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Protein

GBC43140.1

Length

605 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
24 - 468
AMP-dependent synthetase/ligase (IPR000873)

1 100 200 300 400 500 605

Detailed signature matches

IPR000873

AMP-dependent synthetase/ligase

PF00501 (AMP-binding)

24 - 468

Pfam
PF00501 (AMP-binding)

IPR020845

AMP-binding, conserved site

PS00455 (AMP_BINDING)

173 - 184

PROSITE patterns
PS00455 (AMP_BINDING)

no IPR

Unintegrated signatures

SSF56801 (Acetyl-Co...)

21 - 282

SUPERFAMILY
SSF56801 (Acetyl-CoA synthetase-like)

323 - 601

SUPERFAMILY
SSF56801 (Acetyl-CoA synthetase-like)
cd05927 (LC-FACS_euk)

24 - 600

CDD
cd05927 (LC-FACS_euk)

Residue annotation

acyl-activating en...

173I

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

176T

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

177S

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

178G

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

179T

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

180T

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

181G

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

183P

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)

184K

acyl-activating enzyme (AAE) consensus motif
173I, 176T, 177S, 178G, 179T, 180T, 181G, 183P, 184K
CDD
cd05927 (LC-FACS_euk)
putative active si...

176T

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

222L

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

223P

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

268V

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

270R

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

271L

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

274R

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

297A

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

298F

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

359E

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

360G

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

361Y

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

362G

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

363Q

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

364T

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

446D

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

458I

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

461R

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

470Q

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

471G

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

472E

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

473Y

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)

557F

putative active site
176T, 222L, 223P, 268V, 270R, 271L, 274R, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 470Q, 471G, 472E, 473Y, 557F
CDD
cd05927 (LC-FACS_euk)
putative AMP bindi...

176T

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

297A

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

298F

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

359E

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

360G

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

361Y

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

362G

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

363Q

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

364T

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

446D

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

458I

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

461R

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

473Y

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)

580T

putative AMP binding site
176T, 297A, 298F, 359E, 360G, 361Y, 362G, 363Q, 364T, 446D, 458I, 461R, 473Y, 580T
CDD
cd05927 (LC-FACS_euk)
putative CoA bindi...

222L

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

270R

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

271L

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

274R

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

297A

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

470Q

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

471G

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

472E

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

555K

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

557F

putative CoA binding site
222L, 270R, 271L, 274R, 297A, 470Q, 471G, 472E, 555K, 557F
CDD
cd05927 (LC-FACS_euk)

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC43140.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component