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Entry type
Status
Per-residue features
Colour by
Protein
GBC39433.1
Length
1,795 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain736 - 838
- Retrotransposon gag domain (IPR005162)
926 - 961- Zinc finger, CCHC-type (IPR001878)
1,108 - 1,135- Zinc finger, CCHC-type (IPR001878)
1,187 - 1,275- Aspartic peptidase domain (IPR021109)
1,402 - 1,581- Reverse transcriptase domain (IPR000477)
1
200
400
600
800
1000
1200
1400
1600
1795
Detailed signature matches
no IPR
Unintegrated signatures
-
515 - 535
-
SSF56672 (DNA/RNA p...)1,346 - 1,780
-
cd00303 (retropepsi...)1,190 - 1,263
-
cd01647 (RT_LTR)1,405 - 1,581
-
cd09274 (RNase_HI_R...)1,675 - 1,794
-
mobidb-lite (disord...)921 - 940244 - 2651,052 - 1,101541 - 616962 - 1,012
Residue annotation
-
Catalytic residue ...1,193D
-
catalytic motif cd...
-
inhibitor binding ...1,193Dinhibitor binding site
1,193D, 1,195G, 1,197A, 1,222V, 1,223M, 1,261V
CDD
cd00303 (retropepsin_like)1,195Ginhibitor binding site
1,193D, 1,195G, 1,197A, 1,222V, 1,223M, 1,261V
CDD
cd00303 (retropepsin_like)1,197Ainhibitor binding site
1,193D, 1,195G, 1,197A, 1,222V, 1,223M, 1,261V
CDD
cd00303 (retropepsin_like)1,222Vinhibitor binding site
1,193D, 1,195G, 1,197A, 1,222V, 1,223M, 1,261V
CDD
cd00303 (retropepsin_like)1,223Minhibitor binding site
1,193D, 1,195G, 1,197A, 1,222V, 1,223M, 1,261V
CDD
cd00303 (retropepsin_like)1,261Vinhibitor binding site
1,193D, 1,195G, 1,197A, 1,222V, 1,223M, 1,261V
CDD
cd00303 (retropepsin_like) -
Active site flap c...1,222VActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like)1,223MActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like)1,224IActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like)1,228KActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like)1,229VActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like)1,230AActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like)1,231SActive site flap
1,222V, 1,223M, 1,224I, 1,228K, 1,229V, 1,230A, 1,231S
CDD
cd00303 (retropepsin_like) -
putative NTP bindi...1,468Dputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,469Lputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,470Aputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,471Sputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,472Gputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,473Fputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,502Fputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR)1,532Dputative NTP binding site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,532D
CDD
cd01647 (RT_LTR) -
putative active si...1,468Dputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,469Lputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,470Aputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,471Sputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,472Gputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,473Fputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,502Fputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,503Gputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,530Yputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,532Dputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,533Dputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,577Lputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR)1,578Gputative active site
1,468D, 1,469L, 1,470A, 1,471S, 1,472G, 1,473F, 1,502F, 1,503G, 1,530Y, 1,532D, 1,533D, 1,577L, 1,578G
CDD
cd01647 (RT_LTR) -
putative nucleic a...1,503G
-
active site cd092741,679D1,721E1,746D1,789D
-
RNA/DNA hybrid bin...1,679DRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,680ARNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,681SRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,682GRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,716PRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,717IRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,718TRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,721ERNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,746DRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,779HRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)1,793RRNA/DNA hybrid binding site
1,679D, 1,680A, 1,681S, 1,682G, 1,716P, 1,717I, 1,718T, 1,721E, 1,746D, 1,779H, 1,793R
CDD
cd09274 (RNase_HI_RT_Ty3)
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Cellular Component
None predicted.