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Protein

GBC33829.1

Length

1,488 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
19 - 253
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
Serine-threonine/tyrosine-protein kinase, catalytic domain (IPR001245)
1,200 - 1,488
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1488

Detailed signature matches

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

19 - 253

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

1,200 - 1,488

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

IPR000719

Protein kinase domain

PS50011 (PROTEIN_KI...)

25 - 249

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)

1,208 - 1,486

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)
PF00069 (Pkinase)

1,218 - 1,486

Pfam
PF00069 (Pkinase)

IPR001245

Serine-threonine/tyrosine-protein kinase, catalytic domain

PF07714 (Pkinase_Tyr)

36 - 144

Pfam
PF07714 (Pkinase_Tyr)

150 - 245

Pfam
PF07714 (Pkinase_Tyr)

no IPR

Unintegrated signatures

cd00180 (PKc)

1,221 - 1,484

CDD
cd00180 (PKc)

Residue annotation

ATP binding site c...

1,222V

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,235V

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,237K

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,261V

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,280T

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,281R

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,282Y

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,283F

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,286S

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,324D

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,326N

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,328S

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,329N

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,331I

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)

1,344D

ATP binding site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D
CDD
cd00180 (PKc)
active site cd00180

1,222V

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,235V

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,237K

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,261V

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,280T

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,281R

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,282Y

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,283F

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,286S

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,288D

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,324D

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,326N

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,328S

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,329N

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,331I

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,344D

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)

1,347Y

active site
1,222V, 1,235V, 1,237K, 1,261V, 1,280T, 1,281R, 1,282Y, 1,283F, 1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,329N, 1,331I, 1,344D, 1,347Y
CDD
cd00180 (PKc)
polypeptide substr...

1,286S

polypeptide substrate binding site
1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,347Y
CDD
cd00180 (PKc)

1,288D

polypeptide substrate binding site
1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,347Y
CDD
cd00180 (PKc)

1,324D

polypeptide substrate binding site
1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,347Y
CDD
cd00180 (PKc)

1,326N

polypeptide substrate binding site
1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,347Y
CDD
cd00180 (PKc)

1,328S

polypeptide substrate binding site
1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,347Y
CDD
cd00180 (PKc)

1,347Y

polypeptide substrate binding site
1,286S, 1,288D, 1,324D, 1,326N, 1,328S, 1,347Y
CDD
cd00180 (PKc)
activation loop (A...

1,343C

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

1,344D

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

1,345F

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

1,346E

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

1,347Y

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

1,348S

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

1,349K

activation loop (A-loop)
1,343C, 1,344D, 1,345F, 1,346E, 1,347Y, 1,348S, 1,349K
CDD
cd00180 (PKc)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component