Filter view on

Protein

GBC48373.1

Length

506 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 70
U box domain (IPR003613)
Domain
67 - 132
Pre-mRNA-splicing factor 19 (IPR013915)
209 - 500
WD40-repeat-containing domain (IPR017986)
Repeat
192 - 241
WD40 repeat (IPR001680)
244 - 288
WD40 repeat (IPR001680)
293 - 332
WD40 repeat (IPR001680)
337 - 385
WD40 repeat (IPR001680)
379 - 420
WD40 repeat (IPR001680)
421 - 459
WD40 repeat (IPR001680)
462 - 501
WD40 repeat (IPR001680)

1 50 100 150 200 250 300 350 400 450 506

Detailed signature matches

IPR003613

U box domain

PS51698 (U_BOX)

1 - 70

PROSITE profiles
PS51698 (U_BOX)
SM00504 (Ubox_2)

1 - 67

SMART
SM00504 (Ubox_2)

IPR013915

Pre-mRNA-splicing factor 19

PF08606 (Prp19)

67 - 132

Pfam
PF08606 (Prp19)

IPR017986

WD40-repeat-containing domain

SSF50978 (WD40 repe...)

210 - 500

SUPERFAMILY
SSF50978 (WD40 repeat-like)
PS50294 (WD_REPEATS...)

209 - 427

PROSITE profiles
PS50294 (WD_REPEATS_REGION)

IPR001680

WD40 repeat

SM00320 (WD40_4)

462 - 501

SMART
SM00320 (WD40_4)

293 - 332

SMART
SM00320 (WD40_4)

421 - 459

SMART
SM00320 (WD40_4)

337 - 376

SMART
SM00320 (WD40_4)

244 - 288

SMART
SM00320 (WD40_4)

379 - 418

SMART
SM00320 (WD40_4)

192 - 241

SMART
SM00320 (WD40_4)
PS50082 (WD_REPEATS_2)

353 - 385

PROSITE profiles
PS50082 (WD_REPEATS_2)

386 - 420

PROSITE profiles
PS50082 (WD_REPEATS_2)
PF00400 (WD40)

381 - 418

Pfam
PF00400 (WD40)

247 - 287

Pfam
PF00400 (WD40)

IPR019775

WD40 repeat, conserved site

PS00678 (WD_REPEATS_1)

363 - 377

PROSITE patterns
PS00678 (WD_REPEATS_1)

no IPR

Unintegrated signatures

Coil

116 - 136

COILS
Coil (Coil)
SSF57850 (RING/U-box)

1 - 53

SUPERFAMILY
SSF57850 (RING/U-box)
cd00200 (WD40)

209 - 500

CDD
cd00200 (WD40)

Residue annotation

structural tetrad ...

209H

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

230T

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

234D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

240L

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

241N

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

253G

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

254H

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

277T

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

281D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

287W

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

288Q

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

302A

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

303H

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

320V

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

325D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

331H

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

332D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

347V

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

364G

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

369D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

375W

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

376D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

388D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

389H

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

407T

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

411Y

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

417W

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

418D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

430L

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

431D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

449G

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

454D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

458Y

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

459Q

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

471D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

472N

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

490V

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

494D

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

500Y

structural tetrad
209H, 230T, 234D, 240L, 241N, 253G, 254H, 277T, 281D, 287W, 288Q, 302A, 303H, 320V, 325D, 331H, 332D, 347V, 364G, 369D, 375W, 376D, 388D, 389H, 407T, 411Y, 417W, 418D, 430L, 431D, 449G, 454D, 458Y, 459Q, 471D, 472N, 490V, 494D, 500Y
CDD
cd00200 (WD40)

GO term prediction

Biological Process

GO:0016567 protein ubiquitination

Molecular Function

GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding

Cellular Component