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Protein

GBC33830.1

Length

1,516 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
19 - 281
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
Serine-threonine/tyrosine-protein kinase, catalytic domain (IPR001245)
1,228 - 1,516
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1400 1516

Detailed signature matches

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

1,228 - 1,516

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

19 - 281

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

IPR000719

Protein kinase domain

PS50011 (PROTEIN_KI...)

25 - 277

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)

1,236 - 1,514

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)
PF00069 (Pkinase)

1,246 - 1,514

Pfam
PF00069 (Pkinase)

IPR001245

Serine-threonine/tyrosine-protein kinase, catalytic domain

PF07714 (Pkinase_Tyr)

36 - 273

Pfam
PF07714 (Pkinase_Tyr)

no IPR

Unintegrated signatures

cd00180 (PKc)

1,249 - 1,512

CDD
cd00180 (PKc)

Residue annotation

ATP binding site c...

1,250V

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,263V

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,265K

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,289V

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,308T

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,309R

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,310Y

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,311F

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,314S

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,352D

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,354N

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,356S

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,357N

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,359I

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)

1,372D

ATP binding site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D
CDD
cd00180 (PKc)
active site cd00180

1,250V

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,263V

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,265K

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,289V

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,308T

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,309R

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,310Y

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,311F

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,314S

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,316D

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,352D

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,354N

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,356S

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,357N

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,359I

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,372D

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)

1,375Y

active site
1,250V, 1,263V, 1,265K, 1,289V, 1,308T, 1,309R, 1,310Y, 1,311F, 1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,357N, 1,359I, 1,372D, 1,375Y
CDD
cd00180 (PKc)
polypeptide substr...

1,314S

polypeptide substrate binding site
1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,375Y
CDD
cd00180 (PKc)

1,316D

polypeptide substrate binding site
1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,375Y
CDD
cd00180 (PKc)

1,352D

polypeptide substrate binding site
1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,375Y
CDD
cd00180 (PKc)

1,354N

polypeptide substrate binding site
1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,375Y
CDD
cd00180 (PKc)

1,356S

polypeptide substrate binding site
1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,375Y
CDD
cd00180 (PKc)

1,375Y

polypeptide substrate binding site
1,314S, 1,316D, 1,352D, 1,354N, 1,356S, 1,375Y
CDD
cd00180 (PKc)
activation loop (A...

1,371C

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

1,372D

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

1,373F

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

1,374E

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

1,375Y

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

1,376S

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

1,377K

activation loop (A-loop)
1,371C, 1,372D, 1,373F, 1,374E, 1,375Y, 1,376S, 1,377K
CDD
cd00180 (PKc)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component