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Entry type
Status
Per-residue features
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Protein
GBC34258.1
Length
764 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain77 - 186
- Aspartic peptidase domain (IPR021109)
- Retroviral aspartyl protease (IPR013242)
370 - 549- Reverse transcriptase domain (IPR000477)
- Aspartic peptidase domain (IPR021109)
1
100
200
300
400
500
600
700
764
Detailed signature matches
no IPR
Unintegrated signatures
-
SSF56672 (DNA/RNA p...)314 - 745
-
cd00303 (retropepsi...)93 - 170
-
cd01647 (RT_LTR)373 - 549
-
cd09274 (RNase_HI_R...)643 - 762
-
mobidb-lite (disord...)206 - 256
Residue annotation
-
Catalytic residue ...94D
-
catalytic motif cd...
-
inhibitor binding ...94D96G98A122M123I124N163I
-
Active site flap c...122M123I124N125V129R130R131R132P
-
putative NTP bindi...436D437L438A439S440G441F470F500D
-
putative active si...436Dputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)437Lputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)438Aputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)439Sputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)440Gputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)441Fputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)470Fputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)471Gputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)498Yputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)500Dputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)501Dputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)545Lputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR)546Gputative active site
436D, 437L, 438A, 439S, 440G, 441F, 470F, 471G, 498Y, 500D, 501D, 545L, 546G
CDD
cd01647 (RT_LTR) -
putative nucleic a...471G
-
active site cd09274
-
RNA/DNA hybrid bin...647DRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)648ARNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)649SRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)650TRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)684GRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)685VRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)686TRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)689ERNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)714DRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)747DRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)761RRNA/DNA hybrid binding site
647D, 648A, 649S, 650T, 684G, 685V, 686T, 689E, 714D, 747D, 761R
CDD
cd09274 (RNase_HI_RT_Ty3)
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.