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Entry type
Status
Per-residue features
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Protein
GBC33665.1
Length
869 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain2 - 82
- Peptidase A2A, retrovirus, catalytic (IPR001995)
168 - 374- Reverse transcriptase domain (IPR000477)
596 - 865
1
100
200
300
400
500
600
700
800
869
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
Catalytic residue ...7D
-
catalytic motif cd...
-
inhibitor binding ...7D9G11G35L36T37I
-
Active site flap c...35L36T37I38A42S43I44A45L
-
putative NTP bindi...261D262L263A264A265G266Y295F325D
-
putative active si...261Dputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)262Lputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)263Aputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)264Aputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)265Gputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)266Yputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)295Fputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)296Gputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)323Yputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)325Dputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)326Dputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)370Lputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR)371Gputative active site
261D, 262L, 263A, 264A, 265G, 266Y, 295F, 296G, 323Y, 325D, 326D, 370L, 371G
CDD
cd01647 (RT_LTR) -
putative nucleic a...296G
-
active site cd09274
-
RNA/DNA hybrid bin...472DRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)473GRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)474SRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)475KRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)509PRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)510PRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)511TRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)514ERNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)539DRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)572HRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)586RRNA/DNA hybrid binding site
472D, 473G, 474S, 475K, 509P, 510P, 511T, 514E, 539D, 572H, 586R
CDD
cd09274 (RNase_HI_RT_Ty3)
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Cellular Component
None predicted.