home > Gene Annotation List

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NCBI IDProteinIDLocusTagProductIDCazyIDOrthGroupIDSGD IDidentevalAnnotationASpGD IDidentEvalAnnotation
GBC12571.1g4279.t1RIR_0143500transposable element tc3 transposase-OG0000005----AN1032931.123.00E-44Predicted mariner transposon-related ORF
GBC12572.1g4280.t1RIR_0143600zinc finger bed domain-containing protein 4-like----------
GBC12573.1g4281.t1RIR_0143700hypothetical protein----------
GBC12575.1JEMT01025281.1_cds_EXX61568.1_18461RIR_0143810JEMT01025281.1_cds_EXX61568.1_18461----------
GBC12576.1g4283.t1RIR_0143900protein far1-related sequence 11-like-OG0000030--------
GBC12577.1g4284.t1RIR_0144000zinc metalloproteinase nas-7-like-OG0001265--------
GBC12578.1g4285.t1RIR_0144100ribonuclease hi-OG0000001--------
GBC12580.1g16319.t1RIR_0144300hypothetical protein-OG0000002--------
GBC12581.1g16320.t1RIR_0144400hypothetical protein-OG0001061--------
GBC12584.1g16323.t1RIR_0144700ran GTPase-activating protein 1-OG0000561----AN486227.162.00E-15Putative Ran GTPase activating protein (GAP) with homology to Saccharomyces cerevisiae Rna1p; endogenously tagged RanGAP is excluded from nuclei during interphase and disperses throughout the cell at mitosis
GBC12588.1g16326.t1RIR_0145000hypothetical protein----------
GBC12589.1g16327.t1RIR_0145100hypothetical protein----------
GBC12590.1g16327.t2RIR_0145100hypothetical protein----------
GBC12591.1Tis13_97833RIR_0145110Tis13_97833----------
GBC12593.1g16328.t1RIR_0145200hypothetical protein----------
GBC12594.1g16329.t1RIR_0145300transposase domain-containing protein-OG0000002--------
GBC12596.1g16331.t1RIR_0145500zinc finger bed domain-containing protein-OG0000008--------
GBC12597.1g16332.t1RIR_0145600hypothetical protein-OG0000008----AN1107432.195.00E-21Predicted hAT transposon-related ORF
GBC12599.1g16334.t1RIR_0145800RNA-directed DNA polymerase from mobile element-OG0000001----AN036827.491.00E-12"Has domain(s) with predicted RNA binding, RNA-DNA hybrid ribonuclease activity, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in RNA-dependent DNA biosynthetic process"
GBC12602.1g16337.t1RIR_0146100reverse transcriptase-OG0000001----AN864826.86.00E-12"Has domain(s) with predicted RNA binding, RNA-DNA hybrid ribonuclease activity, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in RNA-dependent DNA biosynthetic process"
GBC12604.1g16339.t1RIR_0146300zinc finger bed domain-containing protein-OG0000008----AN1107426.224.00E-13Predicted hAT transposon-related ORF
GBC12605.1g16340.t1RIR_0146400hypothetical protein----------
GBC12607.1g16342.t1RIR_0146600RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC12610.1g16345.t1RIR_0146900hypothetical protein----------
GBC12612.1g16347.t1RIR_0147100probable RNA-directed DNA polymerase from-OG0000001--------
GBC12614.1g16349.t1RIR_0147300hypothetical protein----------
GBC12615.1g16350.t1RIR_0147400endonuclease-OG0000001----AN036825.934.00E-11"Has domain(s) with predicted RNA binding, RNA-DNA hybrid ribonuclease activity, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in RNA-dependent DNA biosynthetic process"
GBC12617.1g16352.t1RIR_0147600zinc finger bed domain-containing protein----------
GBC12618.1g16353.t1RIR_0147700hypothetical protein----------
GBC12619.1g16354.t1RIR_0147800Fructose-bisphosphate aldolase Fba1-OG0002006YKL060C58.574.00E-156"Fructose 1,6-bisphosphate aldolase; required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress; N-terminally propionylated in vivo"AN287565.172.00E-169"Putative fructose-bisphosphate aldolase with a predicted role in gluconeogenesis and glycolysis; intracellular, menadione stress-induced protein; palA-dependent expression independent of pH"
GBC12620.1g16355.t1RIR_0147900CLASP family microtubule-associated protein-OG0000894YBL034C25.97.00E-17Component of the mitotic spindle; binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle polesAN099523.931.00E-26"Ortholog of A. fumigatus Af293 : Afu1g12700, A. oryzae RIB40 : AO090012000643, Aspergillus wentii : Aspwe1_0051357, Aspergillus sydowii : Aspsy1_0083776 and Aspergillus terreus NIH2624 : ATET_00461"
GBC12621.1g16356.t1RIR_0148000Conserved oligomeric golgi complex subunit 8-OG0003028----AN1177226.913.00E-22Has domain(s) with predicted Golgi transport complex localization
GBC12622.1g16357.t1RIR_0148100hypothetical protein----------
GBC12623.1g16358.t1RIR_0148200Lignostilbene dioxygenase protein-OG0000996----AN170425.596.00E-44Ortholog(s) have role in xanthophyll metabolic process
GBC12624.1g16359.t1RIR_0148300karyopherin kap113-OG0002466YPL125W28.571.00E-102Karyopherin responsible for the nuclear import of Rpf1p; Rpf1p is a ribosome maturation factorAN405328.531.00E-119"Ortholog(s) have nuclear localization sequence binding, protein transporter activity and role in cellular response to drug, poly(A)+ mRNA export from nucleus, protein import into nucleus"
GBC12625.1g16360.t2RIR_0148400hypothetical protein----------
GBC12626.1g16360.t1RIR_0148400hypothetical protein----------
GBC12627.1g16361.t1RIR_0148500UDP-n-acetylglucosaminyltransferaseGT41OG0003639----AN026543.324.00E-141"Ortholog of A. fumigatus Af293 : Afu1g03380, A. niger CBS 513.88 : An01g04760, A. oryzae RIB40 : AO090005000763, Aspergillus wentii : Aspwe1_0049645 and Aspergillus sydowii : Aspsy1_0027812"
GBC12628.1Tis13_46992RIR_0148510Tis13_46992-OG0000037----AN527845.335.00E-16"Has domain(s) with predicted ATP binding, DNA helicase activity, helicase activity and role in DNA repair, telomere maintenance"
GBC12629.1g16362.t1RIR_0148600zinc finger cchc domain-containing protein 13-OG0003761--------
GBC12630.1JEMT01023753.1_cds_EXX63840.1_16188RIR_0148610JEMT01023753.1_cds_EXX63840.1_16188----------
GBC12634.1JEMT01027887.1_cds_EXX56031.1_24004RIR_0148810JEMT01027887.1_cds_EXX56031.1_24004----------
GBC12637.1g16367.t1RIR_0149100ubiquitin fusion degradation protein-OG0004707YGR048W30.594.00E-22"Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; polyubiquitin binding protein that assists in the dislocation of misfolded, ERAD substrates that are subsequently delivered to the proteasome for degradation; involved in regulated destruction of ER membrane proteins such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p); involved in mobilizing membrane bound transaction factors by regulated Ub/proteasome-dependent processing (RUP)"AN1087730.967.00E-110Has domain(s) with predicted role in ubiquitin-dependent protein catabolic process
GBC12638.1g16367.t2RIR_0149100ubiquitin fusion degradation protein-OG0004707YGR048W30.593.00E-22"Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; polyubiquitin binding protein that assists in the dislocation of misfolded, ERAD substrates that are subsequently delivered to the proteasome for degradation; involved in regulated destruction of ER membrane proteins such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p); involved in mobilizing membrane bound transaction factors by regulated Ub/proteasome-dependent processing (RUP)"AN1087730.233.00E-105Has domain(s) with predicted role in ubiquitin-dependent protein catabolic process
GBC12639.1g16368.t1RIR_0149200Inositol-polyphosphate 5-phosphatase-OG0000125YOR109W31.016.00E-40"Polyphosphatidylinositol phosphatase; dephosphorylates multiple phosphatidylinositol phosphates; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains; INP53 has a paralog, INP52, that arose from the whole genome duplication"AN828827.752.00E-36"Ortholog(s) have calcium ion binding, inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity and inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity, more"
GBC12640.1g16369.t1RIR_0149300hypothetical protein-OG0000058--------
GBC12641.1g16370.t1RIR_0149400ubiquitin system component cue-OG0000432----AN655128.372.00E-143Has domain(s) with predicted ATP binding activity
GBC12642.1g16371.t1RIR_0149500ubiquitin system component cue-OG0000432----AN6551401.00E-50Has domain(s) with predicted ATP binding activity
GBC12643.1Tis13_85585RIR_0149510Tis13_85585----------
GBC12644.1g16372.t1RIR_0149600"Ammonium transporter, Amt family"-OG0000546YNL142W44.676.00E-125Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulationAN118158.595.00E-175Putative transporter with a predicted role in small molecule transport; ammonium permease
GBC12645.1g16373.t1RIR_0149700MRP family ATP-binding protein-OG0003533YIL003W38.721.00E-52Highly conserved iron-sulfur cluster binding protein; localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosolAN752547.045.00E-96"Ortholog of A. fumigatus Af293 : Afu6g09810, A. niger CBS 513.88 : An11g07690, A. oryzae RIB40 : AO090001000614, Aspergillus wentii : Aspwe1_0045811 and Aspergillus sydowii : Aspsy1_0045889"
GBC12646.1g16374.t1RIR_0149800Dipeptidyl-peptidase 5CE10OG0001988--------
GBC12647.1g16375.t1RIR_0149900nudix family hydrolase-OG0004694----AN1063630.291.00E-42Has domain(s) with predicted hydrolase activity
GBC12648.1g16376.t1RIR_0150000Mitochondrial fusion and transport protein UGO1-OG0001813--------
GBC12649.1g16377.t1RIR_0150100Cleavage and polyadenylation specificity factor-OG0002329YLR115W33.332.00E-47"Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein."AN308231.781.00E-51Ortholog(s) have mRNA cleavage and polyadenylation specificity factor complex localization
GBC12650.1g16378.t1RIR_0150200hypothetical protein----------
GBC12651.1g16379.t1RIR_0150300tigr01458 family had hydrolase-OG0004212--------
GBC12652.1g16380.t2RIR_0150400Dnaj chaperone protein-OG0001433YFL016C34.718.00E-50Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperonesAN1077838.263.00E-80Ortholog(s) have mitochondrion localization
GBC12653.1g16380.t1RIR_0150400Dnaj chaperone protein-OG0001433YFL016C35.197.00E-50Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperonesAN1077838.352.00E-80Ortholog(s) have mitochondrion localization
GBC12654.1g16381.t1RIR_0150500Endoplasmic reticulum translocation complex-OG0003078YBR171W25.527.00E-11"Non-essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec63p, Sec62p, and Sec72p"AN144243.235.00E-39"Ortholog(s) have protein transporter activity, role in filamentous growth, posttranslational protein targeting to membrane, translocation and Sec62/Sec63 complex localization"
GBC12655.1g16382.t1RIR_0150600AP endonuclease 1-OG0001095----AN473626.939.00E-19"Ortholog(s) have DNA-(apurinic or apyrimidinic site) endonuclease activity, double-stranded DNA 3'-5' exodeoxyribonuclease activity, phosphodiesterase I activity"
GBC12656.1g16383.t1RIR_0150700ring/u-box-OG0000311YKR017C26.57.00E-12RING finger ubiquitin ligase (E3); involved in ubiquitylation and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU)AN368930.33.00E-22Ortholog(s) have site of double-strand break localization
GBC12657.1g16383.t2RIR_0150700ring/u-box-OG0000311YKR017C26.55.00E-12RING finger ubiquitin ligase (E3); involved in ubiquitylation and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU)AN368930.33.00E-22Ortholog(s) have site of double-strand break localization
GBC12658.1g16384.t1RIR_0150800Ubiquitin C-OG0000122YLL039C44.446.00E-30"Ubiquitin; becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats; protein abundance increases in response to DNA replication stress"AN200044.447.00E-30"Polyubiquitin, contains four head to tail repeats of ubiqiutin; transcript upregulated in response to camptothecin"
GBC12659.1g16385.t1RIR_0150900hypothetical protein-OG0000917--------
GBC12660.1g16386.t1RIR_0151000MAP kinase kinase kinase Ste11-OG0000572YLR362W35.936.00E-123"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress"AN226959.734.00E-115"Mitogen-activated protein kinase kinase (MAPKK), component of a signaling module SteD-SteC-MkkB-MpkB that controls coordination of development and secondary metabolism; mutant has a moderate growth defect and arrested sexual development"
GBC12661.1g16387.t1RIR_0151100ccaat-binding factor subunit b-OG0000972YGL237C57.332.00E-22Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA bindingAN754557.51.00E-22Component of AnCP/AnCF CCAAT-binding complex; hapB mRNA is negatively regulated by AnCP/AnCF complex
GBC12666.1g16390.t1RIR_0151400hypothetical protein----------
GBC12667.1g16391.t1RIR_0151500-D/NADH kinase-OG0000424YJR049C42.547.00E-106"ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p); UTR1 has a paralog, YEF1, that arose from the whole genome duplication"AN766652.769.00E-144"Ortholog(s) have NAD+ kinase activity, NADH kinase activity and role in NADP biosynthetic process, cellular iron ion homeostasis"
GBC12669.1g16392.t1RIR_0151600zinc finger bed domain-containing protein-OG0000008--------
GBC12670.1g16393.t1RIR_0151700hypothetical protein----------
GBC12671.1g16394.t1RIR_0151800ADP-ribose pyrophosphatase-OG0000004--------
GBC12672.1g16395.t1RIR_0151900retrotransposable element-OG0000004YIL082W-A38.872.00E-52"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547034.661.00E-47Predicted gypsy transposon-related ORF
GBC12673.1g16396.t1RIR_0152000retrotransposable element-OG0000004YIL082W-A26.583.00E-17"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN1064927.952.00E-22"Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process"
GBC12674.1JEMT01028494.1_cds_EXX54357.1_25670RIR_0152010JEMT01028494.1_cds_EXX54357.1_25670----------
GBC12675.1g16397.t1RIR_0152100hypothetical protein----------
GBC12676.1g16398.t1RIR_0152200camp-dependent protein kinase catalytic subunit-OG0000080--------
GBC12677.1g16399.t1RIR_0152300duf659 and ribonuclease h-like domain containing----------
GBC12681.1g16403.t1RIR_0152700hypothetical protein----------
GBC12682.1g16404.t1RIR_0152800hypothetical protein-OG0000077--------
GBC12685.1g16407.t1RIR_0153100flagellar calcium-binding protein-like----------
GBC12686.1Tis13_343695RIR_0153110Tis13_343695----------
GBC12687.1g16408.t1RIR_0153200pap2-domain-containing protein-OG0001643--------
GBC12688.1g16409.t1RIR_0153300Mitochondrial metalloendopeptidase (predicted)-OG0003640YDR430C40.610Lysine-specific metalloprotease of the pitrilysin family; metalloprotease of the intermembrane space; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphologyAN385340.140Pitrilysin family metalloprotease; protein induced by farnesol
GBC12689.1g16410.t1RIR_0153400hypothetical protein----------
GBC12690.1g16411.t1RIR_0153500hypothetical protein----------
GBC12691.1JEMT01027520.1_cds_EXX56797.1_23227RIR_0153510JEMT01027520.1_cds_EXX56797.1_23227----------
GBC12692.1g16412.t1RIR_0153600ribonuclease hi----------
GBC12693.1g16413.t1RIR_0153700hypothetical protein-OG0000929--------
GBC12694.1g16414.t1RIR_0153800hypothetical protein-OG0000929--------
GBC12698.1g16418.t1RIR_0154200RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC12702.1g16422.t1RIR_0154600putative nuclease harbi1-OG0000579--------
GBC12704.1g16424.t1RIR_0154800hypothetical protein----------
GBC12705.1g16425.t1RIR_0154900probable RNA-directed DNA polymerase from-OG0000001--------
GBC12706.1g16426.t1RIR_0155000hypothetical protein----------
GBC12707.1g16427.t1RIR_0155100zinc finger bed domain-containing protein-OG0000077--------
GBC12708.1g16428.t1RIR_0155200exodeoxyribonuclease III----------
GBC12712.1g16432.t1RIR_0155600delta-actitoxin-ate1a-like----------
GBC12713.1g16433.t1RIR_0155700CENP-b protein 1-OG0000010YDR081C24.622.00E-12Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditionsAN871729.153.00E-43"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC12714.1g16434.t1RIR_0155800ribonuclease h-like protein-OG0000008--------
GBC12715.1g16435.t1RIR_0155900"hat family dimerization protein, partial"----------
GBC12716.1g16436.t1RIR_0156000protein far1-related sequence 5-like-OG0000030--------
GBC12717.1Tis13_33059RIR_0156010Tis13_33059----------
GBC12718.1g16437.t1RIR_0156100hypothetical protein----------
GBC12719.1g16438.t1RIR_0156200collagen triple helix repeat proteinCBM19OG0001323--------
GBC12720.1g16439.t1RIR_0156300hypothetical protein----------
GBC12721.1g16440.t1RIR_0156400trka-n domain dehydrogenase-OG0004461--------
GBC12722.1g16441.t1RIR_0156500Rad3/XPD DNA repair helicase-OG0001885YER171W65.1605' to 3' DNA helicase; involved in nucleotide excision repair and transcription; subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stressAN943668.510"Ortholog(s) have ATP-dependent 5'-3' DNA helicase activity, damaged DNA binding activity"
GBC12723.1g16442.t1RIR_0156600Serine/threonine-protein phosphatase PPG1-OG0000251YNR032W66.021.00E-119"Putative serine/threonine protein phosphatase; putative phosphatase of the type 2A-like phosphatase family, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases"AN016479.18.00E-160Protein phosphatase; reduced growth on AVICEL medium and reduced eglA and eglB expression
GBC12724.1g16443.t2RIR_0156700MED6 RNA polymerase II transcriptional-OG0001845YHR058C29.92.00E-26Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein abundance increases in response to DNA replication stressAN654936.812.00E-22"Ortholog(s) have RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly, protein kinase activator activity"
GBC12725.1g16443.t1RIR_0156700MED6 RNA polymerase II transcriptional-OG0001845YHR058C29.92.00E-26Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein abundance increases in response to DNA replication stressAN654936.812.00E-22"Ortholog(s) have RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly, protein kinase activator activity"
GBC12726.1g16444.t1RIR_01568003-ketodihydrosphingosine reductase tsc10-OG0001332YBR265W29.554.00E-293-ketosphinganine reductase; catalyzes the second step in phytosphingosine synthesis; essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine; localized to lipid droplets; member of short chain dehydrogenase/reductase protein familyAN116530.191.00E-47Putative 3-dehydrosphinganine reductase with a predicted role in sphingoglycolipid metabolism
GBC12727.1g16445.t1RIR_0156900Molybdenum cofactor biosynthesis protein-OG0003505----AN377845.471.00E-179Putative Gephyrin-related protein involved in molybdenum cofactor biosynthesis; molybdopterin cofactor required for the activity of nitrate reductase
GBC12728.1g16446.t1RIR_0157000MAP kinase kinase kinase Ste11-OG0000572YLR362W40.072.00E-130"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress"AN226937.113.00E-152"Mitogen-activated protein kinase kinase (MAPKK), component of a signaling module SteD-SteC-MkkB-MpkB that controls coordination of development and secondary metabolism; mutant has a moderate growth defect and arrested sexual development"
GBC12729.1g16447.t1RIR_0157100hypothetical protein-OG0000422--------
GBC12730.1g16448.t1RIR_0157200sequence orphan-OG0005086--------
GBC12731.1g16449.t2RIR_0157300vacuolar acidification-related protein-OG0001491YJR033C28.13.00E-87"Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate"AN070331.370Ortholog(s) have protein-containing complex binding activity
GBC12732.1g16449.t1RIR_0157300vacuolar acidification-related protein-OG0001491YJR033C27.493.00E-87"Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate"AN070331.150Ortholog(s) have protein-containing complex binding activity
GBC12733.1g16450.t1RIR_0157400DNA polymerase alpha catalytic subunit-OG0001900YNL102W36.490Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesisAN1075541.060"Ortholog(s) have DNA replication origin binding, DNA-directed DNA polymerase activity, chromatin binding, single-stranded DNA binding activity"
GBC12734.1g16451.t1RIR_0157500Pheromone processing carboxypeptidase Kex1-OG0000230YGL203C38.142.00E-91Cell death protease essential for hypochlorite-induced apoptosis; involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteinsAN1018439.672.00E-136Protein predicted to have a role in pheromone precursor processing
GBC12735.1g16452.t2RIR_0157600expressed protein-OG0004641--------
GBC12736.1g16452.t1RIR_0157600expressed protein-OG0004641--------
GBC12737.1g16453.t1RIR_0157700RNA exonuclease-OG0000541YGR276C31.672.00E-623'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcriptsAN756630.162.00E-73Has domain(s) with predicted exonuclease activity and intracellular localization
GBC12738.1g16454.t1RIR_0157800molybdate-anion transporter-like-OG0003915--------
GBC12739.1g16455.t1RIR_0157900protein kinase pak/ste20 kinase;kic1p-OG0000087YHR102W49.357.00E-98"Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"AN567440.72.00E-87"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC12740.1g16456.t1RIR_0158000hypothetical protein----------
GBC12741.1g16457.t1RIR_0158100putative membrane permease-OG0004313--------
GBC12742.1g16458.t1RIR_0158200hypothetical protein-OG0005001--------
GBC12743.1g16459.t1RIR_0158300Zinc-regulated transporter 1-OG0000344YGL255W39.072.00E-68High-affinity zinc transporter of the plasma membrane; responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factorAN379940.241.00E-74"Ortholog(s) have low-affinity zinc ion transmembrane transporter activity, role in response to zinc ion, zinc ion import across plasma membrane and plasma membrane localization"
GBC12744.1g16460.t1RIR_0158400hypothetical protein-OG0000797--------
GBC12745.1g16461.t1RIR_0158500zinc metalloprotease-OG0001436----AN803125.792.00E-16"Ortholog of A. fumigatus Af293 : Afu5g02250, A. niger CBS 513.88 : An02g10580, A. oryzae RIB40 : AO090102000288, Aspergillus wentii : Aspwe1_0042830 and Aspergillus sydowii : Aspsy1_0156829"
GBC12746.1g16462.t1RIR_0158600leucine-rich repeat protein sog2-OG0000013YOR353C28.492.00E-11Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosisAN443532.482.00E-24"Ortholog(s) have role in positive regulation of establishment of bipolar cell polarity regulating cell shape and cell division site, cytoplasm, mitotic spindle pole body localization"
GBC12747.1Tis13_98144RIR_0158610Tis13_98144----------
GBC12748.1g16463.t1RIR_0158700Anthranilate synthase component-OG0003962YER090W54.990"Anthranilate synthase; catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p"AN369557.090Putative anthranilate synthase with a predicted role in aromatic amino acid biosynthesis
GBC12749.1g16464.t1RIR_015880040S ribosomal protein S11-OG0001442YDR025W66.882.00E-72"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S11 and bacterial S17; N-terminally propionylated in vivo; RPS11A has a paralog, RPS11B, that arose from the whole genome duplication"AN522271.072.00E-74"Ortholog(s) have structural constituent of ribosome activity and role in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal small subunit assembly"
GBC12750.1g16465.t1RIR_0158900c3hc zinc finger protein-OG0003902--------
GBC12751.1g16466.t1RIR_0159000get complex subunit get1-OG0002827----AN434240.917.00E-28"Ortholog of A. fumigatus Af293 : Afu4g06340, A. niger CBS 513.88 : An04g00670, A. oryzae RIB40 : AO090023000956, Aspergillus wentii : Aspwe1_0101176 and Aspergillus sydowii : Aspsy1_0036624"
GBC12752.1g16467.t1RIR_0159100pre-rRNA-processing protein ipi1-OG0003041YHR085W31.784.00E-19Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential geneAN866832.321.00E-16Ortholog(s) have chromatin binding activity
GBC12753.1g16467.t2RIR_0159100pre-rRNA-processing protein ipi1-OG0003041YHR085W33.175.00E-19Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential geneAN866832.323.00E-18Ortholog(s) have chromatin binding activity
GBC12754.1g16468.t1RIR_0159200Transcription elongation factor S-II-OG0001292YGL043W30.177.00E-42General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stressAN486132.547.00E-51"Ortholog(s) have RNA polymerase II core binding, RNA polymerase II regulatory region DNA binding, transcription factor activity, core RNA polymerase II recruiting activity"
GBC12755.1g16469.t1RIR_0159300Mitochondrial 54S ribosomal protein YmL35-OG0000357YDR322W32.474.00E-32Mitochondrial ribosomal protein of the large subunitAN684232.877.00E-44Putative ortholog of S. cerevisiae Mrpl35p which is a mitochondrial large ribosomal subunit; expression reduced after exposure to farnesol
GBC12756.1g16470.t1RIR_0159400pi31 proteasome regulator-OG0002619--------
GBC12757.1g16471.t1RIR_0159500hypothetical protein-OG0006195--------
GBC12759.1g16473.t1RIR_0159700RNA-directed DNA polymerase from mobile element-OG0000001----AN036827.057.00E-12"Has domain(s) with predicted RNA binding, RNA-DNA hybrid ribonuclease activity, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in RNA-dependent DNA biosynthetic process"
GBC12760.1g16474.t1RIR_0159800hypothetical protein----------
GBC12761.1g16475.t1RIR_0159900hypothetical protein----------
GBC12762.1g16476.t1RIR_0160000F-box domain-containing protein-OG0003441YLR097C32.963.00E-23"Putative SCF-ubiquitin ligase F-box protein; based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies"AN6086289.00E-19"Putative F-box protein; ortholog(s) have role in SCF-dependent proteasomal ubiquitin-dependent protein catabolism, cellular response to methylmercury and SCF ubiquitin ligase complex localization; NeddH-associated protein"
GBC12763.1g16477.t1RIR_0160100scf ubiquitin ligase complex subunit hrt3----------
GBC12764.1g16478.t1RIR_0160200CBF1/Su(H)/LAG-1 family transcription factor-OG0000590--------
GBC12765.1g16479.t1RIR_0160300Putative RNA-processing beta-lactamase-fold-OG0004078YLR277C34.081.00E-84"Putative endoribonuclease; subunit of the mRNA cleavage and polyadenylation specificity complex; required for 3' processing, splicing, and transcriptional termination of mRNAs and snoRNAs; protein abundance increases in response to DNA replication stress; YSH1 has a paralog, SYC1, that arose from the whole genome duplication"AN099032.597.00E-75Ortholog(s) have mRNA cleavage and polyadenylation specificity factor complex localization
GBC12766.1g16480.t1RIR_0160400Proteasome subunit alpha type-5-OG0000088YGR253C69.968.00E-122Alpha 5 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit zetaAN587272.735.00E-133"Ortholog(s) have role in proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process"
GBC12767.1g16481.t1RIR_0160500Exocyst complex component EXO84-OG0002997YBR102C23.784.00E-42Exocyst subunit with dual roles in exocytosis and spliceosome assembly; subunit of the the exocyst complex which mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane (PM) prior to SNARE-mediated fusion; required for exocyst assembly and targeting the complex to specific sites on the bud tip PM; associates the U1 snRNP; role in pre-mRNA splicing and prespliceosome formation; possible Cdc28 substrateAN056034.934.00E-37"Ortholog(s) have role in Golgi to plasma membrane transport, exocyst assembly, exocyst localization, spliceosomal complex assembly and cellular bud neck, cellular bud tip, exocyst, incipient cellular bud site localization"
GBC12768.1g16482.t1RIR_0160600Synaptobrevin/VAMP-like protein-OG0001887YKL196C50.256.00E-71"Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus"AN848846.465.00E-57"Ortholog(s) have SNAP receptor activity, palmitoyltransferase activity"
GBC12769.1g16483.t1RIR_0160700TBC1 domain family member 5-OG0002916----AN453737.933.00E-64Has domain(s) with predicted intracellular localization
GBC12770.1g16484.t2RIR_0160800Vacuolar fusion protein MON1-OG0002536YGL124C37.277.00E-58"Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate"AN209338.926.00E-92"Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-5-phosphate binding, phosphatidylserine binding activity"
GBC12771.1g16484.t1RIR_0160800Vacuolar fusion protein MON1-OG0002536YGL124C36.715.00E-58"Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate"AN209338.924.00E-92"Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-5-phosphate binding, phosphatidylserine binding activity"
GBC12772.1g16485.t1RIR_0160900"zinc finger, c2h2 domain-containing protein"----------
GBC12773.1g16485.t2RIR_0160900"zinc finger, c2h2 domain-containing protein"----------
GBC12774.1g16486.t1RIR_0161000hypothetical protein----------
GBC12775.1g16487.t1RIR_0161100sterol binding ankyrin repeat protein-OG0000471YDL019C38.427.00E-74"Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH2 has a paralog, SWH1, that arose from the whole genome duplication"AN342443.494.00E-88Has domain(s) with predicted phospholipid binding activity
GBC12776.1g16488.t1RIR_0161200hypothetical protein-OG0001752----AN210122.432.00E-15"Protein involved in karyogamy, required for spindle and microtubule positioning; ortholog of S. cerevisiae KAR9"
GBC12777.1g16489.t1RIR_0161300DNA-directed RNA polymerase II subunit RPB2-OG0001605YOR151C61.60RNA polymerase II second largest subunit B150; part of central core; similar to bacterial beta subunitAN912060.460"Ortholog(s) have DNA binding, DNA-directed 5'-3' RNA polymerase activity, RNA binding activity and role in chromatin silencing by small RNA, transcription by RNA polymerase II"
GBC12778.1JEMT01016776.1_cds_EXX69836.1_10191RIR_0161310JEMT01016776.1_cds_EXX69836.1_10191-OG0003816----AN1231947.464.00E-12Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization
GBC12779.1g16490.t1RIR_0161400ADP-ribosylation factor-like protein-OG0005147--------
GBC12780.1Tis13_343878RIR_0161410Tis13_343878----------
GBC12781.1g16491.t1RIR_0161500Adenylosuccinate lyase-OG0002580YLR359W68.660Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiencyAN620965.280Putative 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase with a predicted role in purine metabolism; adenylosuccinate lyase; expression reduced after exposure to farnesol
GBC12782.1g16492.t1RIR_0161600chaperone protein dnaj-OG0003846YMR214W44.128.00E-12One of several homologs of bacterial chaperone DnaJ; located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteinsAN910133.121.00E-42"Ortholog of A. fumigatus Af293 : Afu7g02090, A. niger CBS 513.88 : An12g00580, A. oryzae RIB40 : AO090038000586, Aspergillus wentii : Aspwe1_0158097 and Aspergillus sydowii : Aspsy1_0061410"
GBC12783.1g16493.t1RIR_0161700nucleus protein-OG0000033YIR023W22.114.00E-15Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolismAN140654.96.00E-50"Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated"
GBC12784.1g16494.t1RIR_0161800transcription factor e2f6-OG0000008--------
GBC12785.1g16495.t3RIR_0161900hypothetical protein-OG0000069--------
GBC12786.1g16495.t1RIR_0161900hypothetical protein-OG0000069--------
GBC12787.1g16495.t2RIR_0161900hypothetical protein-OG0000069--------
GBC12788.1Tis13_338516RIR_0161910Tis13_338516----------
GBC12791.1g16497.t1RIR_0162100hypothetical protein-OG0000052--------
GBC12792.1g16498.t1RIR_0162200retrotransposable element-OG0000004YIL082W-A41.43.00E-101"Chr IX from 205635-206485,206487-210132, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN547041.161.00E-97Predicted gypsy transposon-related ORF
GBC12793.1g16499.t1RIR_0162300retrotransposable element-OG0000004YGR109W-B28.682.00E-38"Chr VII from 707610-708459,708461-712254, Genome Release 64-2-1, transposable_element_gene, ""Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes"AN1064927.712.00E-31"Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity, nucleic acid binding activity and role in DNA integration, RNA-dependent DNA biosynthetic process"
GBC12794.1g16500.t1RIR_0162400zinc finger domain-containing protein-OG0001079YLR136C33.336.00E-19"mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication"----
GBC12795.1g16501.t1RIR_0162500"Serine/threonine protein phosphatase 2A,"-OG0000251YDL188C75.570"Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; PPH22 has a paralog, PPH21, that arose from the whole genome duplication"AN6391910Protein phosphatase
GBC12796.1g16502.t1RIR_0162600protein far1-related sequence 11-like----------
GBC12797.1g16503.t1RIR_0162700CENP-b protein 1-OG0000010----AN615634.297.00E-41"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC12798.1g16504.t1RIR_0162800Low molecular weight phosphotyrosine protein-OG0002148YPR073C52.631.00E-53Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenineAN1057037.827.00E-36Putative protein tyrosine phosphatase; reduced growth on AVICEL medium and reduced eglA and eglB expression
GBC12799.1g16505.t1RIR_0162900conserved fungal protein-OG0003514YDR514C29.915.00E-17"Protein of unknown function that localizes to mitochondria; overexpression affects endocytic protein trafficking; YDR514C has a paralog, GFD2, that arose from the whole genome duplication"----
GBC12800.1g16506.t3RIR_0163000"protein prenyltransferase, putative"-OG0000438----AN0927363.00E-60"Ortholog(s) have NEDD8-specific protease activity, thiol-dependent ubiquitin-specific protease activity and role in cellular response to drug, cytoplasm protein quality control by the ubiquitin-proteasome system, protein deneddylation"
GBC12801.1g16506.t2RIR_0163000"protein prenyltransferase, putative"-OG0000438----AN0927362.00E-63"Ortholog(s) have NEDD8-specific protease activity, thiol-dependent ubiquitin-specific protease activity and role in cellular response to drug, cytoplasm protein quality control by the ubiquitin-proteasome system, protein deneddylation"
GBC12802.1g16506.t1RIR_0163000"protein prenyltransferase, putative"-OG0000438----AN0927361.00E-63"Ortholog(s) have NEDD8-specific protease activity, thiol-dependent ubiquitin-specific protease activity and role in cellular response to drug, cytoplasm protein quality control by the ubiquitin-proteasome system, protein deneddylation"
GBC12803.1g16506.t4RIR_0163000"protein prenyltransferase, putative"-OG0000438--------
GBC12804.1g16507.t2RIR_0163100Pre-mRNA splicing factor-OG0002424----AN476039.153.00E-35Ortholog(s) have U2 snRNP localization
GBC12805.1g16507.t1RIR_0163100Pre-mRNA splicing factor-OG0002424----AN476035.72.00E-78Ortholog(s) have U2 snRNP localization
GBC12806.1g16508.t1RIR_0163200Pre-mRNA-splicing factor ATP-dependent RNA-OG0000142YGL120C73.082.00E-135"RNA helicase in the DEAH-box family; functions in both RNA polymerase I and polymerase II transcript metabolism; catalyzes removal of U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleoprotein complex; required for efficient biogenesis of both small- and large-subunit rRNAs; acts with Sqs1p to promote 20S to 18S rRNA processing catalyzed by endonuclease Nob1p"AN013363.36.00E-143Putative mRNA splicing factor ATP-dependent RNA helicase; ortholog of S. cerevisiae Prp43p; expression reduced after exposure to farnesol
GBC12807.1g16509.t1RIR_0163300Pre-mRNA-splicing factor ATP-dependent RNA-OG0000142YGL120C55.144.00E-111"RNA helicase in the DEAH-box family; functions in both RNA polymerase I and polymerase II transcript metabolism; catalyzes removal of U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleoprotein complex; required for efficient biogenesis of both small- and large-subunit rRNAs; acts with Sqs1p to promote 20S to 18S rRNA processing catalyzed by endonuclease Nob1p"AN013356.164.00E-116Putative mRNA splicing factor ATP-dependent RNA helicase; ortholog of S. cerevisiae Prp43p; expression reduced after exposure to farnesol
GBC12808.1g16510.t1RIR_0163400"Eukaryotic translation initiation factor 2B,"-OG0002676YLR291C36.431.00E-64Beta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expressionAN134440.431.00E-85"Ortholog(s) have enzyme regulator activity, guanyl-nucleotide exchange factor activity, translation initiation factor activity and role in cytoplasmic translational initiation, regulation of translational initiation"
GBC12809.1g16511.t1RIR_0163500kxdl motif-containing protein 1 isoform x1-OG0004804--------
GBC12810.1g16512.t1RIR_0163600lysophosphatidic acid acyltransferase loa1-OG0003905----AN634528.571.00E-16"Ortholog(s) have lysophosphatidic acid acyltransferase activity, role in cellular triglyceride homeostasis, lipid particle organization and endoplasmic reticulum, lipid droplet localization"
GBC12811.1g16513.t1RIR_0163700cell growth-regulating nucleolar protein-OG0003661YCR087C-A59.386.00E-20Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential geneAN376052.381.00E-18"Ortholog of A. fumigatus Af293 : Afu7g04700, A. niger CBS 513.88 : An13g01230, A. oryzae RIB40 : AO090005000164, Aspergillus wentii : Aspwe1_0170408 and Aspergillus sydowii : Aspsy1_0148937"
GBC12812.1g16514.t1RIR_0163800duf803 domain protein-OG0000584----AN867536.466.00E-61"ORF that was absent from the original release of version 4 of the A. nidulans annotation, but present in a previous version; reinstated into version 4 in AspGD as of July 2009"
GBC12813.1g16515.t1RIR_0163900hypothetical protein-OG0005431--------
GBC12814.1g16516.t1RIR_0164000ribonuclease----------
GBC12815.1g16517.t1RIR_0164100f-box only protein 11-like-OG0005833--------
GBC12816.1g16517.t3RIR_0164100f-box only protein 11-like-OG0005833--------
GBC12817.1g16517.t2RIR_0164100f-box only protein 11-like-OG0005833--------
GBC12819.1g16519.t1RIR_0164300RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC12820.1g16520.t1RIR_0164400CENP-b protein 1-OG0000010YDR081C27.852.00E-18Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditionsAN871737.243.00E-48"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC12821.1g16521.t1RIR_0164500hypothetical protein----------
GBC12823.1g16522.t1RIR_0164600hypothetical protein-OG0008290----AN492823.115.00E-11"Ortholog(s) have RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly activity"
GBC12824.1g16523.t1RIR_0164700"N-alpha-acetyltransferase 30, NatC catalytic"-OG0002802YPR051W51.614.00E-44Catalytic subunit of the NatC type N-terminal acetyltransferase; involved in subcellular targeting of select N-terminally acetylated substrates to the Golgi apparatus (Arl3p and Grh1p) and the inner nuclear membrane (Trm1p); required for replication of dsRNA virusAN499350.314.00E-50Putative GNAT-type acetyltransferase
GBC12825.1g16524.t1RIR_0164800-D-dependent deacetylase sirtuin 5-OG0005437YOL068C25.782.00E-16"NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication"AN178236.121.00E-53Has domain(s) with predicted NAD+ binding activity
GBC12826.1g16525.t1RIR_0164900U2 small nuclear ribonucleoprotein B'-OG0000843YIR009W40.487.00E-17"U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members"AN010934.333.00E-40Ortholog(s) have U1 snRNP localization
GBC12827.1g16526.t1RIR_0165000hypothetical protein----------
GBC12828.1g16526.t2RIR_0165000hypothetical protein----------
GBC12833.1g16530.t1RIR_0165400transposable element tc3 transposase-OG0000005----AN1006627.031.00E-23Predicted mariner transposon-related ORF
GBC12834.1g16531.t1RIR_0165500zinc-ribbon domain-containing protein----------
GBC12835.1g16532.t1RIR_0165600Dolichyl-diphosphooligosaccharide-protein-OG0001459----AN742636.893.00E-64"Ortholog(s) have dolichyl-diphosphooligosaccharide-protein glycotransferase activity and role in cellular protein-containing complex assembly, protein N-linked glycosylation, protein O-linked mannosylation"
GBC12836.1g16533.t1RIR_0165700hypothetical protein----------
GBC12837.1g16534.t1RIR_0165800SNARE Slt1 (predicted)-OG0003086--------
GBC12838.1g16535.t1RIR_0165900zinc finger bed domain-containing protein-OG0000008----AN11074243.00E-12Predicted hAT transposon-related ORF
GBC12839.1g16536.t1RIR_0166000Mitochondrial 37S ribosomal protein MRP2-OG0003638YPR166C43.884.00E-27Mitochondrial ribosomal protein of the small subunitAN461148.964.00E-24Ortholog(s) have structural constituent of ribosome activity
GBC12840.1g16537.t1RIR_0166100"Alpha-1,4 glucan phosphorylase"GT35OG0001996YPR160W57.310Glycogen phosphorylase required for the mobilization of glycogen; non-essential; regulated by cyclic AMP-mediated phosphorylation; expression is regulated by stress-response elements and by the HOG MAP kinase pathwayAN101561.160Putative phosphorylase with a predicted role in glycogen degradation
GBC12841.1g16538.t1RIR_0166200zinc finger bed domain-containing protein-OG0000008--------
GBC12842.1g16539.t1RIR_0166300zinc finger bed domain-containing protein-OG0000008----AN1107432.322.00E-17Predicted hAT transposon-related ORF
GBC12844.1g16540.t1RIR_0166400RNA-directed DNA polymerase from mobile element-OG0000383--------
GBC12847.1g16543.t1RIR_0166700RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC12848.1g16544.t1RIR_0166800hypothetical protein----------
GBC12851.1g16547.t1RIR_0167100hypothetical protein-OG0000034--------
GBC12853.1g16549.t1RIR_0167300zinc finger bed domain-containing protein-OG0000008----AN1107431.371.00E-16Predicted hAT transposon-related ORF
GBC12854.1g16550.t1RIR_0167400zinc finger bed domain-containing protein-OG0000008--------
GBC12856.1g16552.t1RIR_0167600hypothetical protein-OG0000026--------
GBC12857.1g16553.t1RIR_0167700hypothetical protein-OG0000026--------
GBC12859.1g16555.t1RIR_01679005'-AMP-activated protein kinase subunit beta-1CBM20OG0001003--------
GBC12860.1g16556.t1RIR_0168000Biogenesis of lysosome-related organellescomplex-OG0004726--------
GBC12861.1g16557.t1RIR_0168100Cystathionine beta-synthase-OG0001033YGR155W34.062.00E-89"Cystathionine beta-synthase; catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog CBS cause homocystinuria"AN582035.668.00E-94"Cystathionine beta-synthase, an enzyme involved in methionine, S-adenosylmethionine, and cysteine biosynthesis; intracellular, menadione stress-induced protein"
GBC12862.1g16558.t1RIR_0168200hypothetical protein-OG0004590--------
GBC12863.1g16559.t1RIR_0168300Translation elongation factor EF-1 alpha-OG0000253YPR080W86.490"Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes; may also have a role in tRNA re-export from the nucleus; TEF1 has a paralog, TEF2, that arose from the whole genome duplication"AN421886.910"Ortholog(s) have GDP binding, GTP binding, Rho GTPase binding, actin filament binding, calmodulin binding, translation elongation factor activity"
GBC12864.1g16560.t1RIR_0168400mitochondrial peptidyl-tRNA hydrolase pth1-OG0001596YHR189W29.473.00E-15"One of two mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for respiratory growth on rich medium, but required for respiratory growth on minimal medium; see also PTH2"----
GBC12865.1g16560.t2RIR_0168400mitochondrial peptidyl-tRNA hydrolase pth1-OG0001596--------
GBC12866.1g16561.t1RIR_0168500hypothetical protein----------
GBC12867.1g16562.t1RIR_0168600Phosphoprotein phosphatase CDC14-OG0000671--------
GBC12868.1g16563.t1RIR_0168700-DH dehydrogenase-OG0004739--------
GBC12869.1g16564.t1RIR_0168800Ribosomal 60S subunit protein L32-OG0001355YBL092W63.033.00E-49"Ribosomal 60S subunit protein L32; overexpression disrupts telomeric silencing; homologous to mammalian ribosomal protein L32, no bacterial homolog"AN735464.624.00E-56"Ortholog(s) have structural constituent of ribosome activity, role in translation and cytosolic large ribosomal subunit localization"
GBC12870.1g16565.t1RIR_0168900dcp1-like decapping protein-OG0001638----AN774627.644.00E-12Putative mRNA decapping enzyme
GBC12871.1g16565.t2RIR_0168900dcp1-like decapping protein-OG0001638--------
GBC12872.1g16566.t1RIR_0169000ankyrin repeat protein-OG0000017----AN876735.881.00E-13"Ortholog of A. fumigatus Af293 : Afu3g02830, Afu8g02140, A. niger CBS 513.88 : An10g00890, An04g07720, An02g09440 and A. oryzae RIB40 : AO090011000172, AO090023000667"
GBC12873.1g16567.t1RIR_0169100DnaJ homolog subfamily B member 6-OG0000067YNL064C53.952.00E-18Type I HSP40 co-chaperone; involved in regulation of HSP90 and HSP70 functions; critical for determining cell size at Start as a function of growth rate; involved in protein translocation across membranes; member of the DnaJ familyAN223853.953.00E-18Has domain(s) with predicted unfolded protein binding activity and role in protein folding
GBC12874.1g16568.t1RIR_0169200Serine/threonine protein kinase-OG0000023YAL017W48.772.00E-78"PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication"AN453637.736.00E-113Ortholog(s) have protein serine/threonine kinase activity
GBC12875.1g16569.t1RIR_0169300specific transcriptional repressor-OG0000165--------
GBC12877.1g16570.t1RIR_0169400hypothetical protein-OG0004139--------
GBC12879.1g16572.t1RIR_0169600zinc finger bed domain-containing protein-OG0000008--------
GBC12880.1g16573.t1RIR_0169700zinc finger bed domain-containing protein----------
GBC12882.1g16575.t1RIR_0169900cyclin-dependent protein kinase regulator pho80-OG0000378YOL001W35.595.00E-31"Cyclin; interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling"AN515644.383.00E-42"Pho80-like cyclin involved in regulation of development and phosphate homeostasis, interacts with the cyclin-dependent kinase PhoA"
GBC12883.1g16576.t1RIR_0170000stomatin-like protein 2-OG0003674----AN128760.331.00E-120"Putative stomatin-like protein, localizes in mitochondria"
GBC12884.1g16577.t1RIR_0170100lipid particle protein-OG0000698YOR059C29.965.00E-43Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stressAN308426.681.00E-52"Ortholog(s) have lysophospholipase activity, role in lipid homeostasis and lipid droplet localization"
GBC12885.1g16578.t1RIR_0170200hypothetical protein----------
GBC12886.1g16579.t1RIR_0170300Carboxypeptidase C-OG0000230YMR297W49.121.00E-150"Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family"AN544252.164.00E-150Putative carboxypeptidase Y
GBC12887.1g16580.t1RIR_0170400Mitogen-activated protein kinase kinase kinase--YFR014C28.492.00E-14"Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication"AN438527.175.00E-14"Serine/threonine protein kinase involved in septation; required for actin ring formation during cytokinesis; mutants have strong growth defect, septation and conidiation defects, sensitivity to NaCl"
GBC12888.1g16581.t1RIR_0170500set1c phd finger protein spf1-OG0000255YPL138C26.653.00E-12"Subunit of COMPASS (Set1C); a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein; relocalizes to the cytosol in response to hypoxia"AN285043.627.00E-18"Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity and role in histone H3-K4 methylation, regulation of secondary metabolite biosynthetic process"
GBC12889.1g16582.t1RIR_0170600Pre-mRNA-splicing factor ISY1-OG0003124YJR050W28.41.00E-20"Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs; interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles"AN470749.752.00E-58"Ortholog(s) have role in cellular response to drug and Prp19 complex, U2-type post-mRNA release spliceosomal complex localization"
GBC12890.1g16583.t1RIR_0170700myosin regulatory light chain cdc4-OG0000072YGL106W41.611.00E-28"Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition"AN204739.862.00E-30Calmodulin; EF-hands containing calcium binding protein; required for normal progression through the cell-cycle; localizes to hyphal tips and transiently to sites of septation; transcript upregulated in response to camptothecin
GBC12891.1g16584.t1RIR_0170800Exocyst complex subunit Exo70 (predicted)-OG0003021YJL085W24.88.00E-36"Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in an actin-independent manner, targeting and anchoring the exocyst with Sec3p; involved in exocyst assembly; direct downstream effector of Rho3p and Cdc42p; relocalizes from bud neck to cytoplasm upon DNA replication stress"AN621028.732.00E-70"Ortholog(s) have GTP-Rho binding, phosphatidylinositol-4,5-bisphosphate binding activity and role in Golgi to plasma membrane transport, Rho protein signal transduction, exocyst assembly, exocyst localization"
GBC12892.1g16585.t1RIR_0170900"Phosphatidylinositol glycan, class M"GT50OG0002748YJR013W42.32.00E-68"Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M"AN337043.661.00E-84"Ortholog(s) have mannosyltransferase activity, role in GPI anchor biosynthetic process, fungal-type cell wall organization, hyphal growth and glycosylphosphatidylinositol-mannosyltransferase I complex localization"
GBC12893.1g16586.t1RIR_0171000Ribosomal 60S subunit protein L13-OG0001117YDL082W49.721.00E-47"Ribosomal 60S subunit protein L13A; not essential for viability; homologous to mammalian ribosomal protein L13, no bacterial homolog; RPL13A has a paralog, RPL13B, that arose from the whole genome duplication"AN700352.238.00E-62"Ortholog(s) have cell surface, cytosolic large ribosomal subunit localization"
GBC12894.1g16587.t1RIR_0171100-DPH cytochrome p450 reductase-OG0000656YPR048W32.674.00E-90Conserved NAPDH-dependent diflavin reductase; component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; transfers electrons from NADPH to the Fe-S cluster of Dre2p; plays a pro-death role under oxidative stress; Tah18p-dependent nitric oxide synthesis confers high-temperature stress tolerance; possible target for development of antifungal drugsAN364274.063.00E-157"Ortholog(s) have role in cellular response to starvation and filamentous growth of a population of unicellular organisms in response to biotic stimulus, more"
GBC12895.1g16588.t1RIR_0171200Transcription initiation factor TFIIB subunit-OG0001586YPR086W39.861.00E-56Transcription factor TFIIB; a general transcription factor required for transcription initiation and start site selection by RNA polymerase IIAN492845.171.00E-78"Ortholog(s) have RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly activity"
GBC12896.1Tis13_67239RIR_0171210Tis13_67239-OG0001361YOR182C75.441.00E-18"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S30, no bacterial homolog; RPS30B has a paralog, RPS30A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress"AN870576.272.00E-22Ortholog(s) have cytoplasmic stress granule localization
GBC12897.1g16589.t1RIR_0171300par a family ATPase/wd repeat iron cluster-OG0000051YDR267C41.381.00E-76"Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia2p and Met18p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; contains WD40 repeats; ortholog of human Ciao1 protein"AN138534.281.00E-59"Ortholog(s) have role in iron-sulfur cluster assembly, tRNA wobble uridine modification and cytosol, nucleus localization"
GBC12898.1g16590.t1RIR_0171400Tyrosine phosphatase protein-OG0000397YNL099C44.972.00E-47Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNAAN442637.52.00E-30"Ortholog(s) have role in actin filament organization, endocytosis"
GBC12899.1g16591.t1RIR_0171500RNA binding protein-OG0001936YGR159C27.577.00E-11Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis----
GBC12900.1JEMT01029722.1_cds_EXX51105.1_28925RIR_0171510JEMT01029722.1_cds_EXX51105.1_28925-OG0004389----AN1184338.144.00E-16"Ortholog of A. fumigatus Af293 : Afu1g11535, Aspergillus wentii : Aspwe1_0040556, Aspergillus sydowii : Aspsy1_0083601 and Aspergillus carbonarius ITEM 5010 : Acar5010_202812"
GBC12901.1g16592.t1RIR_0171600RNA polymerase III transcription factor IIIC-OG0002064YBR123C23.665.00E-19Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63AN799729.44.00E-49"Ortholog(s) have chromatin insulator sequence binding, transcription factor activity, core RNA polymerase III binding activity and role in transcription initiation from RNA polymerase III promoter"
GBC12902.1g16593.t1RIR_0171700Histone deacetylase complex protein Sin3-OG0000591YOL004W44.210"Component of both the Rpd3S and Rpd3L histone deacetylase complexes; involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity"AN154670.276.00E-143"Histone deacetylase complex, SIN3 component; this locus is reported to contain an upstream open reading frame (uORF)"
GBC12903.1g16594.t2RIR_0171800zinc finger protein 207-OG0002876--------
GBC12904.1g16594.t1RIR_0171800zinc finger protein 207-OG0002876--------
GBC12905.1g16595.t1RIR_0171900wd repeat-containing protein-OG0001091----AN1021636.442.00E-68"Ortholog of A. fumigatus Af293 : Afu8g05640, A. niger CBS 513.88 : An15g04470, A. oryzae RIB40 : AO090005000578, Aspergillus wentii : Aspwe1_0118846 and Aspergillus sydowii : Aspsy1_0055743"
GBC12908.1g16598.t1RIR_0172200hypothetical protein----------
GBC12911.1g16601.t1RIR_0172500hypothetical protein-OG0000026--------
GBC12912.1g16602.t1RIR_0172600DNA repair protein RAD5-OG0000193YLR032W35.492.00E-143"DNA helicase/Ubiquitin ligase; involved in error-free branch of DNA damage tolerance (DDT) pathway; proposed to promote replication fork regression during postreplication repair by template switching; stimulates synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; required for error-prone translesion synthesis; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells"AN004436.790"Ortholog(s) have ubiquitin protein ligase activity, role in nucleotide-excision repair, postreplication repair, protein ubiquitination and site of double-strand break localization"
GBC12913.1g16603.t2RIR_0172700hypothetical protein----------
GBC12914.1g16603.t1RIR_0172700hypothetical protein----------
GBC12915.1g16604.t2RIR_0172800hypothetical protein-OG0005377--------
GBC12916.1g16604.t3RIR_0172800hypothetical protein-OG0005377--------
GBC12917.1g16604.t1RIR_0172800hypothetical protein-OG0005377--------
GBC12918.1g16605.t1RIR_0172900TDG/mug DNA glycosylase family protein-OG0002491----AN547929.531.00E-18"Ortholog of A. fumigatus Af293 : Afu6g13340, A. niger CBS 513.88 : An08g10020, A. oryzae RIB40 : AO090003000458, Neosartorya fischeri NRRL 181 : NFIA_059260 and Aspergillus wentii : Aspwe1_0022439"
GBC12919.1g16606.t1RIR_0173000hypothetical protein-OG0006571--------
GBC12920.1g16607.t1RIR_0173100Glutamate dehydrogenase NAD(P)+----------
GBC12921.1g16608.t1RIR_0173200Putative mitochondrial 37S ribosomal protein-OG0002960YNR036C59.026.00E-45Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteinsAN473065.654.00E-51"Has domain(s) with predicted structural constituent of ribosome activity, role in translation and ribosome, small ribosomal subunit localization"
GBC12922.1g16609.t1RIR_0173300hypothetical protein----------
GBC12923.1g16610.t1RIR_0173400Periodic tryptophan protein 1-OG0002076YLR196W36.941.00E-92Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamilyAN031049.692.00E-154"Ortholog of A. fumigatus Af293 : Afu1g02630, A. niger CBS 513.88 : An01g05580, A. oryzae RIB40 : AO090005000833, Aspergillus wentii : Aspwe1_0151261 and Aspergillus sydowii : Aspsy1_0027871"
GBC12924.1g16611.t1RIR_0173500CP2 transcription factor-OG0000922----AN487832.437.00E-30Putative transcription factor of unknown function; expression upregulated after exposure to farnesol
GBC12925.1g16612.t1RIR_0173600UDP-glucose 6-dehydrogenase-OG0002095----AN917224.12.00E-38"Has domain(s) with predicted NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor activity and role in oxidation-reduction process"
GBC12926.1g16613.t2RIR_0173700tRNA-dihydrouridine synthase 2-OG0003148YNR015W36.624.00E-65"Dihydrouridine synthase; member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs"AN296738.815.00E-76"Has domain(s) with predicted catalytic activity, flavin adenine dinucleotide binding, tRNA dihydrouridine synthase activity and role in oxidation-reduction process, tRNA processing"
GBC12927.1g16613.t1RIR_0173700tRNA-dihydrouridine synthase 2-OG0003148YNR015W36.532.00E-63"Dihydrouridine synthase; member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs"AN296738.546.00E-73"Has domain(s) with predicted catalytic activity, flavin adenine dinucleotide binding, tRNA dihydrouridine synthase activity and role in oxidation-reduction process, tRNA processing"
GBC12928.1g16614.t1RIR_0173800survival factor 1-OG0002294YDR222W26.983.00E-21"Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YDR222W has a paralog, YLR225C, that arose from the whole genome duplication"AN011736.062.00E-67Ortholog(s) have role in cellular response to oxidative stress
GBC12929.1g16615.t1RIR_0173900hypothetical protein-OG0006589--------
GBC12930.1g16616.t1RIR_0174000Phosphoribosylglycinamide formyltransferase-OG0003864YDR408C42.181.00E-46Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathwayAN1075341.231.00E-51"Ortholog(s) have phosphoribosylglycinamide formyltransferase activity, role in 'de novo' IMP biosynthetic process, adenine biosynthetic process and biofilm matrix localization"
GBC12931.1g16617.t3RIR_0174100cop9 signalosome complex subunit 1-OG0003074YPR108W23.861.00E-13"Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits"AN149141.452.00E-102Subunit 1 of the COP9 signalosome; metalloprotease that binds zinc ions by its conserved JAMM motif; required for formation of cleistothecia; mutants produce aberrant red color within distinct hyphae; NeddH-associated protein
GBC12932.1g16617.t1RIR_0174100cop9 signalosome complex subunit 1-OG0003074YPR108W23.861.00E-13"Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits"AN149141.452.00E-102Subunit 1 of the COP9 signalosome; metalloprotease that binds zinc ions by its conserved JAMM motif; required for formation of cleistothecia; mutants produce aberrant red color within distinct hyphae; NeddH-associated protein
GBC12933.1g16617.t2RIR_0174100cop9 signalosome complex subunit 1-OG0003074YPR108W23.861.00E-13"Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits"AN149141.452.00E-102Subunit 1 of the COP9 signalosome; metalloprotease that binds zinc ions by its conserved JAMM motif; required for formation of cleistothecia; mutants produce aberrant red color within distinct hyphae; NeddH-associated protein
GBC12934.1g16618.t1RIR_0174200Ribonuclease H-OG0000332YMR234W32.513.00E-22Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I.AN518835.022.00E-44Ortholog(s) have nuclear chromatin localization
GBC12935.1g16619.t1RIR_0174300compass subunit protein swd1-OG0003011YAR003W31.22.00E-47Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7AN080831.724.00E-69Component of the Set1/COMPASS methytransferase complex; WD40 repeat protein; ortholog of S. cerevisiae Swd1p which has role in histone H3-K4 methylation; expression reduced after exposure to farnesol
GBC12936.1g16619.t3RIR_0174300compass subunit protein swd1-OG0003011YAR003W31.017.00E-50Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7AN080834.023.00E-80Component of the Set1/COMPASS methytransferase complex; WD40 repeat protein; ortholog of S. cerevisiae Swd1p which has role in histone H3-K4 methylation; expression reduced after exposure to farnesol
GBC12937.1g16619.t2RIR_0174300compass subunit protein swd1-OG0003011YAR003W30.41.00E-48Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7AN080831.493.00E-69Component of the Set1/COMPASS methytransferase complex; WD40 repeat protein; ortholog of S. cerevisiae Swd1p which has role in histone H3-K4 methylation; expression reduced after exposure to farnesol
GBC12938.1g16620.t1RIR_0174400aspergillopepsin-2 heavy chain-OG0000238----AN1052333.022.00E-29"Ortholog(s) have double-stranded DNA binding activity, role in double-strand break repair via homologous recombination and Smc5-Smc6 complex, nucleus localization"