Protein

GBC36196.1

Length
632 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 632

Detailed signature matches

  1. Family IPR003000
    Sirtuin family
    1. PF02146 (SIR2)
  2. Domain IPR007654
    NAD-dependent histone deacetylase Sir2, N-terminal
    1. PF04574 (DUF592)
  3. Domain IPR029035
    DHS-like NAD/FAD-binding domain
    1. SSF52467 (DHS-like ...)
  4. Domain IPR026590
    Sirtuin family, catalytic core domain
    1. PS50305 (SIRTUIN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd01408 (SIRT1)
  3. mobidb-lite (disord...)

Residue annotation

  1. NAD+ binding site ...
  2. substrate binding ...
  3. Zn binding site cd...

GO term prediction

Biological Process

GO:0006342 chromatin silencing
GO:0006355 regulation of transcription, DNA-templated
GO:0006476 protein deacetylation

Molecular Function

GO:0008270 zinc ion binding
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0051287 NAD binding
GO:0070403 NAD+ binding

Cellular Component

None predicted.