GBC33088.1

Protein

Length

307 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Domains and repeats

Domain
59 - 304
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 307

Detailed signature matches

IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00080 (SDRFAMILY)
  
  140 - 151
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  192 - 200
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  212 - 231
  
  PRINTS
  PR00080 (SDRFAMILY)
2. PR00081 (GDHRDH)
  
  62 - 79
  
  PRINTS
  PR00081 (GDHRDH)
  
  186 - 202
  
  PRINTS
  PR00081 (GDHRDH)
  
  267 - 287
  
  PRINTS
  PR00081 (GDHRDH)
  
  233 - 250
  
  PRINTS
  PR00081 (GDHRDH)
  
  140 - 151
  
  PRINTS
  PR00081 (GDHRDH)
  
  212 - 231
  
  PRINTS
  PR00081 (GDHRDH)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  59 - 304
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR020904

Short-chain dehydrogenase/reductase, conserved site
1. PS00061 (ADH_SHORT)
  
  199 - 227
  
  PROSITE patterns
  PS00061 (ADH_SHORT)

no IPR

Unintegrated signatures

PF13561 (adh_short_C2)

70 - 302

Pfam
PF13561 (adh_short_C2)
cd05355 (SDR_c1)

26 - 306

CDD
cd05355 (SDR_c1)
mobidb-lite (disord...)

1 - 27

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

NAD binding site c...

26P

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

67G

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

69D

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

70S

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

71G

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

72I

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

92Y

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

93L

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

95R

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

120K

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

121D

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

122V

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

148N

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

149A

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

150S

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

151E

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

172T

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

177M

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

197T

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

198T

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

199S

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

212Y

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

216K

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

242P

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

243G

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

244P

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

245I

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

247T

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

248P

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

249L

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

250I

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)

262F

NAD binding site
26P, 67G, 69D, 70S, 71G, 72I, 92Y, 93L, 95R, 120K, 121D, 122V, 148N, 149A, 150S, 151E, 172T, 177M, 197T, 198T, 199S, 212Y, 216K, 242P, 243G, 244P, 245I, 247T, 248P, 249L, 250I, 262F
CDD
cd05355 (SDR_c1)
metal binding site...

69D

metal binding site
69D, 70S, 95R
CDD
cd05355 (SDR_c1)

70S

metal binding site
69D, 70S, 95R
CDD
cd05355 (SDR_c1)

95R

metal binding site
69D, 70S, 95R
CDD
cd05355 (SDR_c1)
active site cd05355

173N

active site
173N, 199S, 212Y, 216K
CDD
cd05355 (SDR_c1)

199S

active site
173N, 199S, 212Y, 216K
CDD
cd05355 (SDR_c1)

212Y

active site
173N, 199S, 212Y, 216K
CDD
cd05355 (SDR_c1)

216K

active site
173N, 199S, 212Y, 216K
CDD
cd05355 (SDR_c1)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

GBC33088.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component