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Entry type
Status
Per-residue features
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Protein
GBC37765.1
Length
938 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain98 - 187
- Cdc24/Scd1, N-terminal (IPR010481)
393 - 541- PH domain-like (IPR011993)
- Pleckstrin homology domain (IPR001849)
852 - 938- PB1 domain (IPR000270)
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Domain210 - 412
- Dbl homology (DH) domain (IPR000219)
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938
Detailed signature matches

Unintegrated signatures
-
378 - 407
-
PF15411 (PH_10)418 - 534
-
SSF54277 (CAD & PB1...)843 - 936
-
cd00160 (RhoGEF)217 - 389
-
cd05992 (PB1)854 - 938
-
mobidb-lite (disord...)793 - 845581 - 719
Residue annotation
-
GTPase interaction...223EGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)227TGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)339PGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)340SGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)343IGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)344KGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)346IGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)347QGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)350CGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)351KGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)354LGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)355LGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)358EGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)385AGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF)389NGTPase interaction site
223E, 227T, 339P, 340S, 343I, 344K, 346I, 347Q, 350C, 351K, 354L, 355L, 358E, 385A, 389N
CDD
cd00160 (RhoGEF) -
PB1 interaction cd...854K856K862D863I864F880R934N
-
PB1 interaction su...854K856K863I864F865V880R884K934N
-
PB1 interaction su...
-
PB1 interaction si...
-
PB1 interaction su...
GO term prediction
Biological Process
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Cellular Component
None predicted.