998 | - | OG0000000 | YDR059C | 51.76 | 2.00E-18 | "Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication" | AN2761 | 55.29 | 3.00E-19 | Putative ubiquitin-conjugating enzyme E2; transcript upregulated in response to camptothecin |
GBC41283.1 | g18284.t1 | RIR_2470100 | transposable element tc3 transposase | - | OG0000005 | - | - | - | - | - | - | - | - |
GBC41284.1 | g18285.t1 | RIR_2470200 | hypothetical protein | - | - | YOL113W | 25.86 | 1.00E-13 | "Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication" | AN4385 | 31.08 | 1.00E-13 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC41285.1 | g18286.t1 | RIR_2470300 | mitogen-activated protein kinase kinase kinase | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41286.1 | g18287.t1 | RIR_2470400 | tyrosine kinase domain protein | - | OG0000041 | YDR059C | 60.4 | 2.00E-64 | "Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication" | AN2761 | 65.1 | 3.00E-66 | Putative ubiquitin-conjugating enzyme E2; transcript upregulated in response to camptothecin |
GBC41287.1 | g18288.t1 | RIR_2470500 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | YPL153C | 30.43 | 4.00E-17 | DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxia | AN2269 | 32.42 | 4.00E-19 | "Mitogen-activated protein kinase kinase (MAPKK), component of a signaling module SteD-SteC-MkkB-MpkB that controls coordination of development and secondary metabolism; mutant has a moderate growth defect and arrested sexual development" |
GBC41288.1 | g18289.t1 | RIR_2470600 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41289.1 | g18290.t1 | RIR_2470700 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41291.1 | g18291.t1 | RIR_2470800 | zinc finger bed domain-containing protein | - | OG0000008 | - | - | - | - | - | - | - | - |
GBC41292.1 | g18292.t1 | RIR_2470900 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41294.1 | g18294.t1 | RIR_2471100 | sel1 repeat domain-containing protein | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41295.1 | g18295.t1 | RIR_2471200 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41297.1 | g18297.t1 | RIR_2471400 | zinc finger mym-type protein 4-like | - | - | - | - | - | - | - | - | - | - |
GBC41298.1 | Tis13_94931 | RIR_2471410 | Tis13_94931 | - | - | - | - | - | - | - | - | - | - |
GBC41299.1 | g18298.t1 | RIR_2471500 | serine/threonine protein kinase | - | OG0000000 | YJL164C | 30.08 | 6.00E-23 | "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication" | AN5815 | 33.33 | 5.00E-22 | Aurora protein serine/threonine kinase |
GBC41300.1 | Tis13_65827 | RIR_2471510 | Tis13_65827 | - | OG0000008 | YKL126W | 28.99 | 2.00E-14 | "Serine/threonine protein kinase; phosphorylates and downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p (inhibitors of serine:palmitoyl-coenzyme A transferase) by phosphorylation in response to compromised sphingolipid synthesis; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK; YPK1 has a paralog, YPK2, that arose from the whole genome duplication" | AN4385 | 33.33 | 8.00E-14 | "Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl" |
GBC41301.1 | g18299.t1 | RIR_2471600 | zinc finger bed domain-containing protein | - | OG0000008 | - | - | - | - | - | - | - | - |
GBC41302.1 | JEMT01028768.1_cds_EXX53768.1_26256 | RIR_2471610 | JEMT01028768.1_cds_EXX53768.1_26256 | - | OG0000003 | - | - | - | - | - | - | - | - |
GBC41303.1 | JEMT01028768.1_cds_EXX53769.1_26257 | RIR_2471620 | JEMT01028768.1_cds_EXX53769.1_26257 | - | - | - | - | - | - | - | - | - | - |
GBC41304.1 | g18300.t1 | RIR_2471700 | "p-type ATPase, calcium transporting" | - | OG0000307 | - | - | - | - | - | - | - | - |
GBC41305.1 | g18301.t1 | RIR_2471800 | hypothetical protein | - | OG0004555 | - | - | - | - | - | - | - | - |
GBC41306.1 | g18302.t1 | RIR_2471900 | hypothetical protein | - | OG0004555 | YAR019C | 30.47 | 2.00E-23 | Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress | AN2269 | 31.73 | 2.00E-22 | "Mitogen-activated protein kinase kinase (MAPKK), component of a signaling module SteD-SteC-MkkB-MpkB that controls coordination of development and secondary metabolism; mutant has a moderate growth defect and arrested sexual development" |
GBC41307.1 | JEMT01028768.1_cds_EXX53773.1_26261 | RIR_2471910 | JEMT01028768.1_cds_EXX53773.1_26261 | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41308.1 | g18303.t1 | RIR_2472000 | tkl protein kinase | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41309.1 | g18304.t1 | RIR_2472100 | hypothetical protein | - | OG0001797 | - | - | - | - | - | - | - | - |
GBC41311.1 | g18305.t1 | RIR_2472200 | protein kinase | - | OG0000041 | YPL153C | 29.48 | 2.00E-18 | DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxia | AN2269 | 32.88 | 2.00E-17 | "Mitogen-activated protein kinase kinase (MAPKK), component of a signaling module SteD-SteC-MkkB-MpkB that controls coordination of development and secondary metabolism; mutant has a moderate growth defect and arrested sexual development" |
GBC41312.1 | g18306.t1 | RIR_2472300 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41313.1 | g18307.t1 | RIR_2472400 | serine/threonine-protein kinase ht1 | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41314.1 | Tis13_8488 | RIR_2472410 | Tis13_8488 | - | - | - | - | - | - | - | - | - | - |
GBC41315.1 | g18308.t1 | RIR_2472500 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41316.1 | g18309.t1 | RIR_2472600 | spore wall assembly -related protein | - | OG0002250 | - | - | - | - | - | - | - | - |
GBC41318.1 | g18310.t1 | RIR_2472700 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41320.1 | g18312.t1 | RIR_2472900 | serine/threonine protein kinase | - | OG0000174 | - | - | - | - | - | - | - | - |
GBC41321.1 | g18313.t1 | RIR_2473000 | retrotransposable element | - | OG0000004 | - | - | - | - | - | - | - | - |
GBC41322.1 | g18314.t1 | RIR_2473100 | ubiquitin-conjugating enzyme e2 | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41323.1 | g18315.t1 | RIR_2473200 | zinc finger bed domain-containing protein | - | OG0000008 | - | - | - | - | - | - | - | - |
GBC41324.1 | Tis13_58870 | RIR_2473210 | Tis13_58870 | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41325.1 | g18316.t1 | RIR_2473300 | ubiquitin-conjugating enzyme e2 | - | OG0000103 | YLR096W | 32.07 | 3.00E-21 | "Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication" | AN5815 | 29.92 | 4.00E-24 | Aurora protein serine/threonine kinase |
GBC41327.1 | Tis13_926 | RIR_2473320 | Tis13_926 | - | - | - | - | - | - | - | - | - | - |
GBC41328.1 | g18317.t1 | RIR_2473400 | ubiquitin-conjugating enzyme e2 | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41330.1 | g18318.t1 | RIR_2473500 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41331.1 | g18319.t1 | RIR_2473600 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | AN1777 | 23.46 | 7.00E-25 | "Has domain(s) with predicted zinc ion binding activity, role in transcription, DNA-templated and nucleus localization" |
GBC41332.1 | g18320.t1 | RIR_2473700 | calmodulin-dependent protein kinase | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41333.1 | g18321.t1 | RIR_2473800 | rab9 effector protein with kelch motifs-like | - | OG0000021 | - | - | - | - | - | - | - | - |
GBC41334.1 | g18322.t1 | RIR_2473900 | ribonuclease hi | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC41336.1 | g18324.t1 | RIR_2474100 | serine/threonine protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC41338.1 | g18326.t1 | RIR_2474300 | serine/threonine-protein kinase sty8-like | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41339.1 | g18327.t1 | RIR_2474400 | mitogen-activated protein kinase kinase kinase | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41340.1 | g18328.t1 | RIR_2474500 | ubiquitin-conjugating enzyme e2 | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41341.1 | g18329.t1 | RIR_2474600 | wd40 repeat-like protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41343.1 | g18331.t1 | RIR_2474800 | similar to raf/atn-like protein kinase | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41344.1 | g18332.t1 | RIR_2474900 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41345.1 | g18333.t1 | RIR_2475000 | hypothetical protein | - | OG0000432 | - | - | - | - | - | - | - | - |
GBC41346.1 | g18334.t1 | RIR_2475100 | serine-enriched protein | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC41348.1 | g18335.t1 | RIR_2475200 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41349.1 | g18336.t1 | RIR_2475300 | mitogen-activated protein kinase kinase kinase | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41350.1 | g18337.t1 | RIR_2475400 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41352.1 | g18338.t1 | RIR_2475500 | duf659 and ribonuclease h-like domain containing | - | - | - | - | - | - | - | - | - | - |
GBC41356.1 | g18341.t1 | RIR_2475800 | serine/threonine protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC41358.1 | g18343.t1 | RIR_2476000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41360.1 | g18345.t1 | RIR_2476200 | ATP-dependent DNA helicase PIF1 | - | OG0000037 | - | - | - | - | - | - | - | - |
GBC41361.1 | g18346.t1 | RIR_2476300 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41362.1 | Tis13_75932 | RIR_2476310 | Tis13_75932 | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41363.1 | g18347.t1 | RIR_2476400 | serine/threonine protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC41364.1 | g18348.t1 | RIR_2476500 | ubiquitin-conjugating enzyme e2 | - | OG0000008 | - | - | - | - | - | - | - | - |
GBC41365.1 | g18349.t1 | RIR_2476600 | tyrosine kinase domain protein | - | OG0000041 | - | - | - | - | - | - | - | - |
GBC41366.1 | g18350.t1 | RIR_2476700 | kelch repeat protein | - | OG0000021 | - | - | - | - | AN10619 | 36.89 | 2.00E-13 | "Has domain(s) with predicted carboxy-lyase activity, catalytic activity, pyridoxal phosphate binding activity and role in carboxylic acid metabolic process" |
GBC41367.1 | g18351.t1 | RIR_2476800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41368.1 | g18352.t1 | RIR_2476900 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41369.1 | g18353.t1 | RIR_2477000 | kelch repeat protein | - | OG0000021 | - | - | - | - | - | - | - | - |
GBC41370.1 | g18354.t1 | RIR_2477100 | cobalamin biosynthesis protein cobt | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41371.1 | g18355.t1 | RIR_2477200 | hypothetical protein | - | OG0000022 | - | - | - | - | - | - | - | - |
GBC41374.1 | g18357.t1 | RIR_2477400 | mata_hmg | - | - | - | - | - | - | - | - | - | - |
GBC41377.1 | g18359.t1 | RIR_2477600 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41380.1 | g18361.t1 | RIR_2477800 | hypothetical protein | - | - | YBR160W | 58.7 | 2.00E-124 | "Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1 (CLNs), S and G2/M (CLBs) phase cyclins, which provide substrate specificity; regulates cell cycle and basal transcription, chromosome duplication and segregation, lipid biosynthesis, membrane trafficking, polarized growth, and morphogenesis; abundance increases in DNA replication stress; transcript induction in osmostress involves antisense RNA" | AN8261 | 63.99 | 7.00E-140 | Cyclin-dependent protein kinase; role in regulation of development in response to phosphate availability; interacts with cyclin Pho80; lethal in combination with mutations in phoB; mutant is sensitive to NaCl |
GBC41381.1 | Tis13_19016 | RIR_2477810 | Tis13_19016 | - | - | YDR337W | 42.24 | 2.00E-22 | Mitochondrial ribosomal protein of the small subunit | AN3173 | 27.48 | 3.00E-20 | "Ortholog(s) have structural constituent of ribosome activity and mitochondrial membrane, mitochondrial small ribosomal subunit localization" |
GBC41382.1 | g18362.t1 | RIR_2477900 | protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41383.1 | g18363.t1 | RIR_2478000 | protein kinase | - | - | YLR348C | 48.11 | 1.00E-89 | "Mitochondrial dicarboxylate carrier; integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix" | AN6254 | 50.71 | 1.00E-101 | Putative mitochondrial dicarboxylate:inorganic phosphate antiporter |
GBC41386.1 | g18365.t1 | RIR_2478200 | putative serine/threonine-protein | - | - | - | - | - | - | - | - | - | - |
GBC41387.1 | g18366.t1 | RIR_2478300 | polo kinase cdc5 | - | - | - | - | - | - | - | - | - | - |
GBC41388.1 | g18367.t1 | RIR_2478400 | hypothetical protein | - | OG0000060 | YOL129W | 36.26 | 3.00E-22 | Vacuolar membrane protein of unknown function; involved in vacuolar protein sorting; also detected in the mitochondria | AN6544 | 37.16 | 9.00E-21 | "Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway and Vps55/Vps68 complex, fungal-type vacuole membrane localization" |
GBC41389.1 | g18368.t1 | RIR_2478500 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41390.1 | Tis13_48178 | RIR_2478510 | Tis13_48178 | - | - | YPL209C | 52.31 | 7.00E-85 | "Aurora kinase of conserved chromosomal passenger complex; mediates release on mono-oriented kinetochores from microtubules in meiosis I, also release of kinetochores from cluster at SPBs at meiosis exit; helps maintain condensed chromosomes during anaphase, early telophase; required for SPB cohesion and prevention of multipolar spindle formation; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest" | AN5815 | 54.65 | 3.00E-99 | Aurora protein serine/threonine kinase |
GBC41391.1 | g18369.t1 | RIR_2478600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41392.1 | g18370.t1 | RIR_2478700 | serine-threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41393.1 | g18371.t1 | RIR_2478800 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41394.1 | g18372.t1 | RIR_2478900 | Ubiquitin-conjugating enzyme E2 D | - | OG0000103 | - | - | - | - | - | - | - | - |
GBC41395.1 | g18373.t1 | RIR_2479000 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41396.1 | g18374.t1 | RIR_2479100 | ribonuclease h | - | - | - | - | - | - | - | - | - | - |
GBC41398.1 | g18376.t1 | RIR_2479300 | gastrula zinc finger protein xlcgf46.1 | - | - | - | - | - | - | - | - | - | - |
GBC41400.1 | g18378.t1 | RIR_2479500 | hypothetical protein | - | OG0000004 | - | - | - | - | - | - | - | - |
GBC41404.1 | g18382.t1 | RIR_2479900 | reverse transcriptase | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC41407.1 | g18384.t1 | RIR_2480100 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41408.1 | g18385.t1 | RIR_2480200 | protein kinase | - | - | - | - | - | - | - | - | - | - |
GBC41409.1 | JEMT01025908.1_cds_EXX60497.1_19532 | RIR_2480210 | JEMT01025908.1_cds_EXX60497.1_19532 | - | OG0000027 | - | - | - | - | - | - | - | - |
GBC41410.1 | g18386.t3 | RIR_2480300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41411.1 | g18386.t2 | RIR_2480300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41412.1 | g18386.t1 | RIR_2480300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41413.1 | g18387.t1 | RIR_2480400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41414.1 | g18388.t1 | RIR_2480500 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41415.1 | JEMT01015225.1_cds_EXX72582.1_7445 | RIR_2480510 | JEMT01015225.1_cds_EXX72582.1_7445 | - | - | - | - | - | - | - | - | - | - |
GBC41416.1 | JEMT01015225.1_cds_EXX72583.1_7446 | RIR_2480520 | JEMT01015225.1_cds_EXX72583.1_7446 | - | - | - | - | - | - | - | - | - | - |
GBC41417.1 | g18389.t1 | RIR_2480600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41419.1 | g18390.t1 | RIR_2480700 | serine/threonine protein kinase | - | OG0000000 | YLL034C | 53.25 | 0 | "Putative ATPase of the AAA family; required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions" | AN1366 | 48.83 | 0 | "Has domain(s) with predicted ATP binding, nucleoside-triphosphatase activity, nucleotide binding activity" |
GBC41421.1 | g18392.t1 | RIR_2480900 | putative rve super family integrase | - | OG0000031 | YHR011W | 45.79 | 2.00E-104 | Probable mitochondrial seryl-tRNA synthetase; mutant displays increased invasive and pseudohyphal growth | AN10353 | 38.68 | 2.00E-97 | Protein with similarity to seryl tRNA synthase; required for conidial germination; expression reduced after exposure to farnesol |
GBC41422.1 | g18393.t1 | RIR_2481000 | hypothetical protein | - | - | - | - | - | - | AN10991 | 25.2 | 6.00E-18 | Ortholog(s) have 4-amino-4-deoxychorismate lyase activity and role in folic acid biosynthetic process |
GBC41423.1 | g18394.t1 | RIR_2481100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41426.1 | g18397.t1 | RIR_2481400 | ribonuclease h | - | OG0000001 | - | - | - | - | AN5874 | 29.38 | 8.00E-20 | Putative LaeA-like methyltransferase |
GBC41427.1 | g18398.t1 | RIR_2481500 | reverse transcriptase | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC41432.1 | g18403.t1 | RIR_2482000 | d5-like helicase-primase | - | OG0000364 | - | - | - | - | - | - | - | - |
GBC41433.1 | g18404.t1 | RIR_2482100 | serine/threonine protein kinase | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41434.1 | JEMT01010108.1_cds_EXX77778.1_2253 | RIR_2482110 | JEMT01010108.1_cds_EXX77778.1_2253 | - | - | - | - | - | - | - | - | - | - |
GBC41435.1 | Tis13_342698 | RIR_2482120 | Tis13_342698 | - | - | - | - | - | - | - | - | - | - |
GBC41436.1 | g18405.t1 | RIR_2482200 | "regulator of chromosome condensation rcc1," | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41437.1 | g18406.t1 | RIR_2482300 | serine/threonine protein kinase | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41438.1 | g18407.t1 | RIR_2482400 | "cgg triplet repeat-binding protein 1, partial" | - | - | - | - | - | - | - | - | - | - |
GBC41439.1 | g18408.t1 | RIR_2482500 | transcriptional activator | - | OG0000255 | - | - | - | - | - | - | - | - |
GBC41440.1 | g18409.t1 | RIR_2482600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41441.1 | g18410.t1 | RIR_2482700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41442.1 | g18411.t1 | RIR_2482800 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41443.1 | g18412.t1 | RIR_2482900 | "mata_hmg, partial" | - | - | - | - | - | - | - | - | - | - |
GBC41444.1 | g18413.t1 | RIR_2483000 | fasciclin-domain-containing protein | - | OG0000393 | - | - | - | - | - | - | - | - |
GBC41445.1 | g18414.t1 | RIR_2483100 | GTPase imap family member 6 | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41446.1 | g18415.t1 | RIR_2483200 | GTPase imap family member 6 | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41447.1 | g18416.t1 | RIR_2483300 | GTPase imap family member 6 | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41448.1 | g18417.t1 | RIR_2483400 | "regulator of chromosome condensation rcc1," | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41452.1 | g18420.t1 | RIR_2483700 | transposase domain-containing protein | - | OG0000002 | YDR172W | 55.58 | 0 | "Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)]" | AN2080 | 48.94 | 5.00E-176 | "Ortholog(s) have GTP binding, translation release factor activity, role in cytoplasmic translational termination and cytosolic ribosome, translation release factor complex localization" |
GBC41454.1 | JEMT01028094.1_cds_EXX55616.1_24415 | RIR_2483810 | JEMT01028094.1_cds_EXX55616.1_24415 | - | - | YGL205W | 28.91 | 2.00E-40 | Fatty-acyl coenzyme A oxidase; involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix | AN6752 | 29.89 | 5.00E-40 | Putative multifunctional enzyme with a predicted role in fatty acid degradation; required for beta-oxidation |
GBC41457.1 | g15471.t1 | RIR_2484100 | RNA-directed DNA polymerase from mobile element | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC41461.1 | g15475.t1 | RIR_2484500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41462.1 | g15476.t1 | RIR_2484600 | RNA-directed DNA polymerase from mobile element | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC41465.1 | g15479.t1 | RIR_2484900 | zinc finger bed domain-containing protein | - | OG0000008 | YDL064W | 63.25 | 2.00E-54 | SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) | AN4399 | 73.28 | 1.00E-61 | SumO conjugation (E2) enzyme |
GBC41467.1 | g15481.t1 | RIR_2485100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41468.1 | Tis13_337945 | RIR_2485110 | Tis13_337945 | - | - | - | - | - | - | AN7483 | 34.72 | 8.00E-35 | "Ortholog of A. nidulans FGSC A4 : AN4092, A. fumigatus Af293 : Afu2g05710, A. oryzae RIB40 : AO090001000688, Neosartorya fischeri NRRL 181 : NFIA_082430 and Aspergillus versicolor : Aspve1_0043503" |
GBC41469.1 | g15482.t1 | RIR_2485200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41470.1 | g15483.t1 | RIR_2485300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41471.1 | g15484.t1 | RIR_2485400 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41472.1 | g15485.t1 | RIR_2485500 | "riboflavin aldehydeforming enzyme, putative" | - | OG0000140 | - | - | - | - | - | - | - | - |
GBC41473.1 | g15486.t1 | RIR_2485600 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41474.1 | g15487.t1 | RIR_2485700 | pyridoxal-dependent decarboxylase domain | - | OG0001374 | - | - | - | - | - | - | - | - |
GBC41475.1 | g15488.t1 | RIR_2485800 | isoprenylcysteine carboxyl methyltransferase | - | OG0002181 | YJR142W | 33.33 | 4.00E-64 | 8-oxo-dGTP diphosphatase of the Nudix hydrolase family; converts diphosphates of damaged forms of thiamin to monophosphates; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition | AN0193 | 44.35 | 8.00E-65 | Ortholog(s) have 8-oxo-dGDP phosphatase activity |
GBC41476.1 | g15489.t1 | RIR_2485900 | pe_pgrs | - | - | YNL141W | 21.5 | 7.00E-11 | Adenine deaminase (adenine aminohydrolase); converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome | AN0662 | 39.35 | 1.00E-74 | Putative adenosine deaminase with a predicted role in nucleotide salvage pathways |
GBC41477.1 | g15490.t1 | RIR_2486000 | hypothetical protein | - | OG0000060 | YHL032C | 38.86 | 5.00E-120 | Glycerol kinase; converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p | AN3916 | 57.49 | 0 | Putative glycerol kinase with a predicted role in glycerol metabolism |
GBC41478.1 | g15491.t1 | RIR_2486100 | hypothetical protein | - | OG0000060 | - | - | - | - | AN0077 | 35.48 | 1.00E-49 | "Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity" |
GBC41479.1 | g15492.t1 | RIR_2486200 | hypothetical protein | - | OG0000060 | - | - | - | - | AN0077 | 34.94 | 1.00E-49 | "Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity" |
GBC41480.1 | g15493.t1 | RIR_2486300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41481.1 | g15494.t1 | RIR_2486400 | hypothetical protein | - | OG0005395 | YMR240C | 42.73 | 9.00E-52 | Protein required for assembly of U2 snRNP into the spliceosome; forms a complex with Hsh49p and Hsh155p | AN5098 | 49.47 | 2.00E-142 | "Ortholog(s) have U2 snRNP, post-mRNA release spliceosomal complex localization" |
GBC41482.1 | g15495.t1 | RIR_2486500 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41483.1 | g15496.t1 | RIR_2486600 | hypothetical protein | - | OG0000060 | - | - | - | - | - | - | - | - |
GBC41484.1 | g15497.t1 | RIR_2486700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41485.1 | JEMT01012293.1_cds_EXX76295.1_3733 | RIR_2486710 | JEMT01012293.1_cds_EXX76295.1_3733 | - | - | - | - | - | - | - | - | - | - |
GBC41486.1 | g15498.t1 | RIR_2486800 | "histone lysine methyltransferase, set, putative" | - | OG0000152 | - | - | - | - | - | - | - | - |
GBC41487.1 | g15499.t1 | RIR_2486900 | cyclin-dependent serine/threonine-protein kinase | - | OG0000057 | YBR164C | 73.18 | 1.00E-94 | "Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; role in membrane organization at trans-Golgi network; G protein of the Ras superfamily, similar to ADP-ribosylation factor" | AN5912 | 67.98 | 8.00E-88 | Predicted ADP ribosylation factor GTPase |
GBC41488.1 | g15499.t2 | RIR_2486900 | cyclin-dependent serine/threonine-protein kinase | - | OG0000057 | - | - | - | - | - | - | - | - |
GBC41489.1 | g15500.t1 | RIR_2487000 | Subunit ribosomal protein S15 | - | OG0003197 | - | - | - | - | - | - | - | - |
GBC41490.1 | g15501.t1 | RIR_2487100 | metalloendopeptidase | - | OG0001186 | YOR159C | 53.26 | 3.00E-27 | "Core Sm protein Sm E; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm E" | AN6735 | 56.47 | 1.00E-28 | "Ortholog(s) have splicing factor binding activity, role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, post-mRNA release spliceosomal complex localization" |
GBC41491.1 | g15502.t1 | RIR_2487200 | Putative dicarboxylic acid transmembrane | - | OG0000331 | YOL092W | 38.1 | 4.00E-51 | "Putative vacuolar membrane transporter for cationic amino acids; likely contributes to amino acid homeostasis by exporting cationic amino acids from the vacuole; member of the PQ-loop family, with seven transmembrane domains; similar to mammalian PQLC2 vacuolar transporter; YPQ1 has a paralog, RTC2, that arose from the whole genome duplication" | AN5720 | 31.19 | 4.00E-40 | Putative G-protein coupled receptor; has a PQ loop repeat |
GBC41492.1 | g15503.t1 | RIR_2487300 | hypothetical protein | - | - | YPL191C | 30.39 | 1.00E-34 | "Putative protein of unknown function; diploid deletion strain exhibits high budding index; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL191C has a paralog, YGL082W, that arose from the whole genome duplication" | AN8067 | 33.59 | 3.00E-30 | "Has domain(s) with predicted Lys48-specific deubiquitinase activity, thiol-dependent ubiquitin-specific protease activity" |
GBC41493.1 | g15504.t1 | RIR_2487400 | pb1 domain protein | - | OG0002091 | - | - | - | - | - | - | - | - |
GBC41494.1 | Tis13_85895 | RIR_2487410 | Tis13_85895 | - | - | - | - | - | - | - | - | - | - |
GBC41495.1 | g15505.t1 | RIR_2487500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41496.1 | g15506.t1 | RIR_2487600 | "upf0220-domain-containing protein, partial" | - | OG0001239 | - | - | - | - | - | - | - | - |
GBC41497.1 | g15507.t1 | RIR_2487700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41498.1 | g15508.t1 | RIR_2487800 | Ser/thr/tyr protein kinase | - | OG0000997 | - | - | - | - | - | - | - | - |
GBC41499.1 | Tis13_4941 | RIR_2487810 | Tis13_4941 | - | - | YDR170C | 31.73 | 2.00E-13 | "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles" | AN3438 | 32.1 | 2.00E-86 | "Has domain(s) with predicted ARF guanyl-nucleotide exchange factor activity, phospholipid binding activity and role in regulation of ARF protein signal transduction" |
GBC41500.1 | JEMT01012455.1_cds_EXX75328.1_4702 | RIR_2487820 | JEMT01012455.1_cds_EXX75328.1_4702 | - | - | - | - | - | - | - | - | - | - |
GBC41501.1 | g15509.t1 | RIR_2487900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41503.1 | Tis13_15348 | RIR_2488010 | Tis13_15348 | - | - | - | - | - | - | AN5278 | 39.42 | 3.00E-21 | "Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance" |
GBC41505.1 | g15512.t1 | RIR_2488200 | RNA recognition motif-containing protein | - | OG0000383 | - | - | - | - | - | - | - | - |
GBC41507.1 | g15514.t1 | RIR_2488400 | RNA-directed DNA polymerase from mobile element | - | OG0000001 | - | - | - | - | - | - | - | - |
GBC41509.1 | g15516.t1 | RIR_2488600 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41511.1 | Tis13_21851 | RIR_2488710 | Tis13_21851 | - | - | - | - | - | - | AN6767 | 36.63 | 6.00E-37 | Has domain(s) with predicted catalytic activity and role in metabolic process |
GBC41513.1 | g15519.t1 | RIR_2488900 | hypothetical protein | - | - | YPR013C | 53.45 | 1.00E-14 | Putative zinc finger protein; YPR013C is not an essential gene | AN8741 | 63.64 | 4.00E-21 | Putative C2H2 transcription factor involved in regulation of secondary metabolism and morphogenesis |
GBC41515.1 | g15521.t1 | RIR_2489100 | zinc finger bed domain-containing protein | - | OG0002170 | - | - | - | - | - | - | - | - |
GBC41516.1 | JEMT01026697.1_cds_EXX58565.1_21461 | RIR_2489110 | JEMT01026697.1_cds_EXX58565.1_21461 | - | - | YJL187C | 34.33 | 5.00E-31 | "Protein kinase that regulates the G2/M transition; regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; phosphorylates conserved tyrosine residue in N-terminus of Hsp90 in cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; homolog of S. pombe Wee1p; potential Cdc28p substrate" | AN5822 | 35.02 | 1.00E-37 | Serine/threonine protein kinase involved in DNA damage checkpoint and G2/M transition; ortholog of S. pombe wee1; inviable; arrests in cell cycle |
GBC41517.1 | g15522.t1 | RIR_2489200 | hypothetical protein | - | - | YKL014C | 23.55 | 5.00E-22 | Protein required for the normal accumulation of 25S and 5.8S rRNAs; nucleolar protein; associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit | AN0237 | 24.73 | 2.00E-30 | "Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus localization" |
GBC41518.1 | g15523.t2 | RIR_2489300 | hypothetical protein | - | - | YKL014C | 24.94 | 3.00E-18 | Protein required for the normal accumulation of 25S and 5.8S rRNAs; nucleolar protein; associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit | AN0237 | 26.21 | 2.00E-26 | "Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus localization" |
GBC41519.1 | g15523.t1 | RIR_2489300 | hypothetical protein | - | - | YKL014C | 23.55 | 6.00E-22 | Protein required for the normal accumulation of 25S and 5.8S rRNAs; nucleolar protein; associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit | AN0237 | 24.73 | 2.00E-30 | "Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus localization" |
GBC41520.1 | g15524.t1 | RIR_2489400 | protein-nucleus import-related protein | - | OG0002654 | - | - | - | - | - | - | - | - |
GBC41521.1 | g15525.t1 | RIR_2489500 | hypothetical protein | - | OG0000171 | YKL125W | 28.19 | 1.00E-23 | Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA; structure reveals unique HEAT repeat fold and a surface serine patch; phosphorylation of serine patch impairs cell growth and reduces RNA polymerase I binding in vitro and RNA polymerase I recruitment to the rDNA gene in vivo | AN0312 | 24.36 | 5.00E-44 | "Ortholog(s) have transcription factor activity, RNA polymerase I CORE element sequence-specific binding activity and role in transcription by RNA polymerase I" |
GBC41523.1 | g15527.t2 | RIR_2489700 | hypothetical protein | - | - | YBR237W | 26.75 | 2.00E-25 | "RNA helicase in the DEAD-box family; necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA" | AN1266 | 47.71 | 3.00E-95 | "Ortholog(s) have ATPase activity, U1 snRNP binding, U2 snRNP binding activity, role in U2-type prespliceosome assembly and U2-type prespliceosome localization" |
GBC41524.1 | g15527.t1 | RIR_2489700 | hypothetical protein | - | - | YBR237W | 46.59 | 5.00E-97 | "RNA helicase in the DEAD-box family; necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA" | AN1266 | 66.19 | 2.00E-152 | "Ortholog(s) have ATPase activity, U1 snRNP binding, U2 snRNP binding activity, role in U2-type prespliceosome assembly and U2-type prespliceosome localization" |
GBC41525.1 | g15528.t1 | RIR_2489800 | e3 ubiquitin-protein ligase rnf213-like | - | - | YCR059C | 43.8 | 1.00E-27 | Negative regulator of eIF2 kinase Gcn2p; competes with Gcn2p for binding to Gcn1p; may contribute to regulation of translation in response to starvation via regulation of Gcn2p; binds to monomeric actin and to ribosomes and polyribosomes; ortholog of mammalian IMPACT | AN8173 | 35.09 | 2.00E-32 | "Ortholog(s) have actin monomer binding, protein kinase inhibitor activity, ribosome binding activity, role in negative regulation of protein phosphorylation and polysome, ribosome localization" |
GBC41526.1 | g15529.t1 | RIR_2489900 | 5'-3' exoribonuclease 2 | - | OG0000732 | YCR059C | 43.8 | 1.00E-27 | Negative regulator of eIF2 kinase Gcn2p; competes with Gcn2p for binding to Gcn1p; may contribute to regulation of translation in response to starvation via regulation of Gcn2p; binds to monomeric actin and to ribosomes and polyribosomes; ortholog of mammalian IMPACT | AN8173 | 34.57 | 2.00E-32 | "Ortholog(s) have actin monomer binding, protein kinase inhibitor activity, ribosome binding activity, role in negative regulation of protein phosphorylation and polysome, ribosome localization" |
GBC41527.1 | g15530.t1 | RIR_2490000 | AAA family ATPase Rix7 (predicted) | - | OG0002808 | - | - | - | - | - | - | - | - |
GBC41528.1 | g15531.t1 | RIR_2490100 | sel1 repeat protein | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41529.1 | g15532.t1 | RIR_2490200 | Seryl-tRNA synthetase | - | OG0001825 | - | - | - | - | - | - | - | - |
GBC41530.1 | g15533.t1 | RIR_2490300 | 4-amino-4-deoxychorismate lyase | - | OG0004713 | YIL008W | 40.78 | 8.00E-19 | Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs; receives sulfur from the E1-like enzyme Uba4p and transfers it to tRNA; also functions as a protein tag with roles in nutrient sensing and oxidative stress response | AN12121 | 50.5 | 2.00E-31 | "Ortholog(s) have protein tag activity, role in cell budding, cellular response to oxidative stress, invasive growth in response to glucose limitation, protein urmylation, tRNA wobble position uridine thiolation and cytosol localization" |
GBC41531.1 | g15534.t1 | RIR_2490400 | Tartrate-resistant acid phosphatase type 5 | - | OG0003691 | - | - | - | - | AN2982 | 35.45 | 7.00E-84 | "Ortholog of A. niger CBS 513.88 : An02g12160, A. oryzae RIB40 : AO090005001426, Aspergillus wentii : Aspwe1_0135673, Aspergillus sydowii : Aspsy1_0042531 and Aspergillus terreus NIH2624 : ATET_01622" |
GBC41532.1 | g15535.t1 | RIR_2490500 | protein of unknown function | - | OG0000535 | - | - | - | - | AN2982 | 31.47 | 2.00E-55 | "Ortholog of A. niger CBS 513.88 : An02g12160, A. oryzae RIB40 : AO090005001426, Aspergillus wentii : Aspwe1_0135673, Aspergillus sydowii : Aspsy1_0042531 and Aspergillus terreus NIH2624 : ATET_01622" |
GBC41533.1 | g15536.t1 | RIR_2490600 | sel1 repeat-containing protein | - | OG0000000 | - | - | - | - | - | - | - | - |
GBC41534.1 | g15537.t1 | RIR_2490700 | umta methyltransferase family protein | - | OG0000025 | YDL091C | 27.04 | 2.00E-33 | Subunit of the DSC ubiquitin ligase complex; UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; ortholog of fission yeast Ucp10 | AN0770 | 32.98 | 9.00E-57 | "Ortholog(s) have clathrin binding activity, role in clathrin-dependent endocytosis, histone H2B ubiquitination, sterol regulatory element binding protein cleavage and Dsc E3 ubiquitin ligase complex, clathrin-coated vesicle localization" |
GBC41535.1 | g15538.t1 | RIR_2490800 | "GTPase imap family member 4-like, partial" | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41536.1 | g15539.t1 | RIR_2490900 | "GTPase imap family member 4-like, partial" | - | OG0000154 | - | - | - | - | - | - | - | - |
GBC41537.1 | g15540.t1 | RIR_2491000 | polyglutamine-binding protein 1 | - | OG0006450 | - | - | - | - | - | - | - | - |
GBC41538.1 | g15541.t1 | RIR_2491100 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41539.1 | g15542.t1 | RIR_2491200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41540.1 | g15542.t2 | RIR_2491200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41541.1 | Tis13_333948 | RIR_2491210 | Tis13_333948 | - | - | - | - | - | - | - | - | - | - |
GBC41542.1 | g15543.t1 | RIR_2491300 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41543.1 | g15544.t1 | RIR_2491400 | "mata_hmg, partial" | - | - | - | - | - | - | - | - | - | - |
GBC41544.1 | g15545.t1 | RIR_2491500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41545.1 | JEMT01028476.1_cds_EXX54504.1_25533 | RIR_2491510 | JEMT01028476.1_cds_EXX54504.1_25533 | - | OG0006393 | - | - | - | - | - | - | - | - |
GBC41546.1 | g15546.t1 | RIR_2491600 | "mata_hmg, partial" | - | - | - | - | - | - | - | - | - | - |
GBC41547.1 | g15547.t1 | RIR_2491700 | "mata_hmg, partial" | - | - | - | - | - | - | - | - | - | - |
GBC41548.1 | g15548.t1 | RIR_2491800 | "mata_hmg, partial" | - | - | YOL034W | 28.07 | 1.00E-112 | Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; binds single-stranded DNA and has ATPase activity; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair | AN8742 | 32.91 | 1.00E-165 | "Ortholog(s) have ATPase activity, SUMO transferase activity, damaged DNA binding, single-stranded DNA binding activity" |
GBC41549.1 | g15549.t1 | RIR_2491900 | mating type protein mat1-2-1 | - | OG0000027 | - | - | - | - | - | - | - | - |
GBC41550.1 | g15550.t1 | RIR_2492000 | zinc finger bed domain-containing protein | - | - | - | - | - | - | - | - | - | - |
GBC41551.1 | g15551.t1 | RIR_2492100 | kelch-like protein 17 | - | OG0000006 | - | - | - | - | - | - | - | - |
GBC41552.1 | g15552.t1 | RIR_2492200 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41555.1 | JEMT01022730.1_cds_EXX64878.1_15151 | RIR_2492320 | JEMT01022730.1_cds_EXX64878.1_15151 | - | - | - | - | - | - | - | - | - | - |
GBC41556.1 | g15554.t1 | RIR_2492400 | hypothetical protein | - | OG0000036 | - | - | - | - | - | - | - | - |
GBC41557.1 | g15555.t1 | RIR_2492500 | Calmodulin-dependent protein kinase I | - | OG0000216 | - | - | - | - | - | - | - | - |
GBC41558.1 | g15556.t1 | RIR_2492600 | T-complex protein 1 subunit epsilon | - | OG0001694 | - | - | - | - | - | - | - | - |
GBC41559.1 | g15557.t1 | RIR_2492700 | T-complex protein 1 subunit epsilon | - | OG0001694 | - | - | - | - | - | - | - | - |
GBC41560.1 | g15558.t2 | RIR_2492800 | Translation elongation facter 1-alpha | - | OG0000253 | - | - | - | - | - | - | - | - |
GBC41561.1 | g15558.t1 | RIR_2492800 | Translation elongation facter 1-alpha | - | OG0000253 | - | - | - | - | - | - | - | - |
GBC41562.1 | g15559.t1 | RIR_2492900 | Acyl-CoA oxidase | - | OG0008281 | - | - | - | - | - | - | - | - |
GBC41568.1 | g15562.t1 | RIR_2493200 | RNA-binding protein | - | OG0004618 | YDR091C | 72.19 | 0 | "Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress" | AN1256 | 71.83 | 0 | "Has domain(s) with predicted ATP binding, ATPase activity, nucleoside-triphosphatase activity, nucleotide binding activity" |
GBC41573.1 | g15567.t1 | RIR_2493700 | Ubiquitin conjugating enzyme E2 | - | OG0001894 | YBR222C | 29.69 | 2.00E-24 | "Oxalyl-CoA synthetase; capable of catalyzing conversion of oxalate to oxalyl-CoA; catalyzes first step in pathway of oxalate degradation that functions to protect yeast from inhibitory effects of oxalate; peroxisomal protein that binds mRNA; localizes to both peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid; similar to E. coli long chain acyl-CoA synthetase" | AN0398 | 37.85 | 2.00E-53 | Has domain(s) with predicted catalytic activity and role in metabolic process |
GBC41574.1 | g15568.t1 | RIR_2493800 | zinc metalloprotease | - | OG0003386 | - | - | - | - | - | - | - | - |
GBC41575.1 | g15569.t1 | RIR_2493900 | putative phosphatidylglycerol/ | - | OG0000621 | - | - | - | - | - | - | - | - |
GBC41576.1 | g15570.t1 | RIR_2494000 | "alpha-1,3-mannosyltransferase cmt1" | GT69 | OG0003528 | YFL021W | 39.38 | 1.00E-22 | Transcriptional activator of nitrogen catabolite repression genes; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p; different translational starts produce two major and two minor isoforms that are differentially regulated and localized | AN6221 | 62.12 | 5.00E-20 | "Putative GATA zinc finger transcription factor; leucine zipper motif; negative regulator of nitrogen catabolism; locus is predicted to encode areB-alpha, -beta, and -gamma transcripts" |
GBC41577.1 | g15571.t1 | RIR_2494100 | transcription regulator gcr1 | - | OG0005777 | - | - | - | - | AN3487 | 25.44 | 2.00E-22 | "Ortholog of Aspergillus brasiliensis : Aspbr1_0190075, Aspergillus acidus : Aspfo1_0188967, Aspergillus wentii : Aspwe1_0067338 and Aspergillus versicolor : Aspve1_0158008" |
GBC41578.1 | JEMT01017847.1_cds_EXX67320.1_12710 | RIR_2494110 | JEMT01017847.1_cds_EXX67320.1_12710 | - | - | - | - | - | - | - | - | - | - |
GBC41580.1 | g15572.t1 | RIR_2494200 | crinkler family protein | - | - | - | - | - | - | AN11074 | 24 | 4.00E-12 | Predicted hAT transposon-related ORF |
GBC41582.1 | JEMT01015914.1_cds_EXX71809.1_8212 | RIR_2494220 | JEMT01015914.1_cds_EXX71809.1_8212 | - | - | - | - | - | - | - | - | - | - |
GBC41583.1 | g15573.t1 | RIR_2494300 | thiamin pyrophosphokinase-related protein | - | OG0002257 | - | - | - | - | - | - | - | - |
GBC41584.1 | g15574.t1 | RIR_2494400 | adenine/adenosine deaminase | - | OG0002009 | - | - | - | - | - | - | - | - |
GBC41585.1 | g15575.t1 | RIR_2494500 | Glycerol kinase | - | OG0000521 | - | - | - | - | - | - | - | - |
GBC41586.1 | g15576.t2 | RIR_2494600 | "oxidoreductase, 2og-Fe(II) oxygenase family" | - | OG0000412 | - | - | - | - | - | - | - | - |
GBC41587.1 | g15576.t1 | RIR_2494600 | "oxidoreductase, 2og-Fe(II) oxygenase family" | - | OG0000412 | - | - | - | - | - | - | - | - |
GBC41588.1 | g15577.t1 | RIR_2494700 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41589.1 | g15578.t1 | RIR_2494800 | Splicing factor 3B subunit 2 | - | OG0002548 | - | - | - | - | - | - | - | - |
GBC41590.1 | g15579.t1 | RIR_2494900 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41591.1 | g15580.t1 | RIR_2495000 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41592.1 | g15581.t1 | RIR_2495100 | cardiolipin synthase | - | - | - | - | - | - | - | - | - | - |
GBC41593.1 | g15582.t1 | RIR_2495200 | serine/threonine protein kinase | - | - | YFR024C-A | 50 | 1.00E-53 | "Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication" | AN4168 | 49.76 | 5.00E-63 | "Ortholog of A. fumigatus Af293 : Afu6g07880, A. niger CBS 513.88 : An11g02770, A. oryzae RIB40 : AO090003000147, Aspergillus wentii : Aspwe1_0121458 and Aspergillus sydowii : Aspsy1_1067771" |
GBC41595.1 | g15583.t1 | RIR_2495300 | "ADP-ribosylation factor, Arf family" | - | OG0000116 | - | - | - | - | AN11377 | 61.76 | 4.00E-28 | Has domain(s) with predicted NADH dehydrogenase (ubiquinone) activity and mitochondrion localization |
GBC41596.1 | g15584.t1 | RIR_2495400 | hypothetical protein | - | OG0002949 | YLR298C | 43.75 | 7.00E-11 | "Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site" | AN1951 | 65.08 | 2.00E-24 | "Has domain(s) with predicted nucleic acid binding, zinc ion binding activity" |
GBC41597.1 | g15585.t1 | RIR_2495500 | hypothetical protein | - | - | - | - | - | - | - | - | - | - |
GBC41598.1 | g15586.t1 | RIR_2495600 | Small nuclear ribonucleoprotein E | - | OG0002486 | - | - | - | - | - | - | - | - |
GBC41599.1 | g15587.t1 | RIR_2495700 | vacuolar membrane pq loop repeat protein | - | OG0000485 | YMR205C | 45.58 | 0 | "Beta subunit of heterooctameric phosphofructokinase; involved in glycolysis; indispensable for anaerobic growth; activated by fructose-2,6-bisphosphate and AMP; mutation inhibits glucose induction of cell cycle-related genes" | AN3223 | 55.87 | 0 | Putative 6-phosphofructokinase with a predicted role in gluconeogenesis and glycolysis; upregulated under hypoxic growth conditions |
GBC41600.1 | g15588.t1 | RIR_2495800 | duf544 family protein | - | OG0002423 | YDR517W | 31.07 | 1.00E-16 | "Acetylated cis-Golgi protein, involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes; protein abundance increases in response to DNA replication stress" | - | - | - | - |
GBC41601.1 | g15589.t1 | RIR_2495900 | hypothetical protein | - | OG0006142 | YPL140C | 53.33 | 8.00E-97 | "MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication" | AN4189 | 49.83 | 8.00E-93 | "Essential mitogen-activated protein kinase kinase (MAPKK); mutants arrest as branched germlings, but the phenotype is remediated by NaCl or sucrose" |
GBC41603.1 | g15590.t1 | RIR_2496000 | putative zinc finger domain-containing protein | - | OG0000011 | - | - | - | - | AN5998 | 31.58 | 9.00E-31 | Has domain(s) with predicted zinc ion binding activity |
GBC41604.1 | Tis13_95017 | RIR_2496010 | Tis13_95017 | - | - | - | - | - | - | AN3464 | 47.93 | 1.00E-72 | Has domain(s) with predicted protein-L-isoaspartate (D-aspartate) O-methyltransferase activity and role in cellular protein modification process |
GBC41605.1 | Tis13_29784 | RIR_2496020 | Tis13_29784 | - | - | YBR111C | 40.11 | 6.00E-43 | Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate | AN7711 | 41.92 | 1.00E-46 | Putative nudix hydrolase |
GBC41606.1 | JEMT01027925.1_cds_EXX55907.1_24119 | RIR_2496030 | JEMT01027925.1_cds_EXX55907.1_24119 | - | - | YPL164C | 29.55 | 4.00E-35 | Protein involved in DNA mismatch repair and meiotic recombination; involved in crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability | AN4365 | 34.18 | 5.00E-40 | "Ortholog(s) have role in meiotic mismatch repair, reciprocal meiotic recombination and MutLgamma complex, nucleus localization" |
GBC41607.1 | g15591.t1 | RIR_2496100 | guanine nucleotide exchange factor | - | OG0000181 | - | - | - | - | - | - | - | - |
GBC41608.1 | g15592.t1 | RIR_2496200 | serine/threonine protein kinase | - | - | - | - | - | - | AN9495 | 23.08 | 9.00E-12 | "Has domain(s) with predicted DNA binding, nucleic acid binding activity" |
GBC41609.1 | g15593.t1 | RIR_2496300 | ATP-dependent DNA helicase pif1-like | - | OG0000037 | YPL240C | 68.13 | 0 | "Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication" | AN8269 | 70.35 | 0 | "90 kilodalton heat shock protein; physically associates with importin-alpha, KapA; palA-dependent expression independent of pH" |
GBC41610.1 | g15594.t1 | RIR_2496400 | ATP-dependent DNA helicase pif1-like | - | OG0005329 | - | - | - | - | - | - | - | - |
GBC41611.1 | g15595.t1 | RIR_2496500 | transcriptional factor b3 | - | OG0000062 | YGL232W | 30.29 | 2.00E-34 | Putative tRNA acetyltransferase; RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA; protein abundance increases in response to DNA replication stress | AN4889 | 31.25 | 4.00E-36 | Ortholog(s) have RNA binding activity and role in tRNA modification |
GBC41612.1 | g15596.t1 | RIR_2496600 | hypothetical protein | - | OG0000026 | YPR162C | 22.88 | 6.00E-11 | "Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; ORC4 has a paralog, RIF2, that arose from the whole genome duplication" | AN5892 | 22.41 | 2.00E-29 | "Ortholog(s) have DNA replication origin binding activity and role in DNA replication initiation, chromatin silencing at silent mating-type cassette, pre-replicative complex assembly involved in nuclear cell cycle DNA replication" |
GBC41613.1 | JEMT01022854.1_cds_EXX64751.1_15277 | RIR_2496610 | JEMT01022854.1_cds_EXX64751.1_15277 | - | OG0000026 | YLR086W | 43.41 | 0 | "Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate" | AN4597 | 53.67 | 0 | "Putative condensin subunit, ortholog S. cerevisiae Smc4p" |
GBC41616.1 | g15599.t1 | RIR_2496900 | hypothetical protein | - | OG0000062 | YNL116W | 47.53 | 3.00E-61 | "Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication" | AN6908 | 35.84 | 9.00E-46 | "Ortholog of A. fumigatus Af293 : Afu5g13560, A. niger CBS 513.88 : An14g05050, A. oryzae RIB40 : AO090113000013, Aspergillus wentii : Aspwe1_0452655 and Aspergillus sydowii : Aspsy1_0589528" |
GBC41618.1 | g15601.t1 | RIR_2497100 | "os11g0671600, partial" | - | OG0000062 | - | - | - | - | AN3643 | 22.67 | 5.00E-35 | "Ortholog(s) have guanyl-nucleotide exchange factor activity, role in Golgi to endosome transport, endocytosis, protein targeting to vacuole and early endosome membrane, extrinsic component of membrane, trans-Golgi network localization" |
GBC41619.1 | g15602.t1 | RIR_2497200 | enoyl-coa hydratase/isomerase family protein | - | OG0004738 | YNL297C | 28.65 | 4.00E-48 | Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins | AN3643 | 35.62 | 4.00E-101 | "Ortholog(s) have guanyl-nucleotide exchange factor activity, role in Golgi to endosome transport, endocytosis, protein targeting to vacuole and early endosome membrane, extrinsic component of membrane, trans-Golgi network localization" |
GBC41620.1 | g15603.t1 | RIR_2497300 | Nuclear receptor interaction protein | - | OG0001499 | YNL297C | 28.65 | 5.00E-48 | Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins | AN3643 | 35.62 | 3.00E-101 | "Ortholog(s) have guanyl-nucleotide exchange factor activity, role in Golgi to endosome transport, endocytosis, protein targeting to vacuole and early endosome membrane, extrinsic component of membrane, trans-Golgi network localization" |
GBC41621.1 | g15604.t1 | RIR_2497400 | c2h2 finger domain protein | - | OG0000003 | YNL297C | 31.89 | 2.00E-33 | Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins | AN3643 | 37.25 | 2.00E-43 | "Ortholog(s) have guanyl-nucleotide exchange factor activity, role in Golgi to endosome transport, endocytosis, protein targeting to vacuole and early endosome membrane, extrinsic component of membrane, trans-Golgi network localization" |
GBC41622.1 | g15605.t1 | RIR_2497500 | anaphase promoting complex subunit 2 | - | OG0003110 | - | - | - | - | AN9192 | 35.11 | 6.00E-42 | "Ortholog of A. fumigatus Af293 : Afu3g03910, A. niger CBS 513.88 : An13g01790, A. oryzae RIB40 : AO090038000138, Neosartorya fischeri NRRL 181 : NFIA_006190 and Aspergillus kawachii : Aspka1_0177086" |
GBC41623.1 | g15605.t2 | RIR_2497500 | anaphase promoting complex subunit 2 | - | OG0003110 | YCR084C | 46.84 | 4.00E-119 | "General repressor of transcription; forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes" | AN6505 | 67.22 | 1.00E-171 | "WD40 repeat protein; required for sexual development and for sterigmatocystin production; experimentally studied orthologs present in Neurospora crassa, Candida albicans, Schizosaccharomyces pombe and Penicillium marneffei" |