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Entry type
Status
Per-residue features
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Protein
GBC46177.1
Length
2,314 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain587 - 829
- Endonuclease/exonuclease/phosphatase (IPR005135)
1,819 - 1,964- Ribonuclease H-like domain (IPR012337)
- Ribonuclease H domain (IPR002156)
1
500
1000
1500
2000
2314
Detailed signature matches

Unintegrated signatures
-
cd09076 (L1-EN)590 - 827
-
cd09276 (Rnase_HI_R...)1,824 - 1,960
-
mobidb-lite (disord...)2,294 - 2,3141 - 60382 - 467
Residue annotation
-
putative catalytic...594N622E697Y735D737N794D821D822H
-
putative metal bin...
-
putative phosphate...
-
active site cd092761,828D1,871E1,893D1,956D
-
RNA/DNA hybrid bin...1,828DRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,829GRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,830SRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,831MRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,866SRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,867SRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,868TRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,871ERNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,893DRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,942KRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,960KRNA/DNA hybrid binding site
1,828D, 1,829G, 1,830S, 1,831M, 1,866S, 1,867S, 1,868T, 1,871E, 1,893D, 1,942K, 1,960K
CDD
cd09276 (Rnase_HI_RT_non_LTR)
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity
Cellular Component
None predicted.