GBC34503.1

Protein

Length

396 amino acids

Protein family membership

Enolase (IPR000941)

Domains and repeats

Domain
3 - 139
Enolase N-terminal domain-like (IPR029017)
Enolase, N-terminal (IPR020811)
143 - 393
Enolase C-terminal domain-like (IPR029065)
Enolase, C-terminal TIM barrel domain (IPR020810)

1 50 100 150 200 250 300 350 396

Detailed signature matches

IPR000941

Enolase
1. MF_00318 (Enolase)
  
  1 - 379
  
  HAMAP
  MF_00318 (Enolase)
2. cd03313 (enolase)
  
  5 - 378
  
  CDD
  cd03313 (enolase)
3. PR00148 (ENOLASE)
  
  35 - 49
  
  PRINTS
  PR00148 (ENOLASE)
  
  279 - 290
  
  PRINTS
  PR00148 (ENOLASE)
  
  302 - 316
  
  PRINTS
  PR00148 (ENOLASE)
  
  331 - 348
  
  PRINTS
  PR00148 (ENOLASE)
IPR029017

Enolase N-terminal domain-like
1. SSF54826 (Enolase N...)
  
  3 - 139
  
  SUPERFAMILY
  SSF54826 (Enolase N-terminal domain-like)
IPR020811

Enolase, N-terminal
1. SM01193 (Enolase_N_3)
  
  3 - 134
  
  SMART
  SM01193 (Enolase_N_3)
2. PF03952 (Enolase_N)
  
  3 - 134
  
  Pfam
  PF03952 (Enolase_N)
IPR029065

Enolase C-terminal domain-like
1. SSF51604 (Enolase C...)
  
  144 - 391
  
  SUPERFAMILY
  SSF51604 (Enolase C-terminal domain-like)
IPR020810

Enolase, C-terminal TIM barrel domain
1. SM01192 (Enolase_C_3)
  
  143 - 393
  
  SMART
  SM01192 (Enolase_C_3)
2. PF00113 (Enolase_C)
  
  244 - 392
  
  Pfam
  PF00113 (Enolase_C)
  
  144 - 243
  
  Pfam
  PF00113 (Enolase_C)
IPR020809

Enolase, conserved site
1. PS00164 (ENOLASE)
  
  302 - 315
  
  PROSITE patterns
  PS00164 (ENOLASE)

Residue annotation

dimer interface cd...

7H

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

9R

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

10Q

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

11I

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

12F

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

13D

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

14S

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

15R

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

16G

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

17N

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

21E

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

32R

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

160A

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

161G

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

162N

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

183M

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

184K

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

187S

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

188E

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

191H

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

192T

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

207N

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

208V

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

215A

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

217N

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

337E

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

338T

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

339E

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

362R

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

363S

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

364E

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

366L

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

367A

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

370N

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

373L

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

374R

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)

377E

dimer interface
7H, 9R, 10Q, 11I, 12F, 13D, 14S, 15R, 16G, 17N, 21E, 32R, 160A, 161G, 162N, 183M, 184K, 187S, 188E, 191H, 192T, 207N, 208V, 215A, 217N, 337E, 338T, 339E, 362R, 363S, 364E, 366L, 367A, 370N, 373L, 374R, 377E
CDD
cd03313 (enolase)
metal binding site...

40S

metal binding site
40S, 255E, 280D
CDD
cd03313 (enolase)

255E

metal binding site
40S, 255E, 280D
CDD
cd03313 (enolase)

280D

metal binding site
40S, 255E, 280D
CDD
cd03313 (enolase)
substrate binding ...

159H

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

211E

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

305K

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

333H

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

334R

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

335S

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

356K

substrate binding pocket
159H, 211E, 305K, 333H, 334R, 335S, 356K
CDD
cd03313 (enolase)

GO term prediction

Biological Process

GO:0006096 glycolytic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity

Cellular Component

GO:0000015 phosphopyruvate hydratase complex

Filter view on

Entry type

Status

Per-residue features