GBC40827.1

Protein

Length

335 amino acids

Protein family membership

Ubiquitin/SUMO-activating enzyme E1 (IPR000011)

Domains and repeats

Domain
9 - 327
THIF-type NAD/FAD binding fold (IPR000594)

1 50 100 150 200 250 300 335

Detailed signature matches

IPR000011

Ubiquitin/SUMO-activating enzyme E1
1. PR01849 (UBIQUITINACT)
  
  153 - 180
  
  PRINTS
  PR01849 (UBIQUITINACT)
  
  37 - 61
  
  PRINTS
  PR01849 (UBIQUITINACT)
IPR000594

THIF-type NAD/FAD binding fold
1. PF00899 (ThiF)
  
  16 - 327
  
  Pfam
  PF00899 (ThiF)
2. SSF69572 (Activatin...)
  
  9 - 326
  
  SUPERFAMILY
  SSF69572 (Activating enzymes of the ubiquitin-like proteins)

no IPR

Unintegrated signatures

cd01492 (Aos1_SUMO)

13 - 326

CDD
cd01492 (Aos1_SUMO)

Residue annotation

dimer interaction ...

15L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

17D

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

18R

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

19Q

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

20I

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

21R

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

22L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

23W

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

25L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

47E

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

50K

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

51N

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

54L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

70E

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

71E

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

73L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

74G

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

75A

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

77F

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

84L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

95G

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

98H

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

99L

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

158F

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

289A

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

293G

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

297Q

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

319I

dimer interaction
15L, 17D, 18R, 19Q, 20I, 21R, 22L, 23W, 25L, 47E, 50K, 51N, 54L, 70E, 71E, 73L, 74G, 75A, 77F, 84L, 95G, 98H, 99L, 158F, 289A, 293G, 297Q, 319I
CDD
cd01492 (Aos1_SUMO)

GO term prediction

Biological Process

GO:0006464 cellular protein modification process

Molecular Function

GO:0008641 small protein activating enzyme activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features