home > Gene Annotation List

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NCBI IDProteinIDLocusTagProductIDCazyIDOrthGroupIDSGD IDidentevalAnnotationASpGD IDidentEvalAnnotation
GBC42400.1g16245.t2RIR_2561500hypothetical protein-OG0001561YPR095C42.962.00E-24"Guanine nucleotide exchange factor (GEF) for Arf proteins; promotes activation of Arl1p, which recruits Imh1p to the Golgi; involved in vesicular transport; member of the Sec7-domain family; contains a PH domain"AN612034.68.00E-91Predicted ADP ribosylation factor guanine nucleotide exchange factor (Arf GEF)
GBC42402.1g16247.t1RIR_2561700V-type ATPase V0 subunit A-OG0000706--------
GBC42403.1g16248.t1RIR_2561800Golgi to vacuole transport-related protein-OG0000362--------
GBC42404.1Tis13_5264RIR_2561810Tis13_5264--YOL113W30.067.00E-12"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN7737254.00E-11Ortholog(s) have protein serine/threonine kinase activity
GBC42405.1g16249.t1RIR_2561900CENP-b protein 1-OG0000010YAR019C26.775.00E-15Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN773730.944.00E-12Ortholog(s) have protein serine/threonine kinase activity
GBC42407.1g16250.t2RIR_2562000hypothetical protein----------
GBC42408.1g16250.t1RIR_2562000hypothetical protein----------
GBC42409.1g16251.t1RIR_2562100u4/u6 small nuclear ribonucleoprotein prp31-OG0002455--------
GBC42410.1g16251.t2RIR_2562100u4/u6 small nuclear ribonucleoprotein prp31-OG0002455--------
GBC42411.1g16252.t1RIR_2562200cut9 interacting protein scn1-OG0003768YKL166C26.182.00E-12"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN581523.991.00E-15Aurora protein serine/threonine kinase
GBC42412.1g16253.t1RIR_2562300Diphthine synthase-OG0002272--------
GBC42413.1g16254.t1RIR_2562400Dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolicholGT57OG0002794YKL166C25.666.00E-13"cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication"AN241228.988.00E-14Calcium/calmodulin-dependent protein kinase A; essential for growth and nuclear division; expression downregulated by farnesol; transcript upregulated by camptothecin; mutants have a moderate growth defect and increased pigment production
GBC42414.1g16255.t1RIR_2562500hypothetical protein----------
GBC42415.1g16255.t2RIR_2562500hypothetical protein--YLR362W28.572.00E-15"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress"AN581525.272.00E-17Aurora protein serine/threonine kinase
GBC42416.1g16256.t1RIR_2562600c2h2 transcription factor-OG0000003YKR094C57.536.00E-18"Ubiquitin-ribosomal 60S subunit protein L40B fusion protein; cleaved to yield ubiquitin and ribosomal protein L40B; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40B has a paralog, RPL40A, that arose from the whole genome duplication"AN200058.99.00E-18"Polyubiquitin, contains four head to tail repeats of ubiqiutin; transcript upregulated in response to camptothecin"
GBC42417.1g16257.t1RIR_2562700ATP-dependent RNA helicase-OG0000259--------
GBC42418.1g16258.t1RIR_2562800SWR1-complex protein 4-OG0003496YFR014C26.571.00E-15"Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication"AN427926.577.00E-14Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea
GBC42419.1g16259.t1RIR_2562900Presenilin enhancer 2-OG0004809--------
GBC42420.1g16260.t1RIR_25630006-pyruvoyltetrahydropterin/6--OG0004459YOR231W27.015.00E-11"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"----
GBC42421.1g16260.t3RIR_25630006-pyruvoyltetrahydropterin/6--OG0004459YDL101C27.737.00E-14"Cell-cycle checkpoint serine-threonine kinase; required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; Mec1p and Dun1p function in same pathway to regulate both dNTP pools and telomere length; also regulates postreplicative DNA repair"AN581526.844.00E-16Aurora protein serine/threonine kinase
GBC42422.1g16260.t2RIR_25630006-pyruvoyltetrahydropterin/6--OG0004459--------
GBC42423.1g16261.t2RIR_2563100hypothetical protein-OG0001084--------
GBC42424.1g16261.t1RIR_2563100hypothetical protein-OG0001084--------
GBC42425.1JEMT01017024.1_cds_EXX69022.1_11002RIR_2563110JEMT01017024.1_cds_EXX69022.1_11002-OG0004769--------
GBC42426.1g16262.t1RIR_2563200COP9 signalosome complex subunit 6-OG0003178--------
GBC42427.1g16263.t1RIR_2563300RAD50-like DNA repair protein-OG0001656YCL024W30.346.00E-14"Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication"AN427929.914.00E-16Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea
GBC42428.1g16264.t1RIR_2563400Ribosomal 60S subunit protein L24-OG0001111--------
GBC42429.1g16265.t1RIR_2563500hypothetical protein-OG0001198--------
GBC42431.1JEMT01025006.1_cds_EXX61821.1_18212RIR_2563610JEMT01025006.1_cds_EXX61821.1_18212-OG0006809YCR073C23.514.00E-13"MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication"AN1015325.452.00E-15Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC42434.1JEMT01025006.1_cds_EXX61819.1_18210RIR_2563810JEMT01025006.1_cds_EXX61819.1_18210--YOL113W24.42.00E-14"Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication"AN1015324.731.00E-15Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC42437.1g16271.t2RIR_2564100hypothetical protein-OG0004650--------
GBC42438.1g16271.t1RIR_2564100hypothetical protein-OG0004650--------
GBC42439.1g16272.t2RIR_2564200hypothetical protein----------
GBC42440.1g16272.t1RIR_2564200hypothetical protein----------
GBC42441.1g16273.t1RIR_2564300Ran GDP/GTP exchange factor-OG0000657--------
GBC42442.1g16274.t1RIR_2564400Rad1-like DNA repair protein-OG0001663YHL007C25.685.00E-14"Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family"AN1015325.874.00E-17Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC42443.1g16275.t1RIR_2564500hypothetical proteinCBM40---------
GBC42444.1Tis13_28535RIR_2564510Tis13_28535------AN1012730.248.00E-35Putative beta-glucosidase with a predicted role in polysaccharide degradation; predicted mariner transposon-related ORF
GBC42445.1g16276.t1RIR_2564600hypothetical protein----------
GBC42446.1g16277.t1RIR_2564700hypothetical protein----------
GBC42447.1g16278.t1RIR_2564800"SNAP receptor, synaptobrevin"-OG0000616YMR001C31.062.00E-12Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rholp guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate----
GBC42448.1g16279.t1RIR_2564900"nucleotide-binding, alpha-beta plait"-OG0002929--------
GBC42449.1g16280.t1RIR_2565000CENP-b protein 1-OG0000010--------
GBC42452.1g16283.t1RIR_2565300hypothetical protein-OG0000034--------
GBC42455.1g16286.t1RIR_2565600putative rve super family integrase-OG0000031--------
GBC42456.1g16287.t1RIR_2565700hypothetical protein----------
GBC42457.1g16288.t1RIR_2565800hypothetical protein--YCR079W35.414.00E-23Mitochondrial type 2C protein phosphatase (PP2C); has similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenaseAN091433.263.00E-63Putative serine/threonine phosphatase
GBC42462.1g16293.t1RIR_2566300putative protein-primed b-family DNA polymerase------AN738536.442.00E-69Putative phosphatidylserine decarboxylase with a predicted role in phospholipid metabolism
GBC42463.1g16294.t1RIR_2566400highly derived d5-like helicase-primase----------
GBC42466.1g16297.t1RIR_2566700"reverse transcriptase, partial"-OG0000001--------
GBC42467.1g16298.t1RIR_2566800hypothetical protein-OG0000929--------
GBC42468.1g16299.t1RIR_2566900AMP deaminase-OG0001313--------
GBC42470.1g16300.t1RIR_2567000Enhancer of mRNA-decapping protein 4-OG0004624--------
GBC42471.1g16301.t1RIR_2567100hypothetical protein----------
GBC42472.1g16302.t1RIR_2567200hypothetical protein-OG0000012--------
GBC42473.1g16303.t1RIR_2567300Complex I intermediate associated protein Cia30-OG0003545--------
GBC42474.1g16304.t1RIR_2567400Peroxisomal membrane protein pex16-OG0003049--------
GBC42475.1g16305.t1RIR_2567500phosphatidylserine decarboxylase-OG0000123--------
GBC42481.1g16310.t1RIR_2568000hypothetical protein-OG0000002--------
GBC42482.1JEMT01029830.1_cds_EXX50688.1_29343RIR_2568010JEMT01029830.1_cds_EXX50688.1_29343----------
GBC42485.1JEMT01029830.1_cds_EXX50686.1_29341RIR_2568210JEMT01029830.1_cds_EXX50686.1_29341------AN362224.672.00E-16Member of the RGS (regulator of G-protein signaling) family; expressed at constant level during the life cycle
GBC42487.1JEMT01029830.1_cds_EXX50684.1_29339RIR_2568310JEMT01029830.1_cds_EXX50684.1_29339-OG0000008--------
GBC42490.1g16315.t1RIR_2568500hypothetical protein-OG0002452--------
GBC42494.1g28801.t1RIR_2568900hypothetical protein-OG0000004YDR116C32.611.00E-26Mitochondrial ribosomal protein of the large subunitAN822523.899.00E-16Putative ribosomal protein L1; ortholog of S. cerevisiae Mrpl1p
GBC42496.1g28803.t1RIR_2569100gastrula zinc finger protein xlcgf46.1-OG0000287YFL039C57.612.00E-163"Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions"AN195369.950"Actin-related protein; dynactin complex subunit; physically associates with importin-alpha, KapA; required for proper vacuolar distribution in addition to normal nuclear distribution"
GBC42498.1g28805.t1RIR_2569300cytochrome p450 3a8-like isoform x2-OG0000007--------
GBC42500.1g3032.t1RIR_2569500cytochrome p450 family protein-OG0000007--------
GBC42502.1g3034.t1RIR_2569700serine/threonine protein kinase-OG0000000--------
GBC42503.1g3035.t1RIR_2569800sel1 repeat domain-containing protein-OG0000000YJL002C29.987.00E-52Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteinsAN747233.622.00E-75"Ortholog(s) have dolichyl-diphosphooligosaccharide-protein glycotransferase activity, role in protein N-linked glycosylation via asparagine and oligosaccharyltransferase complex, plasma membrane localization"
GBC42505.1g3037.t1RIR_2570000hypothetical protein-OG0006806YGR005C46.252.00E-18TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30AN153840.372.00E-15"Ortholog(s) have transcription factor activity, core RNA polymerase II binding activity and role in transcription elongation from RNA polymerase II promoter, transcriptional start site selection at RNA polymerase II promoter"
GBC42506.1g3038.t1RIR_2570100hypothetical protein------AN1006628.365.00E-26Predicted mariner transposon-related ORF
GBC42507.1g3039.t1RIR_2570200Elongator complex protein 2-OG0002599--------
GBC42508.1g3040.t1RIR_2570300arf guanyl-nucleotide exchange factor-OG0000181----AN871726.532.00E-24"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC42509.1Tis13_34076RIR_2570310Tis13_34076----------
GBC42510.1g3041.t1RIR_2570400serine/threonine protein kinase----------
GBC42512.1g3042.t1RIR_2570500protein kinase----------
GBC42513.1g3043.t1RIR_2570600serine-threonine protein kinase----------
GBC42514.1JEMT01023761.1_cds_EXX63818.1_16208RIR_2570610JEMT01023761.1_cds_EXX63818.1_16208--YKR089C40.943.00E-127"Multifunctional lipase/hydrolase/phospholipase; triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A2; catalyzes acyl-CoA dependent acylation of LPA to PA; required with Tgl3p for timely bud formation; phosphorylated and activated by Cdc28p; TGL4 has a paralog, TGL5, that arose from the whole genome duplication"AN171347.632.00E-154"Ortholog(s) have calcium-independent phospholipase A2 activity, lysophosphatidic acid acyltransferase activity, sterol esterase activity, triglyceride lipase activity"
GBC42516.1g3045.t1RIR_2570800hypothetical protein--YIR034C54.422.00E-142"Saccharopine dehydrogenase (NAD+, L-lysine-forming); catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway; also has mRNA binding activity"AN287356.168.00E-148"Putative saccharopine dehydrogenase (NAD+, L-lysine-forming) with a predicted role in lysine metabolism"
GBC42519.1g3048.t1RIR_2571100serine/threonine protein kinase--YJR025C49.694.00E-553-hydroxyanthranilic acid dioxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1pAN1125251.485.00E-58"Ortholog(s) have 3-hydroxyanthranilate 3,4-dioxygenase activity, role in 'de novo' NAD biosynthetic process from tryptophan and cytoplasm localization"
GBC42521.1g3049.t1RIR_2571200serine/threonine protein kinase----------
GBC42522.1g3050.t1RIR_2571300zinc finger mym-type protein 2-like--YML086C24.49.00E-12"D-Arabinono-1,4-lactone oxidase; catalyzes the final step in biosynthesis of dehydro-D-arabinono-1,4-lactone, which is protective against oxidative stress"AN083624.791.00E-11"Ortholog(s) have D-arabinono-1,4-lactone oxidase activity"
GBC42523.1g3051.t1RIR_2571400serine/threonine protein kinase----------
GBC42524.1g3052.t1RIR_2571500ubiquitin domain-containing protein----------
GBC42525.1g3053.t1RIR_2571600hypothetical protein-OG0000060--------
GBC42526.1g3054.t1RIR_2571700serine/threonine protein kinase--YER061C43.915.00E-113Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respirationAN748955.165.00E-170Putative type II fatty acid synthase with a predicted role in mitochondrial fatty acid formation; mitochondrial 3-oxoacyl-[acyl-carrier-protein]-synthase; putative polyketide synthase (PKS-like) protein
GBC42528.1g3055.t1RIR_2571800serine/threonine protein kinase--YER061C33.337.00E-14Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respirationAN748939.863.00E-23Putative type II fatty acid synthase with a predicted role in mitochondrial fatty acid formation; mitochondrial 3-oxoacyl-[acyl-carrier-protein]-synthase; putative polyketide synthase (PKS-like) protein
GBC42529.1g3056.t1RIR_2571900"protein kinase, putative"----------
GBC42530.1g3057.t1RIR_2572000"kelch-like protein 10, partial"-OG0000020YLR316C25.164.00E-19Subunit of tRNA-specific adenosine-34 deaminase; forms a heterodimer with Tad2p that converts adenosine to inosine at the wobble position of several tRNAs----
GBC42532.1JEMT01027444.1_cds_EXX57074.1_22955RIR_2572020JEMT01027444.1_cds_EXX57074.1_22955--YBR061C50.491.00E-98"2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; functionally complemented by human FTSJ1"AN175144.554.00E-76"Has domain(s) with predicted methyltransferase activity and role in RNA methylation, methylation"
GBC42534.1g3059.t1RIR_2572200hypothetical protein-OG0000024YML057W55.580"Calcineurin A; one isoform (the other is Cna1p) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1; regulates the function of Aly1p alpha-arrestin; CMP2 has a paralog, CNA1, that arose from the whole genome duplication"AN882073.930"Catalytic subunit of the calmodulin-dependent protein phosphatase (calcineurin A), required for cell cycle progression and for nucleocytoplasmic transport of CrzA in response to stress"
GBC42535.1g3060.t1RIR_2572300serine/threonine protein kinase--YGL212W23.539.00E-12Vacuolar SNARE protein; functions with Vam3p in vacuolar protein trafficking; has an N-terminal PX domain (phosphoinositide-binding module) that binds PtdIns-3-P and mediates membrane binding; SNAP-25 homolog; protein abundance increases in response to DNA replication stressAN1191328.972.00E-33"Ortholog(s) have role in Golgi to vacuole transport, vacuole fusion and fungal-type vacuole membrane, late endosome localization"
GBC42536.1g3061.t1RIR_2572400hypothetical protein--YIL046W24.012.00E-25"F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p"AN635930.13.00E-19Protein involved in sulfur metabolite repression; contains an F-box and seven WD repeats
GBC42537.1g3062.t1RIR_2572500hypothetical protein-OG0000036YIL046W27.212.00E-14"F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p"AN635930.13.00E-19Protein involved in sulfur metabolite repression; contains an F-box and seven WD repeats
GBC42538.1g3063.t1RIR_2572600hypothetical protein----------
GBC42539.1g3064.t1RIR_2572700serine/threonine protein kinase-OG0000000--------
GBC42542.1g3066.t1RIR_2572900serine/threonine protein kinase--YLR116W41.677.00E-97"Component of commitment complex; which defines first step in splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA; relocalizes to the cytosol in response to hypoxia"----
GBC42544.1g3068.t1RIR_2573100zinc finger bed domain-containing protein-OG0000008--------
GBC42548.1g3071.t1RIR_2573400hypothetical protein-OG0000024--------
GBC42550.1g3072.t1RIR_2573500hypothetical protein------AN1107427.942.00E-17Predicted hAT transposon-related ORF
GBC42551.1g3072.t2RIR_2573500hypothetical protein----------
GBC42552.1g3073.t1RIR_2573600transposable element tc3 transposase-OG0000005--------
GBC42553.1JEMT01020227.1_cds_EXX65896.1_14133RIR_2573610JEMT01020227.1_cds_EXX65896.1_14133-OG0000005--------
GBC42554.1g3074.t1RIR_2573700transposable element tc3 transposase-OG0000005--------
GBC42555.1g3075.t1RIR_2573800serine/threonine protein kinase----------
GBC42558.1g3077.t1RIR_2574000transposable element tc3 transposase-OG0000005--------
GBC42559.1g3078.t1RIR_2574100heat shock 70 kda protein 12b-like-OG0001936--------
GBC42560.1g3079.t1RIR_2574200hypothetical protein----------
GBC42561.1JEMT01029648.1_cds_EXX51549.1_28512RIR_2574210JEMT01029648.1_cds_EXX51549.1_28512----------
GBC42564.1Tis13_34820RIR_2574410Tis13_34820----------
GBC42565.1g3082.t1RIR_2574500Protein phosphatase PTC6-OG0002609--------
GBC42566.1g3083.t1RIR_2574600protein required for cell viability-OG0003682YLL041C73.315.00E-132"Iron-sulfur protein subunit of succinate dehydrogenase; the complex couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; other members are Sdh1p, Sdh3p, and Sdh4p"AN233268.22.00E-121Putative succinate dehydrogenase with a predicted role in the TCA cycle
GBC42567.1Tis13_10874RIR_2574610Tis13_10874--YFR021W53.041.00E-61"Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein; relocalizes from vacuole to cytoplasm upon DNA replication stress; has 4 mammalian homologs WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood"AN012747.944.00E-132"Ortholog(s) have phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, ubiquitin binding activity"
GBC42568.1g3084.t1RIR_2574700hypothetical protein-OG0002988----AN1189154.559.00E-13Putative bZIP transcription factor
GBC42570.1g3086.t1RIR_2574900phosphatidylserine decarboxylase family protein-OG0005061--------
GBC42574.1g3088.t2RIR_2575100hypothetical protein-OG0004681--------
GBC42575.1g3088.t1RIR_2575100hypothetical protein-OG0004681--------
GBC42576.1Tis13_21704RIR_2575110Tis13_21704----------
GBC42577.1Tis13_29606RIR_2575120Tis13_29606----------
GBC42578.1g3089.t1RIR_2575200hypothetical protein----------
GBC42579.1g3090.t1RIR_2575300hypothetical protein----------
GBC42580.1Tis13_94828RIR_2575310Tis13_94828----------
GBC42581.1Tis13_94827RIR_2575320Tis13_94827----------
GBC42582.1g3091.t1RIR_2575400hypothetical protein----------
GBC42583.1JEMT01029648.1_cds_EXX51527.1_28495RIR_2575410JEMT01029648.1_cds_EXX51527.1_28495--YMR068W26.778.00E-22Component of a complex containing the Tor2p kinase and other proteins; complex may have a role in regulation of cell growthAN113033.081.00E-15"Ortholog of A. nidulans FGSC A4 : AN5168, A. fumigatus Af293 : Afu6g07030, Afu4g13872, A. niger CBS 513.88 : An15g06750, An07g01930 and A. oryzae RIB40 : AO090701000916"
GBC42584.1g3092.t1RIR_2575500hypothetical protein--YFL002C39.41.00E-141Putative ATP-dependent RNA helicase; nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradientsAN317643.771.00E-146ATP-dependent rRNA helicase
GBC42585.1g3093.t1RIR_2575600serine/threonine protein kinase-OG0000000YMR230W61.762.00E-42"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10B has a paralog, RPS10A, that arose from the whole genome duplication"AN370660.422.00E-49S. cerevisiae ortholog RPS10A has role in rRNA export from nucleus; palA-dependent expression independent of pH
GBC42588.1g3095.t1RIR_2575800hypothetical protein--YGL055W41.542.00E-89Delta(9) fatty acid desaturase; required for monounsaturated fatty acid synthesis and for normal distribution of mitochondriaAN413544.382.00E-91Putative delta-9-stearic acid desaturase; converts palmitic acid and stearic acid to palmitoleic acid and oleic acid; null mutant has decreased fatty acid content; synthetically lethal with sdeA mutation
GBC42589.1Tis13_15627RIR_2575810Tis13_15627----------
GBC42590.1g3096.t1RIR_2575900hypothetical protein--YLR218C464.00E-11Twin Cx(9)C protein involved in cytochrome c oxidase organization; organization includes assembly or stability; localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; interacts genetically with CYC1 and with cytochrome c oxidase assembly factors----
GBC42591.1g3097.t1RIR_2576000hypothetical protein--YMR038C33.331.00E-11Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stressAN604537.86.00E-15"Ortholog(s) have superoxide dismutase copper chaperone activity and role in cellular copper ion homeostasis, cellular response to metal ion, intracellular copper ion transport, removal of superoxide radicals"
GBC42592.1g3098.t1RIR_2576100wd repeat protein-OG0004978YOL129W41.612.00E-30Vacuolar membrane protein of unknown function; involved in vacuolar protein sorting; also detected in the mitochondriaAN654445.456.00E-32"Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway and Vps55/Vps68 complex, fungal-type vacuole membrane localization"
GBC42593.1g3099.t1RIR_2576200bud site selection-related protein-OG0005327--------
GBC42594.1g3100.t1RIR_2576300hypothetical protein------AN231825.052.00E-24"Ortholog of A. fumigatus Af293 : Afu5g10580, A. niger CBS 513.88 : An14g04140, A. oryzae RIB40 : AO090010000479, Aspergillus wentii : Aspwe1_0106828 and Aspergillus sydowii : Aspsy1_0026806"
GBC42595.1g3101.t1RIR_2576400bzip transcription factor-OG0000143--------
GBC42596.1g3102.t1RIR_2576500putative thioredoxin peroxidase-OG0001183YAR002C-A37.684.00E-44"Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms heterotrimeric complex with Erp2p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP1 has a paralog, ERP6, that arose from the whole genome duplication"AN444652.051.00E-64"Ortholog(s) have role in ER to Golgi vesicle-mediated transport, protein retention in ER lumen and COPII-coated ER to Golgi transport vesicle localization"
GBC42597.1g3103.t1RIR_2576600Golgi protein-OG0005540YLR060W48.530"Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase; forms a tetramer with Frs2p to generate active enzyme; able to hydrolyze mis-aminoacylated tRNA-Phe, which could contribute to translational quality control"AN408655.230"Ortholog(s) have phenylalanine-tRNA ligase activity, role in cellular response to drug, phenylalanyl-tRNA aminoacylation and phenylalanine-tRNA ligase complex localization"
GBC42598.1g3104.t1RIR_2576700carbonic anhydrase-OG0000315YJL190C77.692.00E-73"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22A has a paralog, RPS22B, that arose from the whole genome duplication"AN090775.382.00E-71Ortholog(s) have structural constituent of ribosome activity and cytosolic small ribosomal subunit localization
GBC42599.1g3105.t1RIR_2576800Autophagy-related protein 13-OG0003508YLR438W50.598.00E-138"L-ornithine transaminase (OTAse); catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive; protein abundance increases in response to DNA replication stress"AN181054.843.00E-171"Ornithine transaminase, involved in utilization of arginine as a proline source; arginine-induced expression and activity; subject to carbon-catabolite and nitrogen-metabolite repression; regulated by CreA and AreA; stress-induced protein"
GBC42600.1g3106.t1RIR_2576900Alpha/beta-hydrolaseCE1OG0001674--------
GBC42601.1g3107.t1RIR_2577000RNA polymerase II transcription repair factor-OG0002630--------
GBC42602.1g3108.t1RIR_2577100Mitochondrial ribosomal protein subunit L1-OG0000879YDR462W34.092.00E-14Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress----
GBC42603.1g3109.t1RIR_2577200Peroxin-13-OG0001877YPR190C27.036.00E-14RNA polymerase III subunit C82AN827228.086.00E-22"Has domain(s) with predicted DNA binding, DNA-directed 5'-3' RNA polymerase activity and role in transcription, DNA-templated"
GBC42604.1g3110.t1RIR_2577300Actin-OG0000178--------
GBC42605.1g3111.t1RIR_2577400bud site selection-related protein-OG0002425--------
GBC42606.1g3112.t1RIR_2577500hypothetical protein-OG0001013--------
GBC42607.1g3113.t1RIR_2577600zinc finger bed domain-containing protein-OG0004766--------
GBC42608.1g3114.t1RIR_2577700zinc finger bed domain-containing protein 4-like----------
GBC42609.1g3115.t1RIR_2577800reverse transcriptase-OG0000929--------
GBC42610.1g3116.t1RIR_2577900DNA-binding wrky transcription factor-OG0001571--------
GBC42611.1g3117.t1RIR_2578000Oligosaccharyltransferase complex subunit alpha-OG0002769--------
GBC42612.1g3118.t1RIR_2578100Transcription initiation factor TFIIF subunit-OG0001665--------
GBC42613.1g3119.t1RIR_2578200transcription initiation factor tfiif subunit-OG0001665----AN871730.931.00E-22"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC42614.1g3120.t1RIR_2578300transposable element tc3 transposase-OG0000005----AN871726.051.00E-15"Has domain(s) with predicted DNA binding, nucleic acid binding activity"
GBC42616.1g3121.t1RIR_2578400CENP-b protein 1-OG0000010--------
GBC42618.1g3122.t1RIR_2578500hypothetical protein----------
GBC42619.1g3123.t1RIR_2578600galactinol synthaseGT8OG0004005--------
GBC42621.1Tis13_333869RIR_2578620Tis13_333869----------
GBC42622.1g3124.t1RIR_2578700Patatin family-OG0000615--------
GBC42623.1g3125.t1RIR_2578800galactinol synthaseGT8OG0004005--------
GBC42624.1g3126.t1RIR_2578900Saccharopine dehydrogenase-OG0003930--------
GBC42625.1g3127.t1RIR_2579000sh3 domain-binding glutamic acid-rich-like-OG0001225--------
GBC42626.1g3128.t1RIR_2579100ph-response regulator protein palc-OG0004591--------
GBC42627.1g3129.t1RIR_2579200"3-hydroxyanthranilate 3,4-dioxygenase"-OG0003296--------
GBC42628.1Tis13_86469RIR_2579210Tis13_86469----------
GBC42629.1JEMT01018679.1_cds_EXX66540.1_13490RIR_2579220JEMT01018679.1_cds_EXX66540.1_13490----------
GBC42630.1g3130.t1RIR_2579300L-gulonolactone oxidase--YHR102W23.831.00E-23"Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"AN581529.894.00E-27Aurora protein serine/threonine kinase
GBC42633.1g3132.t1RIR_2579500hypothetical protein--YGR271C-A32.74.00E-11Essential protein required for maturation of 18S rRNA; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus----
GBC42634.1g3133.t2RIR_2579600polyketide synthase-OG0003655--------
GBC42635.1g3133.t1RIR_2579600polyketide synthase-OG0003655--------
GBC42636.1g3133.t3RIR_2579600polyketide synthase-OG0003655--------
GBC42637.1g3134.t1RIR_2579700DASH complex subunit DAD2-OG0005087--------
GBC42638.1g3135.t1RIR_2579800tRNA-specific adenosine deaminase 3-OG0003607--------
GBC42639.1g3136.t1RIR_2579900DNA-directed RNA polymerase II subunit RPB4-OG0002651--------
GBC42640.1g3137.t1RIR_2580000tRNA-OG0000869--------
GBC42641.1g3138.t1RIR_2580100Exocyst complex component 3-OG0001224----AN1006627.741.00E-25Predicted mariner transposon-related ORF
GBC42642.1g3139.t1RIR_2580200Serine/threonine protein phosphatase-OG0001018--------
GBC42643.1g3140.t2_oku1RIR_2580310Vam7p-OG0000565--------
GBC42644.1g3140.t1RIR_2580300F-box and WD-40 domain protein 7-OG0000179--------
GBC42645.1g3140.t2_oku2RIR_2580300F-box and WD-40 domain protein 7-OG0000179--------
GBC42646.1g3141.t1RIR_2580400putative swi5-like protein-OG0003477--------
GBC42647.1g3142.t1RIR_2580500Centromere protein P-OG0005288--------
GBC42648.1g3143.t1RIR_2580600conserved fungal protein-OG0003931--------
GBC42649.1g3144.t2RIR_2580700Splicing factor 1-OG0000599--------
GBC42650.1g3144.t1RIR_2580700Splicing factor 1-OG0000599--------
GBC42653.1g3148.t1RIR_2581000hypothetical protein------AN1013722.098.00E-27WD domain-containing protein; NeddH-associated protein
GBC42654.1g3149.t1RIR_2581100hypothetical protein-OG0000034--------
GBC42655.1g3150.t1RIR_2581200hypothetical protein----------
GBC42658.1g3152.t1RIR_2581400hypothetical protein-OG0000008--------
GBC42663.1g3157.t1RIR_2581900hypothetical protein-OG0000026--------
GBC42664.1g3158.t1RIR_2582000ribonuclease h1-like-OG0001267--------
GBC42665.1g3159.t1RIR_2582100"ribonuclease hi, putative"-OG0000001YMR080C26.091.00E-17ATP-dependent RNA helicase of the SFI superfamily; involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; binds to the small ribosomal subunit via an interaction with Rps26; forms cytoplasmic foci upon DNA replication stressAN724630.41.00E-41"Has domain(s) with predicted ATP binding, nucleoside-triphosphatase activity, nucleotide binding activity"
GBC42668.1JEMT01027736.1_cds_EXX56411.1_23616RIR_2582310JEMT01027736.1_cds_EXX56411.1_23616----------
GBC42671.1g3164.t1RIR_2582600exodeoxyribonuclease III----------
GBC42672.1g3165.t1RIR_2582700RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC42673.1g3166.t1RIR_2582800hypothetical protein----------
GBC42674.1g3167.t1RIR_2582900Succinate dehydrogenase (ubiquinone) iron-sulfur-OG0002506--------
GBC42675.1g3168.t1RIR_2583000Autophagy-related protein 18-OG0000559YOR299W32.932.00E-58"Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BUD7 has a paralog, BCH1, that arose from the whole genome duplication"AN312242.330Transcript levels increase during the unfolded-protein response (UPR); S. cerevisiae ortholog of Bch1p
GBC42676.1g3169.t1RIR_2583100bzip transcription factor-OG0000762--------
GBC42678.1g3171.t1RIR_25833001-phosphatidylinositol 3-phosphate--YPL147W38.321.00E-143"Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa2p"AN1007847.510"Ortholog(s) have ATPase activity, coupled to transmembrane movement of substances activity, role in fatty acid transport and integral component of peroxisomal membrane, peroxisomal importomer complex localization"
GBC42679.1g3172.t1RIR_2583400hypothetical protein--YPL147W38.321.00E-143"Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa2p"AN1007847.510"Ortholog(s) have ATPase activity, coupled to transmembrane movement of substances activity, role in fatty acid transport and integral component of peroxisomal membrane, peroxisomal importomer complex localization"
GBC42680.1Tis13_36627RIR_2583410Tis13_36627----------
GBC42681.1g3173.t1RIR_2583500serine/threonine-protein kinase-OG0000184--------
GBC42682.1g3174.t1RIR_2583600hypothetical protein------AN094751.476.00E-116"Protein required for the synthesis of precursor Z, an intermediate in the molybdopterin cofactor biosynthesis pathway; molybdopterin cofactor is required for the activity of nitrate reductase"
GBC42683.1Tis13_30501RIR_2583610Tis13_30501-OG0000077YKR060W31.735.00E-19Putative subunit of U3-containing 90S preribosome complex; complex is involved in production of 18S rRNA and assembly of small ribosomal subunitAN669832.785.00E-39"Has domain(s) with predicted RNA binding, structural constituent of ribosome activity, role in translation and large ribosomal subunit localization"
GBC42685.1g3175.t1RIR_2583700hypothetical protein--YCR047C57.246.00E-103Methyltransferase; methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; diploid mutant displays random budding patternAN578951.223.00E-89Ortholog(s) have rRNA (guanine) methyltransferase activity
GBC42686.1g3176.t1RIR_2583800RNA-directed DNA polymerase from mobile element-OG0000001----AN313555.883.00E-13"Ortholog of A. fumigatus Af293 : Afu3g13040, A. niger CBS 513.88 : An02g08930, A. oryzae RIB40 : AO090012000826, Aspergillus wentii : Aspwe1_0050040 and Aspergillus sydowii : Aspsy1_0087186"
GBC42690.1g3180.t1RIR_2584200hypothetical protein-OG0000077----AN221827.113.00E-13"Has domain(s) with predicted magnesium ion transmembrane transporter activity, role in magnesium ion transport and integral component of membrane localization"
GBC42691.1g3181.t1RIR_2584300component of a complex containing the tor2p-OG0000017--------
GBC42692.1g3182.t1RIR_2584400ATP-dependent RNA helicase DDX55/SPB4-OG0000240YDL108W42.951.00E-70"Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia"AN828537.316.00E-41Predicted cyclin-dependent protein kinase activating kinase; mutant is lethal with enlarged vacuoles and swollen hyphae
GBC42693.1g3183.t1RIR_258450040s ribosomal protein s10-OG0000990YOR074C68.924.00E-153Thymidylate synthase; required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/SAN702864.445.00E-141Putative thymidylate synthase with a predicted role in pyrimidine metabolism
GBC42694.1g3184.t1RIR_2584600Bud site selection protein 31-OG0001719----AN244648.084.00E-13"Ortholog(s) have DNA-directed DNA polymerase activity, role in DNA strand elongation involved in DNA replication, DNA synthesis involved in UV-damage excision repair and delta DNA polymerase complex localization"
GBC42695.1g3185.t1RIR_2584700oxysterol binding protein-OG0001493YOL115W36.762.00E-56"Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia"AN569431.171.00E-42Putative poly(A) RNA polymerase; required for mRNA 3'-end processing
GBC42696.1g3186.t1RIR_2584800Stearoyl-CoA desaturase-OG0000386----AN271735.815.00E-93Putative RNA-directed RNA polymerase
GBC42697.1Tis13_294361RIR_2584810Tis13_294361----------
GBC42698.1g3187.t1RIR_2584900mitochondrial respiratory chain complex assembly-OG0003698YPL153C26.146.00E-16DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxiaAN769529.151.00E-15Putative protein kinase; reduced growth on AVICEL medium; required for CreA derepression and endocellulase production
GBC42699.1g3188.t1RIR_2585000superoxide dismutase copper chaperone-OG0000652--------
GBC42700.1g3189.t1RIR_2585100protein-vacuolar targeting-related protein-OG0001239--------
GBC42701.1g3190.t1RIR_2585200hypothetical protein-OG0005808--------
GBC42702.1g3191.t1RIR_2585300sh3 domain protein-OG0000199--------
GBC42703.1g3192.t1RIR_2585400"wd domain, g-beta repeat-containing protein"-OG0005298--------
GBC42704.1g3193.t1RIR_2585500copii-coated vesicle component-OG0000809--------
GBC42705.1g3194.t1RIR_2585600Phenylalanyl-tRNA synthetase subunit beta chain-OG0002602----AN583036.077.00E-39"Has domain(s) with predicted hydrolase activity, hydrolase activity, acting on acid halide bonds, in C-halide compounds, phosphoglycolate phosphatase activity and role in metabolic process"
GBC42706.1g3195.t1RIR_2585700Ribosomal 40S subunit protein S22-OG0001185YCR014C28.955.00E-20DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase betaAN123141.542.00E-87"Has domain(s) with predicted DNA binding, DNA polymerase activity, DNA-directed DNA polymerase activity, role in DNA repair and nucleus localization"
GBC42707.1g3196.t1RIR_2585800Ornithine-oxo-acid transaminase-OG0002881--------
GBC42708.1g3197.t1RIR_2585900hypothetical protein-OG0004826--------
GBC42709.1g3197.t2RIR_2585900hypothetical protein-OG0004826--------
GBC42710.1g3198.t1RIR_2586000Mitochondrial ribosomal protein subunit L28-OG0004433--------
GBC42711.1g3199.t1RIR_2586100DNA-directed RNA polymerase III subunit RPC3-OG0001414YER058W36.673.00E-11Protein required for assembly of cytochrome c oxidase----
GBC42712.1g3200.t1RIR_2586200hypothetical protein--YKL072W32.343.00E-40"Protein that binds Sin3p in a two-hybrid assay; STB6 has a paralog, STB2, that arose from the whole genome duplication"AN043038.661.00E-66"Ortholog of S. cerevisiae : STB6, A. fumigatus Af293 : Afu1g04480, A. niger CBS 513.88 : An01g03630, A. oryzae RIB40 : AO090003000868 and Aspergillus wentii : Aspwe1_0103827"
GBC42713.1g3201.t1RIR_2586300ATP-dependent DNA helicase pif1-like-OG0000279YJR040W37.715.00E-146"Voltage-gated chloride channel; localized to the golgi, the endosomal system, and plasma membrane; involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels; modulates TBSV model (+) RNA virus replication by regulating copper metabolism"AN230858.680"Has domain(s) with predicted ion channel activity, voltage-gated chloride channel activity, role in chloride transport, transmembrane transport and membrane localization"
GBC42714.1JEMT01029449.1_cds_EXX52125.1_27900RIR_2586310JEMT01029449.1_cds_EXX52125.1_27900----------
GBC42715.1g3202.t1RIR_2586400ATP-dependent DNA helicase pif1-OG0000279YHR190W40.576.00E-92Farnesyl-diphosphate farnesyl transferase (squalene synthase); joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathwayAN1039644.356.00E-106"Ortholog(s) have farnesyl-diphosphate farnesyltransferase activity, squalene synthase activity and role in ergosterol biosynthetic process, establishment or maintenance of cell polarity"
GBC42716.1g3203.t1RIR_2586500ATP-dependent DNA helicase rrm3-like----------
GBC42720.1JEMT01017751.1_cds_EXX67433.1_12596RIR_2586620JEMT01017751.1_cds_EXX67433.1_12596----------
GBC42721.1g3205.t1RIR_2586700CENP-b protein 1-OG0000010--------
GBC42722.1g3206.t1RIR_2586800CENP-b protein 1-OG0000010--------
GBC42723.1JEMT01017876.1_cds_EXX67275.1_12749RIR_2586810JEMT01017876.1_cds_EXX67275.1_12749----------
GBC42725.1g3208.t1RIR_2587000hypothetical protein--YBR081C41.12.00E-37Subunit of the SAGA transcriptional regulatory complex; involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complexAN489444.241.00E-38Subunit of the SAGA transcriptional regulatory complex
GBC42726.1g3209.t1RIR_2587100transposase orfb--YJL080C24.347.00E-69"Essential RNA-binding G protein effector of mating response pathway; ligand-activated RNA-binding protein that delivers RNAs involved in polarization and perpetualizing mating signal to shmoo tip during pheromone signaling; Scp160p-mediated RNA trafficking essential for chemotropism and successful mating; mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins"AN206828.583.00E-141"Ortholog(s) have cytoplasmic stress granule, endoplasmic reticulum, polysome localization"
GBC42727.1g3210.t1RIR_2587200hypothetical protein--YJL080C24.348.00E-69"Essential RNA-binding G protein effector of mating response pathway; ligand-activated RNA-binding protein that delivers RNAs involved in polarization and perpetualizing mating signal to shmoo tip during pheromone signaling; Scp160p-mediated RNA trafficking essential for chemotropism and successful mating; mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins"AN206828.132.00E-141"Ortholog(s) have cytoplasmic stress granule, endoplasmic reticulum, polysome localization"
GBC42728.1JEMT01017876.1_cds_EXX67280.1_12754RIR_2587210JEMT01017876.1_cds_EXX67280.1_12754----------
GBC42730.1g3212.t1RIR_2587400cell cycle checkpoint protein rad17--YPL001W32.067.00E-51Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex; uses the cofactor acetyl coenzyme A to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repairAN621430.462.00E-56Putative Hat1 acetyltransferase
GBC42736.1JEMT01027425.1_cds_EXX57218.1_22812RIR_2587910JEMT01027425.1_cds_EXX57218.1_22812----------
GBC42738.1g3219.t1RIR_2588100map kinase kinase ste7-OG0000000--------
GBC42740.1g3221.t1RIR_2588300U4/U6 small nuclear ribonucleoprotein PRP3-OG0003121YDR523C28.424.00E-14Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by themAN567427.333.00E-14"MAP kinase, kinase, kinase, kinase (MAPKKKK); mutants undergo premature but incomplete sexual development"
GBC42741.1g3222.t1RIR_2588400rRNA-processing protein efg1-OG0004302--------
GBC42742.1g3223.t1RIR_2588500highly derived d5-like helicase-primase----------
GBC42745.1g3226.t1RIR_2588800hypothetical protein--YAR019C28.877.00E-17Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stressAN1015329.942.00E-14Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC42748.1g3229.t1RIR_2589100zinc finger bed domain-containing protein-OG0000008--------
GBC42749.1g3230.t1RIR_2589200transposable element tc3 transposase-OG0000005--------
GBC42756.1g3236.t1RIR_2589800hypothetical protein-OG0000034--------
GBC42757.1g3237.t1RIR_2589900RNA-directed DNA polymerase from mobile element----------
GBC42761.1g3240.t1RIR_259020040S ribosomal protein s25-OG0003840YOL016C27.231.00E-14"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication"AN427929.64.00E-19Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea
GBC42762.1g3241.t1RIR_2590300zinc finger bed domain-containing protein-OG0000008--------
GBC42764.1g3242.t1RIR_2590400transcription factor e2f6-OG0000008--------
GBC42765.1g3243.t1RIR_2590500nucleotidyltransferase--YOR231W26.542.00E-11"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN1015326.153.00E-12Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC42766.1g3244.t1RIR_2590600qwrf motif-containing protein 2-like-OG0006218--------
GBC42767.1g3245.t1RIR_2590700protein rcc2 homolog-OG0000005YLR362W26.969.00E-13"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress"AN581526.632.00E-11Aurora protein serine/threonine kinase
GBC42768.1g3246.t1RIR_2590800hypothetical protein----------
GBC42769.1g3247.t1RIR_2590900"ef-hand calcium-binding protein,"-OG0000072--------
GBC42770.1g3248.t1RIR_2591000Mitochondrial inner membrane organizing system-OG0001774--------
GBC42771.1g3249.t1RIR_2591100rhomboid family protease-OG0004416----AN271731.141.00E-77Putative RNA-directed RNA polymerase
GBC42772.1g3250.t1RIR_2591200ribonuclease p protein subunit p25-like protein-OG0004837--------
GBC42773.1g3251.t1RIR_2591300nfx1-type zinc finger protein-containing-OG0000314--------
GBC42774.1g3252.t1RIR_2591400hypothetical protein----------
GBC42775.1g3253.t1RIR_2591500metal ion transport-related protein-OG0001351--------
GBC42776.1g3254.t1RIR_2591600CENP-b protein 1-OG0000010YDL159W27.743.00E-19Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathwayAN581530.324.00E-23Aurora protein serine/threonine kinase
GBC42777.1g3255.t1RIR_2591700tigger transposable element-derived protein-OG0000010--------
GBC42778.1g3256.t1RIR_2591800pogo transposable element with krab domain-OG0000105--------
GBC42779.1g3257.t1RIR_2591900RNA-directed DNA polymerase from mobile element-OG0000001--------
GBC42780.1g3258.t1RIR_2592000RNA-directed DNA polymerase from mobile element-OG0000001YDR523C26.145.00E-14Putative protein serine/threonine kinase; expressed at the end of meiosis; localized to nucleus and cytoplasm; required for efficient spore packaging and correct localization of enzymes involved in spore wall synthesis; member of the GCKIII subfamily of STE20 family kinases; multiply phosphorylated on serine and threonine residues; interacts genetically and physically with 14-3-3 proteins Bmh1p and Bmh2p and may be regulated by themAN1015326.458.00E-13Mitogen activated protein kinase kinase kinase (MAPKKK) of the HOG signaling pathway that regulates osmotic stress response; mutants show growth inhibition in 1.5 M sucrose and sensitivity to NaCl
GBC42782.1g3260.t1RIR_2592200Partner of Y14 and mago-OG0004596--------
GBC42783.1g3261.t1RIR_2592300Chs5-Arf1p-binding protein BUD7/BCH1-OG0003158--------
GBC42784.1g3262.t1RIR_2592400hypothetical protein-OG0005770--------
GBC42785.1g3263.t1RIR_2592500DnaJ homolog subfamily B member 12-OG0000955--------
GBC42786.1g3264.t2RIR_2592600"ATP-binding cassette, subfamily D (ALD),"-OG0000504--------
GBC42787.1g3264.t1RIR_2592600"ATP-binding cassette, subfamily D (ALD),"-OG0000504--------
GBC42788.1g3265.t1RIR_2592700hypothetical protein-OG0000199--------
GBC42789.1g3266.t1RIR_2592800hypothetical protein----------
GBC42790.1g3267.t1RIR_2592900Molybdenum cofactor biosynthesis protein C-OG0002017--------
GBC42791.1g3268.t1RIR_2593000Ribosome biogenesis protein UTP30-OG0001501--------
GBC42792.1g3269.t2RIR_259310018S rRNA (guanine1575-N7)-methyltransferase-OG0002560--------
GBC42793.1g3269.t1RIR_259310018S rRNA (guanine1575-N7)-methyltransferase-OG0002560--------
GBC42794.1g3270.t1RIR_2593200duf1168 domain-containing protein-OG0003431--------
GBC42795.1g3271.t1RIR_259330020S proteasome subunit beta 1-OG0001766YOR231W33.336.00E-15"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN597329.286.00E-13Protein with similarity to protein kinase C; involved in polar axis establishment and germling growth; mutant is inviable and forms microcolonies
GBC42796.1g3272.t1RIR_2593400trapp complex subunit trs120-OG0002422--------
GBC42797.1g3272.t2RIR_2593400trapp complex subunit trs120-OG0002422YDR495C25.462.00E-20"Component of CORVET membrane tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase"AN076326.336.00E-34Putative CORVET complex protein involved in vacuolar protein sorting
GBC42798.1g3273.t1RIR_2593500hypothetical protein-OG0007067--------
GBC42799.1g3273.t2RIR_2593500hypothetical protein-OG0007067--------
GBC42800.1g3274.t1RIR_2593600Cyclin-dependent kinase 7-OG0000057--------
GBC42801.1g3275.t1RIR_2593700Thymidylate synthase-OG0001889YHR072W-A68.971.00E-22Subunit of box H/ACA snoRNP complex; required for pseudouridylation and processing of pre-18S rRNAAN825469.351.00E-25Putative snoRNP complex protein; ortholog of S. cerevisiae Nop10p; expression reduced after exposure to farnesol
GBC42802.1g3276.t1RIR_2593800DNA polymerase delta subunit 4-OG0003399YKL047W25.338.00E-32"Putative protein of unknown function; may have a role in lipid metabolism, based on localization to lipid droplets; predicted to be palmitoylated"AN085028.45.00E-47Ortholog(s) have lipid droplet localization
GBC42803.1g3277.t1RIR_2593900putative Non-canonical poly(A) RNA polymerase-OG0000863YLR087C27.82.00E-126"Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"AN632931.724.00E-163"Ortholog(s) have role in fermentation, protein maturation"
GBC42804.1g3278.t1RIR_2594000RNA-dependent RNA polymerase-OG0000538YPL140C25.938.00E-13"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"AN427928.814.00E-12Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea
GBC42805.1g3279.t1RIR_2594100hypothetical protein----------
GBC42806.1g3280.t1RIR_2594200serine/threonine protein kinase----------
GBC42807.1g3281.t1RIR_2594300hypothetical protein--YPL140C23.881.00E-12"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication"----
GBC42808.1g3282.t1RIR_2594400hypothetical protein-OG0002714YOR231W26.182.00E-16"MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication"AN427927.936.00E-12Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea
GBC42810.1g3283.t1RIR_2594500hypothetical protein--YPL153C27.694.00E-15DNA damage response protein kinase; required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication; activates the downstream kinase Dun1p; differentially senses mtDNA depletion and mitochondrial ROS; required for regulation of copper genes in response to DNA-damaging agents; relocalizes to cytosol in response to hyoxiaAN427926.557.00E-11Putative a2+/calmodulin-dependent protein kinase; role in the response to DNA damage; mutants sensitive to hydroxyurea