GBC53173.1

Protein

Length

319 amino acids

Protein family membership

Inositol monophosphatase-like (IPR000760)
- Inositol monophosphatase (IPR033942)

Domains and repeats

None predicted.

Detailed signature matches

IPR000760

Inositol monophosphatase-like
1. PF00459 (Inositol_P)
  
  7 - 287
  
  Pfam
  PF00459 (Inositol_P)
2. PR00377 (IMPHPHTASES)
  
  213 - 234
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  48 - 68
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  95 - 111
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  244 - 268
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  70 - 86
  
  PRINTS
  PR00377 (IMPHPHTASES)
IPR033942

Inositol monophosphatase
1. cd01639 (IMPase)
  
  10 - 285
  
  CDD
  cd01639 (IMPase)
IPR020583

Inositol monophosphatase, metal-binding site
1. PS00629 (IMP_1)
  
  95 - 108
  
  PROSITE patterns
  PS00629 (IMP_1)

no IPR

Unintegrated signatures

SSF56655 (Carbohydr...)

6 - 308

SUPERFAMILY
SSF56655 (Carbohydrate phosphatase)

Residue annotation

active site cd01639

42K

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

48D

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

54D

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

77E

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

78E

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

98D

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

99P

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

100I

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

101D

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

102G

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

103T

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

247W

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)

248D

active site
42K, 48D, 54D, 77E, 78E, 98D, 99P, 100I, 101D, 102G, 103T, 247W, 248D
CDD
cd01639 (IMPase)
dimerization inter...

47S

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

49L

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

104T

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

105N

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

107I

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

108H

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

109W

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

110F

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

111P

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

112F

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

172Q

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

173C

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

174L

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

176V

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

178E

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

179Y

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

188L

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

189G

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

192F

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

195V

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

196H

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

199M

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

216R

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

217G

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

218I

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

219R

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

220S

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

221L

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

222G

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

230Q

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

234G

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

235E

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

236A

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

237D

dimerization interface
47S, 49L, 104T, 105N, 107I, 108H, 109W, 110F, 111P, 112F, 172Q, 173C, 174L, 176V, 178E, 179Y, 188L, 189G, 192F, 195V, 196H, 199M, 216R, 217G, 218I, 219R, 220S, 221L, 222G, 230Q, 234G, 235E, 236A, 237D
CDD
cd01639 (IMPase)

GO term prediction

Biological Process

GO:0046854 phosphatidylinositol phosphorylation
GO:0046855 inositol phosphate dephosphorylation

Molecular Function

GO:0008934 inositol monophosphate 1-phosphatase activity

Cellular Component