GBC33178.1

Protein

Length

3,209 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1,157 - 1,243
Ubiquitin-related domain (IPR029071)
Ubiquitin domain (IPR000626)
1,327 - 1,677
Armadillo-type fold (IPR016024)
1,708 - 2,059
Ubiquitin specific protease domain (IPR028889)
Peptidase C19, ubiquitin carboxyl-terminal hydrolase (IPR001394)

1 500 1000 1500 2000 2500 3209

Detailed signature matches

IPR029071

Ubiquitin-related domain
1. SSF54236 (Ubiquitin...)
  
  1,157 - 1,243
  
  SUPERFAMILY
  SSF54236 (Ubiquitin-like)
IPR000626

Ubiquitin domain
1. PS50053 (UBIQUITIN_2)
  
  1,165 - 1,241
  
  PROSITE profiles
  PS50053 (UBIQUITIN_2)
2. PF00240 (ubiquitin)
  
  1,175 - 1,241
  
  Pfam
  PF00240 (ubiquitin)
3. SM00213 (ubq_7)
  
  1,165 - 1,241
  
  SMART
  SM00213 (ubq_7)
IPR016024

Armadillo-type fold
1. SSF48371 (ARM repeat)
  
  1,327 - 1,677
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
IPR028889

Ubiquitin specific protease domain
1. PS50235 (USP_3)
  
  1,708 - 2,059
  
  PROSITE profiles
  PS50235 (USP_3)
IPR001394

Peptidase C19, ubiquitin carboxyl-terminal hydrolase
1. PF00443 (UCH)
  
  1,708 - 2,056
  
  Pfam
  PF00443 (UCH)
IPR018200

Ubiquitin specific protease, conserved site
1. PS00973 (USP_2)
  
  1,963 - 1,980
  
  PROSITE patterns
  PS00973 (USP_2)
2. PS00972 (USP_1)
  
  1,709 - 1,724
  
  PROSITE patterns
  PS00972 (USP_1)

no IPR

Unintegrated signatures

Coil

46 - 66

COILS
Coil (Coil)
SSF54001 (Cysteine ...)

1,703 - 2,090

SUPERFAMILY
SSF54001 (Cysteine proteinases)
cd01769 (UBL)

1,178 - 1,241

CDD
cd01769 (UBL)
cd02659 (peptidase_...)

1,706 - 2,059

CDD
cd02659 (peptidase_C19C)
mobidb-lite (disord...)

1 - 205

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Ubq - UCH interact...

1,205G

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,207I

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,208R

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,235S

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,237M

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,239M

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,240K

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,241R

Ubq - UCH interaction site
1,205G, 1,207I, 1,208R, 1,235S, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)
Ubq - E2 interacti...

1,206M

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,208R

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,210I

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,213G

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,214K

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,215E

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,237M

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,239M

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,240K

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)

1,241R

Ubq - E2 interaction site
1,206M, 1,208R, 1,210I, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,240K, 1,241R
CDD
cd01769 (UBL)
Ubq - CUE interact...

1,210I

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,212S

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,213G

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,214K

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,215E

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,237M

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,239M

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)

1,241R

Ubq - CUE interaction site
1,210I, 1,212S, 1,213G, 1,214K, 1,215E, 1,237M, 1,239M, 1,241R
CDD
cd01769 (UBL)
Active Site cd02659

1,712N

Active Site
1,712N, 1,717C, 1,979H, 2,008D
CDD
cd02659 (peptidase_C19C)

1,717C

Active Site
1,712N, 1,717C, 1,979H, 2,008D
CDD
cd02659 (peptidase_C19C)

1,979H

Active Site
1,712N, 1,717C, 1,979H, 2,008D
CDD
cd02659 (peptidase_C19C)

2,008D

Active Site
1,712N, 1,717C, 1,979H, 2,008D
CDD
cd02659 (peptidase_C19C)

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0005488 binding
GO:0005515 protein binding
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component