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Protein

GBC53752.1

Length

611 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
7 - 294
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
431 - 611
3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (IPR001104)

1 100 200 300 400 500 611

Detailed signature matches

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

7 - 294

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

IPR000719

Protein kinase domain

SM00220 (serkin_6)

10 - 270

SMART
SM00220 (serkin_6)
PS50011 (PROTEIN_KI...)

10 - 270

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)
PF00069 (Pkinase)

10 - 270

Pfam
PF00069 (Pkinase)

IPR001104

3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal

PS50244 (S5A_REDUCTASE)

473 - 586

PROSITE profiles
PS50244 (S5A_REDUCTASE)
PF02544 (Steroid_dh)

527 - 611

Pfam
PF02544 (Steroid_dh)

431 - 503

Pfam
PF02544 (Steroid_dh)

IPR017441

Protein kinase, ATP binding site

PS00107 (PROTEIN_KI...)

16 - 39

PROSITE patterns
PS00107 (PROTEIN_KINASE_ATP)

IPR008271

Serine/threonine-protein kinase, active site

PS00108 (PROTEIN_KI...)

129 - 141

PROSITE patterns
PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

cd05117 (STKc_CAMK)

9 - 269

CDD
cd05117 (STKc_CAMK)

Residue annotation

ATP binding site c...

16L

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

17G

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

18Q

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

19G

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

24V

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

37A

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

39K

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

71L

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

87T

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

88D

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

89W

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

90A

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

94E

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

137E

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

138N

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

140L

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

153A

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)

154D

ATP binding site
16L, 17G, 18Q, 19G, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 137E, 138N, 140L, 153A, 154D
CDD
cd05117 (STKc_CAMK)
active site cd05117

16L

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

17G

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

18Q

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

19G

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

20T

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

24V

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

37A

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

39K

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

71L

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

87T

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

88D

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

89W

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

90A

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

94E

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

96F

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

132R

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

133D

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

135K

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

137E

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

138N

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

140L

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

153A

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

154D

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

157L

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

173C

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

174G

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

175T

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

176P

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

177G

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

179M

active site
16L, 17G, 18Q, 19G, 20T, 24V, 37A, 39K, 71L, 87T, 88D, 89W, 90A, 94E, 96F, 132R, 133D, 135K, 137E, 138N, 140L, 153A, 154D, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)
polypeptide substr...

20T

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

94E

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

96F

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

132R

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

133D

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

135K

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

137E

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

157L

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

173C

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

174G

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

175T

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

176P

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

177G

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)

179M

polypeptide substrate binding site
20T, 94E, 96F, 132R, 133D, 135K, 137E, 157L, 173C, 174G, 175T, 176P, 177G, 179M
CDD
cd05117 (STKc_CAMK)
activation loop (A...

153A

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

154D

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

155F

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

156G

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

157L

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

158S

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

159R

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

160I

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

161I

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

173C

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

174G

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

175T

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

176P

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

177G

activation loop (A-loop)
153A, 154D, 155F, 156G, 157L, 158S, 159R, 160I, 161I, 173C, 174G, 175T, 176P, 177G
CDD
cd05117 (STKc_CAMK)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0006629 lipid metabolic process

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors

Cellular Component

GO:0005737 cytoplasm
GO:0016021 integral component of membrane