GBC37283.1

Protein

Length

283 amino acids

Protein family membership

Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type (IPR032259)

Domains and repeats

Domain
2 - 278
ClpP/crotonase-like domain (IPR029045)

1 50 100 150 200 250 283

Detailed signature matches

IPR032259

Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type
1. PF16113 (ECH_2)
  
  14 - 254
  
  Pfam
  PF16113 (ECH_2)
IPR029045

ClpP/crotonase-like domain
1. SSF52096 (ClpP/crot...)
  
  2 - 278
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)

no IPR

Unintegrated signatures

cd06558 (crotonase-...)

5 - 218

CDD
cd06558 (crotonase-like)

Residue annotation

substrate binding ...

24G

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

26S

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

58K

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

62T

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

63G

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

64M

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

65D

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

66L

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

125P

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

127L

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

128G

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

129G

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

152N

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

153E

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)

156V

substrate binding site
24G, 26S, 58K, 62T, 63G, 64M, 65D, 66L, 125P, 127L, 128G, 129G, 152N, 153E, 156V
CDD
cd06558 (crotonase-like)
oxyanion hole (OAH...

64M

oxyanion hole (OAH) forming residues
64M, 129G
CDD
cd06558 (crotonase-like)

129G

oxyanion hole (OAH) forming residues
64M, 129G
CDD
cd06558 (crotonase-like)
trimer interface c...

109N

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

117V

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

138D

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

139I

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

140R

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

141I

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

154V

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

155K

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

156V

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

157G

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

163I

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

165Q

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

166Y

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

167I

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

169P

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

170E

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

174F

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

175K

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

177K

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

178Q

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

180M

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

181L

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

184E

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

195G

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

198S

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

214Y

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

217M

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

218L

trimer interface
109N, 117V, 138D, 139I, 140R, 141I, 154V, 155K, 156V, 157G, 163I, 165Q, 166Y, 167I, 169P, 170E, 174F, 175K, 177K, 178Q, 180M, 181L, 184E, 195G, 198S, 214Y, 217M, 218L
CDD
cd06558 (crotonase-like)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

GBC37283.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component