Protein

GBC41848.1

Length
1,397 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1397

Detailed signature matches

  1. Family IPR011822
    Cobalamin-dependent methionine synthase
    1. TIGR02082
    2. PIRSF000381 (Met_sy...)
  2. Domain IPR003726
    Homocysteine-binding domain
    1. PS50970 (HCY)
    2. SSF82282 (Homocyste...)
    3. PF02574 (S-methyl_t...)
  3. Domain IPR011005
    Dihydropteroate synthase-like
    1. SSF51717 (Dihydropt...)
  4. Domain IPR000489
    Pterin-binding domain
    1. PS50972 (PTERIN_BIN...)
    2. PF00809 (Pterin_bind)
  5. Domain IPR003759
    Cobalamin (vitamin B12)-binding module, cap domain
    1. PF02607 (B12-binding_2)
    2. SM01018 (B12_bindin...)
    3. SSF47644 (Methionin...)
    4. PS51337 (B12_BINDIN...)
  6. Domain IPR033706
    Methionine synthase, B12-binding domain
    1. cd02069 (methionine...)
  7. Domain IPR006158
    Cobalamin (vitamin B12)-binding domain
    1. SSF52242 (Cobalamin...)
    2. PS51332 (B12_BINDING)
    3. PF02310 (B12-binding)
  8. Domain IPR004223
    Vitamin B12-dependent methionine synthase, activation domain
    1. PF02965 (Met_synt_B12)
    2. SSF56507 (Methionin...)
    3. PS50974 (ADOMET_ACT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00740 (MeTr)

Residue annotation

  1. substrate binding ...
  2. B12 binding site c...
  3. cobalt ligand cd02...

GO term prediction

Biological Process

GO:0009086 methionine biosynthetic process
GO:0042558 pteridine-containing compound metabolic process
GO:0044237 cellular metabolic process

Molecular Function

GO:0008270 zinc ion binding
GO:0008705 methionine synthase activity
GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity
GO:0031419 cobalamin binding
GO:0046872 metal ion binding

Cellular Component

GO:0005622 intracellular