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Protein

GBC42302.1

Length

366 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
166 - 366
Carbon-nitrogen hydrolase (IPR003010)

1 50 100 150 200 250 300 366

Detailed signature matches

IPR003010

Carbon-nitrogen hydrolase

PS50263 (CN_HYDROLASE)

166 - 366

PROSITE profiles
PS50263 (CN_HYDROLASE)
SSF56317 (Carbon-ni...)

184 - 364

SUPERFAMILY
SSF56317 (Carbon-nitrogen hydrolase)
PF00795 (CN_hydrolase)

217 - 351

Pfam
PF00795 (CN_hydrolase)

no IPR

Unintegrated signatures

cd07197 (nitrilase)

180 - 365

CDD
cd07197 (nitrilase)

Residue annotation

catalytic triad cd...

203E

catalytic triad
203E, 263K, 297C
CDD
cd07197 (nitrilase)

263K

catalytic triad
203E, 263K, 297C
CDD
cd07197 (nitrilase)

297C

catalytic triad
203E, 263K, 297C
CDD
cd07197 (nitrilase)
active site cd07197

203E

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

263K

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

267V

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

271E

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

297C

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

298Y

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

300F

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

301N

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)

322N

active site
203E, 263K, 267V, 271E, 297C, 298Y, 300F, 301N, 322N
CDD
cd07197 (nitrilase)
dimer interface cd...

264T

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

265H

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

266L

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

267V

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

270L

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

277G

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

278D

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

279N

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

298Y

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

300F

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

301N

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

302F

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

303P

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

304I

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

307G

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

308Q

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

326I

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

327V

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

329V

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

330P

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

331K

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

337I

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

338E

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

350G

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

351I

dimer interface
264T, 265H, 266L, 267V, 270L, 277G, 278D, 279N, 298Y, 300F, 301N, 302F, 303P, 304I, 307G, 308Q, 326I, 327V, 329V, 330P, 331K, 337I, 338E, 350G, 351I
CDD
cd07197 (nitrilase)

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process

Molecular Function

GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component