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Protein

GBC34986.1

Length

526 amino acids

Protein family membership

Peptidase M17, leucine aminopeptidase/peptidase B (IPR011356)

Domains and repeats

Domain
12 - 135
Peptidase M17, leucyl aminopeptidase, N-terminal (IPR008283)
168 - 515
Peptidase M17, leucyl aminopeptidase, C-terminal (IPR000819)

1 50 100 150 200 250 300 350 400 450 500 526

Detailed signature matches

IPR011356

Peptidase M17, leucine aminopeptidase/peptidase B

PR00481 (LAMNOPPTDASE)

305 - 326

PRINTS
PR00481 (LAMNOPPTDASE)

268 - 289

PRINTS
PR00481 (LAMNOPPTDASE)

327 - 347

PRINTS
PR00481 (LAMNOPPTDASE)

246 - 263

PRINTS
PR00481 (LAMNOPPTDASE)

356 - 371

PRINTS
PR00481 (LAMNOPPTDASE)
cd00433 (Peptidase_M17)

9 - 519

CDD
cd00433 (Peptidase_M17)

IPR008283

Peptidase M17, leucyl aminopeptidase, N-terminal

PF02789 (Peptidase_...)

12 - 135

Pfam
PF02789 (Peptidase_M17_N)

IPR000819

Peptidase M17, leucyl aminopeptidase, C-terminal

PF00883 (Peptidase_M17)

168 - 515

Pfam
PF00883 (Peptidase_M17)
PS00631 (CYTOSOL_AP)

331 - 338

PROSITE patterns
PS00631 (CYTOSOL_AP)

no IPR

Unintegrated signatures

SSF52949 (Macro dom...)

9 - 148

SUPERFAMILY
SSF52949 (Macro domain-like)
SSF53187 (Zn-depend...)

482 - 521

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

164 - 444

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

Residue annotation

interface (dimer o...

43C

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

44A

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

57Y

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

68Q

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

86E

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

175N

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

177P

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

178A

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

179N

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

224G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

226D

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

255F

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

261S

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

266A

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

269S

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

272K

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

273I

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

305E

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

307L

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

308P

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

309S

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

310G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

312A

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

314K

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

315P

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

316G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

317D

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

318V

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

324G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

326S

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

330D

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

367G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

368V

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

369A

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

370L

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

371G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

375Y

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

401W

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

402R

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

404P

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

409Y

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

411K

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

412S

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

418V

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

420D

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

430G

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

431S

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

433C

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)

505K

interface (dimer of trimers)
43C, 44A, 57Y, 68Q, 86E, 175N, 177P, 178A, 179N, 224G, 226D, 255F, 261S, 266A, 269S, 272K, 273I, 305E, 307L, 308P, 309S, 310G, 312A, 314K, 315P, 316G, 317D, 318V, 324G, 326S, 330D, 367G, 368V, 369A, 370L, 371G, 375Y, 401W, 402R, 404P, 409Y, 411K, 412S, 418V, 420D, 430G, 431S, 433C, 505K
CDD
cd00433 (Peptidase_M17)
Zn-binding sites c...

251K

Zn-binding sites
251K, 256D, 274D, 333D, 335E
CDD
cd00433 (Peptidase_M17)

256D

Zn-binding sites
251K, 256D, 274D, 333D, 335E
CDD
cd00433 (Peptidase_M17)

274D

Zn-binding sites
251K, 256D, 274D, 333D, 335E
CDD
cd00433 (Peptidase_M17)

333D

Zn-binding sites
251K, 256D, 274D, 333D, 335E
CDD
cd00433 (Peptidase_M17)

335E

Zn-binding sites
251K, 256D, 274D, 333D, 335E
CDD
cd00433 (Peptidase_M17)
Substrate-binding/...

251K

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

256D

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

263K

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

274D

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

333D

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

335E

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

337R

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

362L

Substrate-binding/catalytic site
251K, 256D, 263K, 274D, 333D, 335E, 337R, 362L
CDD
cd00433 (Peptidase_M17)

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0019538 protein metabolic process

Molecular Function

GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding

Cellular Component

GO:0005622 intracellular
GO:0005737 cytoplasm