GBC54231.1

Protein

Length

438 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
133 - 432
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 350 400 438

Detailed signature matches

IPR016040

NAD(P)-binding domain
1. PF16363 (GDP_Man_Dehyd)
  
  139 - 429
  
  Pfam
  PF16363 (GDP_Man_Dehyd)
2. SSF51735 (NAD(P)-bi...)
  
  133 - 432
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)

no IPR

Unintegrated signatures

cd05230 (UGD_SDR_e)

136 - 431

CDD
cd05230 (UGD_SDR_e)

Residue annotation

NAD binding site c...

142G

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

144A

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

145G

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

146F

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

147V

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

166D

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

167N

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

168F

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

169F

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

170T

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

171G

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

190H

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

191D

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

192V

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

206L

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

207A

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

208C

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

209P

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

210A

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

225T

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

247T

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

248S

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

249T

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

278Y

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

282K

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

305I

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

306F

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

307N

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

308T

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)

319R

NAD binding site
142G, 144A, 145G, 146F, 147V, 166D, 167N, 168F, 169F, 170T, 171G, 190H, 191D, 192V, 206L, 207A, 208C, 209P, 210A, 225T, 247T, 248S, 249T, 278Y, 282K, 305I, 306F, 307N, 308T, 319R
CDD
cd05230 (UGD_SDR_e)
putative substrate...

195P

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

196F

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

231I

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

232N

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

235G

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

236L

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

238K

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

239R

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)

292Y

putative substrate binding site 2
195P, 196F, 231I, 232N, 235G, 236L, 238K, 239R, 292Y
CDD
cd05230 (UGD_SDR_e)
putative substrate...

212P

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

275R

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

307N

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

318G

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

319R

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

320V

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

323N

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

324F

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

335T

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

336I

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

337Y

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

342Q

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

344R

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

378I

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

404D

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)

408R

putative substrate binding site 1
212P, 275R, 307N, 318G, 319R, 320V, 323N, 324F, 335T, 336I, 337Y, 342Q, 344R, 378I, 404D, 408R
CDD
cd05230 (UGD_SDR_e)
active site cd05230

226S

active site
226S, 249T, 278Y, 282K
CDD
cd05230 (UGD_SDR_e)

249T

active site
226S, 249T, 278Y, 282K
CDD
cd05230 (UGD_SDR_e)

278Y

active site
226S, 249T, 278Y, 282K
CDD
cd05230 (UGD_SDR_e)

282K

active site
226S, 249T, 278Y, 282K
CDD
cd05230 (UGD_SDR_e)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC54231.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component