GBC34495.1

Protein

Length

492 amino acids

Protein family membership

Isocitrate lyase (IPR006254)

Domains and repeats

Domain
6 - 485
Pyruvate/Phosphoenolpyruvate kinase-like domain (IPR015813)

1 50 100 150 200 250 300 350 400 450 492

Detailed signature matches

IPR006254

Isocitrate lyase
1. TIGR01346
  
  18 - 449
  
  TIGRFAMs
  TIGR01346 (TIGR01346)
2. PF00463 (ICL)
  
  450 - 480
  
  Pfam
  PF00463 (ICL)
  
  17 - 449
  
  Pfam
  PF00463 (ICL)
IPR015813

Pyruvate/Phosphoenolpyruvate kinase-like domain
1. SSF51621 (Phosphoen...)
  
  6 - 485
  
  SUPERFAMILY
  SSF51621 (Phosphoenolpyruvate/pyruvate domain)
IPR018523

Isocitrate lyase/phosphorylmutase, conserved site
1. PS00161 (ISOCITRATE...)
  
  207 - 212
  
  PROSITE patterns
  PS00161 (ISOCITRATE_LYASE)

no IPR

Unintegrated signatures

cd00377 (ICL_PEPM)

65 - 253

CDD
cd00377 (ICL_PEPM)

Residue annotation

tetramer interface...

67K

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

74T

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

77H

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

78T

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

79F

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

80G

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

82L

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

83D

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

84P

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

85I

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

86Q

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

88A

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

89Q

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

92K

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

93Y

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

94L

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

95E

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

102W

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

106S

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

107T

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

115G

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

116P

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

119A

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

120D

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

121Y

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

122P

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

124D

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

125T

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

128N

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

129K

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

131E

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

132H

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

135M

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

136A

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

177G

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

183L

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

184K

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

188M

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

191E

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

221S

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

222E

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

225N

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

228I

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

229A

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)

232V

tetramer interface
67K, 74T, 77H, 78T, 79F, 80G, 82L, 83D, 84P, 85I, 86Q, 88A, 89Q, 92K, 93Y, 94L, 95E, 102W, 106S, 107T, 115G, 116P, 119A, 120D, 121Y, 122P, 124D, 125T, 128N, 129K, 131E, 132H, 135M, 136A, 177G, 183L, 184K, 188M, 191E, 221S, 222E, 225N, 228I, 229A, 232V
CDD
cd00377 (ICL_PEPM)
active site cd00377

98Y

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

100S

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

101G

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

102W

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

117D

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

171D

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

173D

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

200E

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)

246R

active site
98Y, 100S, 101G, 102W, 117D, 171D, 173D, 200E, 246R
CDD
cd00377 (ICL_PEPM)
Mg2+/Mn2+ binding ...

117D

Mg2+/Mn2+ binding site
117D, 171D, 173D, 200E
CDD
cd00377 (ICL_PEPM)

171D

Mg2+/Mn2+ binding site
117D, 171D, 173D, 200E
CDD
cd00377 (ICL_PEPM)

173D

Mg2+/Mn2+ binding site
117D, 171D, 173D, 200E
CDD
cd00377 (ICL_PEPM)

200E

Mg2+/Mn2+ binding site
117D, 171D, 173D, 200E
CDD
cd00377 (ICL_PEPM)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0019752 carboxylic acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004451 isocitrate lyase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features