GBC48638.1

Protein

Length

703 amino acids

Protein family membership

NAD(+) synthetase (IPR003694)
- Glutamine-dependent NAD(+) synthetase (IPR014445)

Domains and repeats

Domain
5 - 293
Carbon-nitrogen hydrolase (IPR003010)
341 - 603
NAD/GMP synthase (IPR022310)

1 100 200 300 400 500 600 703

Detailed signature matches

IPR003694

NAD(+) synthetase
1. cd00553 (NAD_synthase)
  
  330 - 654
  
  CDD
  cd00553 (NAD_synthase)
2. TIGR00552
  
  418 - 603
  
  TIGRFAMs
  TIGR00552 (TIGR00552)
IPR014445

Glutamine-dependent NAD(+) synthetase
1. PIRSF006630 (NADS_GAT)
  
  3 - 688
  
  PIRSF
  PIRSF006630 (NADS_GAT)
IPR003010

Carbon-nitrogen hydrolase
1. PS50263 (CN_HYDROLASE)
  
  5 - 293
  
  PROSITE profiles
  PS50263 (CN_HYDROLASE)
2. SSF56317 (Carbon-ni...)
  
  5 - 288
  
  SUPERFAMILY
  SSF56317 (Carbon-nitrogen hydrolase)
3. PF00795 (CN_hydrolase)
  
  6 - 281
  
  Pfam
  PF00795 (CN_hydrolase)
IPR022310

NAD/GMP synthase
1. PF02540 (NAD_synthase)
  
  341 - 603
  
  Pfam
  PF02540 (NAD_synthase)

no IPR

Unintegrated signatures

SSF52402 (Adenine n...)

410 - 666

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)

319 - 380

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)
cd07570 (GAT_Gln-NA...)

6 - 286

CDD
cd07570 (GAT_Gln-NAD-synth)

Residue annotation

multimer interface...

16A

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

17L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

18D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

19F

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

20E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

53C

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

54L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

55D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

56H

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

58L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

59E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

60G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

61D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

64L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

91V

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

96K

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

97Y

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

116F

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

117L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

121G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

122N

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

124R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

126L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

127R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

130S

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

131A

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

133S

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

178L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

180T

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

181P

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

182N

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

186I

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

187S

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

189G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

192G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

204H

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

205E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

206L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

207R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

210Y

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

214D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

217K

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

218E

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

221L

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

222K

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

235C

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

236D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

237G

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

238D

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

239R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

241Y

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

260Q

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

279R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

281H

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)

282R

multimer interface
16A, 17L, 18D, 19F, 20E, 53C, 54L, 55D, 56H, 58L, 59E, 60G, 61D, 64L, 91V, 96K, 97Y, 116F, 117L, 118A, 120D, 121G, 122N, 124R, 126L, 127R, 130S, 131A, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 189G, 192G, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 236D, 237G, 238D, 239R, 241Y, 260Q, 279R, 281H, 282R
CDD
cd07570 (GAT_Gln-NAD-synth)
catalytic triad cd...

45E

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)

114K

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)

175C

catalytic triad
45E, 114K, 175C
CDD
cd07570 (GAT_Gln-NAD-synth)
active site cd07570

45E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

114K

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

123Y

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

125E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

175C

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)

208K

active site
45E, 114K, 118A, 120D, 123Y, 125E, 175C, 176E, 179F, 208K
CDD
cd07570 (GAT_Gln-NAD-synth)
protein interface ...

116F

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

117L

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

118A

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

120D

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

121G

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

122N

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

124R

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

133S

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

176E

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

178L

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

179F

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

180T

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

181P

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

182N

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

186I

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

187S

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

204H

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

205E

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

206L

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

207R

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

210Y

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

214D

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

217K

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

218E

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

221L

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

222K

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

235C

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

237G

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

238D

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

239R

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

241Y

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

260Q

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)

281H

protein interface 1
116F, 117L, 118A, 120D, 121G, 122N, 124R, 133S, 176E, 178L, 179F, 180T, 181P, 182N, 186I, 187S, 204H, 205E, 206L, 207R, 210Y, 214D, 217K, 218E, 221L, 222K, 235C, 237G, 238D, 239R, 241Y, 260Q, 281H
CDD
cd07570 (GAT_Gln-NAD-synth)
homodimer interfac...

337G

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

338P

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

341W

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

344D

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

345Y

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

446Y

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

447H

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

448I

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

449D

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

452M

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

453N

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

456V

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

457T

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

485A

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

489I

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

492R

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

493L

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

495M

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

496I

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

497L

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

499Y

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

500L

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

501F

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

503Q

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

504L

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

533K

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

534Y

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

537S

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

538S

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

539A

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

540D

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

541I

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

542N

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

545G

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

546G

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

652H

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)

654M

homodimer interface
337G, 338P, 341W, 344D, 345Y, 446Y, 447H, 448I, 449D, 452M, 453N, 456V, 457T, 485A, 489I, 492R, 493L, 495M, 496I, 497L, 499Y, 500L, 501F, 503Q, 504L, 533K, 534Y, 537S, 538S, 539A, 540D, 541I, 542N, 545G, 546G, 652H, 654M
CDD
cd00553 (NAD_synthase)
NAD binding pocket...

356L

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

357P

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

358L

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

359S

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

364S

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

421C

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

422Y

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

423M

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

484L

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

488N

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

491A

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

492R

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

494R

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

520S

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

525E

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

530Y

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

531L

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

532T

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

533K

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

536C

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

577T

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

578A

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

580L

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

594D

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

652H

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)

653K

NAD binding pocket
356L, 357P, 358L, 359S, 364S, 421C, 422Y, 423M, 484L, 488N, 491A, 492R, 494R, 520S, 525E, 530Y, 531L, 532T, 533K, 536C, 577T, 578A, 580L, 594D, 652H, 653K
CDD
cd00553 (NAD_synthase)
ATP binding pocket...

357P

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

358L

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

359S

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

363D

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

364S

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

422Y

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

423M

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

494R

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

520S

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

549K

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

576P

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)

577T

ATP binding pocket
357P, 358L, 359S, 363D, 364S, 422Y, 423M, 494R, 520S, 549K, 576P, 577T
CDD
cd00553 (NAD_synthase)
Mg binding site cd...

359S

Mg binding site
359S, 363D, 525E, 577T
CDD
cd00553 (NAD_synthase)

363D

Mg binding site
359S, 363D, 525E, 577T
CDD
cd00553 (NAD_synthase)

525E

Mg binding site
359S, 363D, 525E, 577T
CDD
cd00553 (NAD_synthase)

577T

Mg binding site
359S, 363D, 525E, 577T
CDD
cd00553 (NAD_synthase)
active-site loop c...

430K

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

573N

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

574A

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

575I

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

576P

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

577T

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

578A

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

579E

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

580L

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

588V

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

589Q

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

590A

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

591D

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

592E

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

593V

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

594D

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

595M

active-site loop
430K, 573N, 574A, 575I, 576P, 577T, 578A, 579E, 580L, 588V, 589Q, 590A, 591D, 592E, 593V, 594D, 595M
CDD
cd00553 (NAD_synthase)

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process
GO:0009435 NAD biosynthetic process

Molecular Function

GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.

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Entry type

Status

Per-residue features