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Protein

GBC40827.1

Length

335 amino acids

Protein family membership

Ubiquitin/SUMO-activating enzyme E1 (IPR000011)

Domains and repeats

Domain
9 - 327
THIF-type NAD/FAD binding fold (IPR000594)

1 50 100 150 200 250 300 335

Detailed signature matches

IPR000011

Ubiquitin/SUMO-activating enzyme E1

PR01849 (UBIQUITINACT)

153 - 180

PRINTS
PR01849 (UBIQUITINACT)

37 - 61

PRINTS
PR01849 (UBIQUITINACT)

IPR000594

THIF-type NAD/FAD binding fold

PF00899 (ThiF)

16 - 327

Pfam
PF00899 (ThiF)
SSF69572 (Activatin...)

9 - 326

SUPERFAMILY
SSF69572 (Activating enzymes of the ubiquitin-like proteins)

no IPR

Unintegrated signatures

cd01492 (Aos1_SUMO)

13 - 326

CDD
cd01492 (Aos1_SUMO)

Residue annotation

dimer interaction ...

15L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

17D

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

18R

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

19Q

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

20I

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

21R

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

22L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

23W

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

25L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

47E

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

50K

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

51N

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

54L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

70E

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

71E

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

73L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

74G

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

75A

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

77F

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

84L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

95G

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

98H

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

99L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

158F

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

289A

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

293G

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

297Q

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

319I

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

GO term prediction

Biological Process

GO:0006464 cellular protein modification process

Molecular Function

GO:0008641 small protein activating enzyme activity

Cellular Component

None predicted.