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Protein

GBC35039.1

Length

331 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
20 - 316
Tryptophan synthase beta subunit-like PLP-dependent enzyme (IPR001926)

1 50 100 150 200 250 300 331

Detailed signature matches

IPR001926

Tryptophan synthase beta subunit-like PLP-dependent enzyme

PF00291 (PALP)

207 - 296

Pfam
PF00291 (PALP)

28 - 199

Pfam
PF00291 (PALP)
SSF53686 (Tryptopha...)

20 - 316

SUPERFAMILY
SSF53686 (Tryptophan synthase beta subunit-like PLP-dependent enzymes)

IPR001216

Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site

PS00901 (CYS_SYNTHASE)

51 - 69

PROSITE patterns
PS00901 (CYS_SYNTHASE)

no IPR

Unintegrated signatures

cd01561 (CBS_like)

30 - 303

CDD
cd01561 (CBS_like)

Residue annotation

dimer interface cd...

34L

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

35I

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

36R

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

49L

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

55M

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

57P

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

99H

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

102R

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

118Q

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

119E

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

122D

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

123L

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

126M

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

127L

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

184E

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

185Q

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

259L

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

260D

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

261E

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

263G

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

264L

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

265Y

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

289K

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

299Y

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)

302Q

dimer interface
34L, 35I, 36R, 49L, 55M, 57P, 99H, 102R, 118Q, 119E, 122D, 123L, 126M, 127L, 184E, 185Q, 259L, 260D, 261E, 263G, 264L, 265Y, 289K, 299Y, 302Q
CDD
cd01561 (CBS_like)
catalytic residue ...

62K

catalytic residue
62K
CDD
cd01561 (CBS_like)
pyridoxal 5'-phosp...

62K

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

92N

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

197T

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

198G

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

199S

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

200V

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

223G

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

269S

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

295C

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

296D

pyridoxal 5'-phosphate binding site
62K, 92N, 197T, 198G, 199S, 200V, 223G, 269S, 295C, 296D
CDD
cd01561 (CBS_like)

GO term prediction

Biological Process

GO:0006535 cysteine biosynthetic process from serine

Molecular Function

None predicted.

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC35039.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component