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Entry type
Status
Per-residue features
Colour by
Protein
GBC30382.1
Length
2,474 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain18 - 145
- Protein argonaute, N-terminal (IPR032474)
199 - 356- PAZ domain (IPR003100)
832 - 961- Protein argonaute, N-terminal (IPR032474)
1,015 - 1,174- PAZ domain (IPR003100)
1,661 - 1,793- Protein argonaute, N-terminal (IPR032474)
1,847 - 2,003- PAZ domain (IPR003100)
-
Domain154 - 204
- Argonaute, linker 1 domain (IPR014811)
344 - 388- Argonaute linker 2 domain (IPR032472)
398 - 476- Protein argonaute, Mid domain (IPR032473)
483 - 797- Ribonuclease H-like domain (IPR012337)
- Piwi domain (IPR003165)
970 - 1,020- Argonaute, linker 1 domain (IPR014811)
1,161 - 1,206- Argonaute linker 2 domain (IPR032472)
1,217 - 1,294- Protein argonaute, Mid domain (IPR032473)
1,301 - 1,615- Ribonuclease H-like domain (IPR012337)
- Piwi domain (IPR003165)
1,802 - 1,852- Argonaute, linker 1 domain (IPR014811)
1,990 - 2,035- Argonaute linker 2 domain (IPR032472)
2,046 - 2,123- Protein argonaute, Mid domain (IPR032473)
2,130 - 2,445- Ribonuclease H-like domain (IPR012337)
- Piwi domain (IPR003165)
1
500
1000
1500
2000
2474
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
nucleic acid-bindi...256Fnucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like)271Fnucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like)280Vnucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like)284Fnucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like)302Inucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like)306Tnucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like)308Lnucleic acid-binding interface
256F, 271F, 280V, 284F, 302I, 306T, 308L
CDD
cd02846 (PAZ_argonaute_like) -
5' RNA guide stran...504Y5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)508K5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)520Q5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)521C5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)522V5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)523Q5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)526H5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)534Y5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)537N5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)541K5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like)545K5' RNA guide strand anchoring site
504Y, 508K, 520Q, 521C, 522V, 523Q, 526H, 534Y, 537N, 541K, 545K
CDD
cd04657 (Piwi_ago-like) -
active site cd04657
-
nucleic acid-bindi...1,073Fnucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like)1,088Fnucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like)1,097Inucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like)1,101Fnucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like)1,119Inucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like)1,123Tnucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like)1,125Lnucleic acid-binding interface
1,073F, 1,088F, 1,097I, 1,101F, 1,119I, 1,123T, 1,125L
CDD
cd02846 (PAZ_argonaute_like) -
5' RNA guide stran...1,322Y5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,326K5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,338Q5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,339C5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,340V5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,341Q5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,344H5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,352Y5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,355N5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,359K5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like)1,363K5' RNA guide strand anchoring site
1,322Y, 1,326K, 1,338Q, 1,339C, 1,340V, 1,341Q, 1,344H, 1,352Y, 1,355N, 1,359K, 1,363K
CDD
cd04657 (Piwi_ago-like) -
active site cd046571,390S1,392T1,464D1,601H
-
nucleic acid-bindi...1,902Fnucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like)1,917Fnucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like)1,926Inucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like)1,930Fnucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like)1,948Vnucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like)1,952Tnucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like)1,954Lnucleic acid-binding interface
1,902F, 1,917F, 1,926I, 1,930F, 1,948V, 1,952T, 1,954L
CDD
cd02846 (PAZ_argonaute_like) -
5' RNA guide stran...2,151Y5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,155K5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,167Q5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,168C5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,169I5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,170Q5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,173H5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,181Y5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,184N5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,188K5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like)2,192K5' RNA guide strand anchoring site
2,151Y, 2,155K, 2,167Q, 2,168C, 2,169I, 2,170Q, 2,173H, 2,181Y, 2,184N, 2,188K, 2,192K
CDD
cd04657 (Piwi_ago-like) -
active site cd046572,219S2,221I2,293D2,431R
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003676 nucleic acid binding
GO:0005515 protein binding
Cellular Component
None predicted.