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Protein

GBC45927.1

Length

453 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
43 - 357
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 50 100 150 200 250 300 350 400 453

Detailed signature matches

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

118 - 357

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

43 - 85

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

IPR000719

Protein kinase domain

SM00220 (serkin_6)

46 - 337

SMART
SM00220 (serkin_6)
PS50011 (PROTEIN_KI...)

46 - 337

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)
PF00069 (Pkinase)

121 - 337

Pfam
PF00069 (Pkinase)

IPR017441

Protein kinase, ATP binding site

PS00107 (PROTEIN_KI...)

52 - 75

PROSITE patterns
PS00107 (PROTEIN_KINASE_ATP)

IPR008271

Serine/threonine-protein kinase, active site

PS00108 (PROTEIN_KI...)

201 - 213

PROSITE patterns
PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

Coil

414 - 446

COILS
Coil (Coil)
cd14008 (STKc_LKB1_...)

52 - 337

CDD
cd14008 (STKc_LKB1_CaMKK)
mobidb-lite (disord...)

1 - 22

MobiDB Lite
mobidb-lite (disorder_prediction)

412 - 453

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

52I

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

53G

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

54H

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

55G

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

56A

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

60V

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

73A

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

75K

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

139V

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

157F

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

158E

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

159M

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

160C

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

164V

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

205D

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

207K

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

209D

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

210N

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

212L

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)

223D

ATP binding site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 205D, 207K, 209D, 210N, 212L, 223D
CDD
cd14008 (STKc_LKB1_CaMKK)
active site cd14008

52I

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

53G

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

54H

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

55G

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

56A

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

60V

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

73A

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

75K

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

139V

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

157F

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

158E

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

159M

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

160C

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

164V

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

166M

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

205D

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

207K

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

209D

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

210N

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

212L

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

223D

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

226V

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

242G

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

243S

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

244P

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

245A

active site
52I, 53G, 54H, 55G, 56A, 60V, 73A, 75K, 139V, 157F, 158E, 159M, 160C, 164V, 166M, 205D, 207K, 209D, 210N, 212L, 223D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)
polypeptide substr...

56A

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

164V

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

166M

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

205D

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

207K

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

209D

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

226V

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

242G

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

243S

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

244P

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

245A

polypeptide substrate binding site
56A, 164V, 166M, 205D, 207K, 209D, 226V, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)
activation loop (A...

222V

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

223D

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

224F

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

225G

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

226V

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

227S

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

228E

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

229M

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

230F

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

231V

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

239K

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

240S

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

241A

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

242G

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

243S

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

244P

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

245A

activation loop (A-loop)
222V, 223D, 224F, 225G, 226V, 227S, 228E, 229M, 230F, 231V, 239K, 240S, 241A, 242G, 243S, 244P, 245A
CDD
cd14008 (STKc_LKB1_CaMKK)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component