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Entry type
Status
Per-residue features
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Protein
GBC33199.1
Length
1,870 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain134 - 376
- Endonuclease/exonuclease/phosphatase (IPR005135)
621 - 916- Reverse transcriptase domain (IPR000477)
1,375 - 1,520- Ribonuclease H-like domain (IPR012337)
- Ribonuclease H domain (IPR002156)
1
200
400
600
800
1000
1200
1400
1600
1870
Detailed signature matches
no IPR
Unintegrated signatures
-
cd09076 (L1-EN)137 - 374
-
cd09276 (Rnase_HI_R...)1,380 - 1,516
-
mobidb-lite (disord...)1 - 901,850 - 1,870
Residue annotation
-
putative catalytic...141N169E244Y282D284N341D368D369H
-
putative metal bin...
-
putative phosphate...
-
active site cd092761,384D1,427E1,449D1,512D
-
RNA/DNA hybrid bin...1,384DRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,385GRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,386SRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,387MRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,422SRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,423SRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,424TRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,427ERNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,449DRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,498KRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)1,516KRNA/DNA hybrid binding site
1,384D, 1,385G, 1,386S, 1,387M, 1,422S, 1,423S, 1,424T, 1,427E, 1,449D, 1,498K, 1,516K
CDD
cd09276 (Rnase_HI_RT_non_LTR)
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity
Cellular Component
None predicted.