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Entry type
Status
Per-residue features
Colour by
Protein
GBC35023.1
Length
247 amino acids
Protein family membership
- Small GTPase superfamily (IPR001806)
Domains and repeats
-
Domain34 - 206
- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- Small GTP-binding protein domain (IPR005225)
- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1
50
100
150
200
247
Detailed signature matches

Unintegrated signatures
Residue annotation
-
Rab subfamily moti...
-
G1 box cd0186040G41E42A43A44V45G46K47S
-
GTP/Mg2+ binding s...42AGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)43AGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)44VGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)45GGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)46KGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)47SGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)48SGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)58FGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)59QGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)64PGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)65TGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)91GGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)146NGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)147KGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)149DGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)188SGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)189AGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related)190KGTP/Mg2+ binding site
42A, 43A, 44V, 45G, 46K, 47S, 48S, 58F, 59Q, 64P, 65T, 91G, 146N, 147K, 149D, 188S, 189A, 190K
CDD
cd01860 (Rab5_related) -
Rab subfamily moti...48SRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)49LRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)50VRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)51LRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)52RRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)53FRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)54VRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)55NRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)56NRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)57ERab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)58FRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)59QRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)63ERab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related)64PRab subfamily motif 2 (RabSF2)
48S, 49L, 50V, 51L, 52R, 53F, 54V, 55N, 56N, 57E, 58F, 59Q, 63E, 64P
CDD
cd01860 (Rab5_related) -
Switch I region cd...58F63E64P65T66I67G68A69A70F71L
-
putative GEF inter...63Eputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)67Gputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)68Aputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)69Aputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)70Fputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)71Lputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)72Tputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)73Qputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)74Kputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)81Vputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related)83Kputative GEF interaction site
63E, 67G, 68A, 69A, 70F, 71L, 72T, 73Q, 74K, 81V, 83K
CDD
cd01860 (Rab5_related) -
G2 box cd0186065T
-
Rab family motif 1...66I67G68A69A70F
-
putative GDI inter...66Iputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)67Gputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)69Aputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)87Wputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)88Dputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)95Fputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)97Sputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)99Aputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)100Pputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related)101Mputative GDI interaction site
66I, 67G, 69A, 87W, 88D, 95F, 97S, 99A, 100P, 101M
CDD
cd01860 (Rab5_related) -
effector interacti...68A69A70F72T94R101M102Y
-
Rab family motif 2...83K84F85E86I87W
-
G3 box cd01860
-
Switch II region c...91GSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)93ESwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)94RSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)95FSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)96HSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)97SSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)98LSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)99ASwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)100PSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)101MSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)102YSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related)103YSwitch II region
91G, 93E, 94R, 95F, 96H, 97S, 98L, 99A, 100P, 101M, 102Y, 103Y
CDD
cd01860 (Rab5_related) -
Rab family motif 3...94R95F96H97S98L99A
-
Rab family motif 4...
-
Rab family motif 5...111V112V113Y114D115V116T
-
Rab subfamily moti...138N139I140V141I142A143L
-
G4 box cd01860
-
G5 box cd01860
-
Rab subfamily moti...
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Cellular Component
None predicted.