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Protein

GBC34939.1

Length

566 amino acids

Protein family membership

Peptidase M17, leucine aminopeptidase/peptidase B (IPR011356)
- Peptidase M17, leucine aminopeptidase (IPR023042)

Domains and repeats

Domain
51 - 173
Peptidase M17, leucyl aminopeptidase, N-terminal (IPR008283)
208 - 555
Peptidase M17, leucyl aminopeptidase, C-terminal (IPR000819)

1 100 200 300 400 500 566

Detailed signature matches

IPR011356

Peptidase M17, leucine aminopeptidase/peptidase B

PR00481 (LAMNOPPTDASE)

286 - 303

PRINTS
PR00481 (LAMNOPPTDASE)

308 - 329

PRINTS
PR00481 (LAMNOPPTDASE)

367 - 387

PRINTS
PR00481 (LAMNOPPTDASE)

396 - 411

PRINTS
PR00481 (LAMNOPPTDASE)

345 - 366

PRINTS
PR00481 (LAMNOPPTDASE)
cd00433 (Peptidase_M17)

48 - 557

CDD
cd00433 (Peptidase_M17)

IPR023042

Peptidase M17, leucine aminopeptidase

MF_00181 (Cytosol_p...)

35 - 564

HAMAP
MF_00181 (Cytosol_peptidase_M17)

IPR008283

Peptidase M17, leucyl aminopeptidase, N-terminal

PF02789 (Peptidase_...)

51 - 173

Pfam
PF02789 (Peptidase_M17_N)

IPR000819

Peptidase M17, leucyl aminopeptidase, C-terminal

PF00883 (Peptidase_M17)

208 - 555

Pfam
PF00883 (Peptidase_M17)
PS00631 (CYTOSOL_AP)

371 - 378

PROSITE patterns
PS00631 (CYTOSOL_AP)

no IPR

Unintegrated signatures

SSF52949 (Macro dom...)

48 - 189

SUPERFAMILY
SSF52949 (Macro domain-like)
SSF53187 (Zn-depend...)

522 - 560

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

204 - 484

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

Residue annotation

interface (dimer o...

82C

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

83A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

96Y

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

107K

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

122E

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

215N

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

217P

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

218A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

219N

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

264G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

266N

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

295F

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

301S

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

306A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

309S

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

312K

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

313I

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

345E

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

347L

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

348P

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

349S

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

350G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

352A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

354K

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

355P

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

356G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

357D

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

358V

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

364G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

366S

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

370D

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

407A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

408V

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

409A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

410L

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

411G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

415Y

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

441W

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

442R

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

444P

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

449Y

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

451K

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

452A

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

458V

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

460D

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

470G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

471G

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

473C

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)

545K

interface (dimer of trimers)
82C, 83A, 96Y, 107K, 122E, 215N, 217P, 218A, 219N, 264G, 266N, 295F, 301S, 306A, 309S, 312K, 313I, 345E, 347L, 348P, 349S, 350G, 352A, 354K, 355P, 356G, 357D, 358V, 364G, 366S, 370D, 407A, 408V, 409A, 410L, 411G, 415Y, 441W, 442R, 444P, 449Y, 451K, 452A, 458V, 460D, 470G, 471G, 473C, 545K
CDD
cd00433 (Peptidase_M17)
Zn-binding sites c...

291K

Zn-binding sites
291K, 296D, 314D, 373D, 375E
CDD
cd00433 (Peptidase_M17)

296D

Zn-binding sites
291K, 296D, 314D, 373D, 375E
CDD
cd00433 (Peptidase_M17)

314D

Zn-binding sites
291K, 296D, 314D, 373D, 375E
CDD
cd00433 (Peptidase_M17)

373D

Zn-binding sites
291K, 296D, 314D, 373D, 375E
CDD
cd00433 (Peptidase_M17)

375E

Zn-binding sites
291K, 296D, 314D, 373D, 375E
CDD
cd00433 (Peptidase_M17)
Substrate-binding/...

291K

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

296D

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

303K

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

314D

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

373D

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

375E

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

377R

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

402L

Substrate-binding/catalytic site
291K, 296D, 303K, 314D, 373D, 375E, 377R, 402L
CDD
cd00433 (Peptidase_M17)

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0019538 protein metabolic process

Molecular Function

GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding

Cellular Component

GO:0005622 intracellular
GO:0005737 cytoplasm