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Entry type
Status
Per-residue features
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Protein
GBC28203.1
Length
5,455 amino acids
Protein family membership
- Midasin (IPR012099)
Domains and repeats
-
Domain341 - 623
- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- AAA+ ATPase domain (IPR003593)
672 - 1,028- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- AAA+ ATPase domain (IPR003593)
1,101 - 1,335- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- AAA+ ATPase domain (IPR003593)
1,401 - 1,700- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- AAA+ ATPase domain (IPR003593)
1,814 - 2,074- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- AAA+ ATPase domain (IPR003593)
2,112 - 2,1852,308 - 2,4175,245 - 5,443- von Willebrand factor, type A (IPR002035)
- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
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Domain365 - 486
- ATPase, dynein-related, AAA domain (IPR011704)
700 - 761- ATPase, dynein-related, AAA domain (IPR011704)
862 - 949- ATPase, dynein-related, AAA domain (IPR011704)
1,131 - 1,267- ATPase, dynein-related, AAA domain (IPR011704)
1,424 - 1,503- ATPase, dynein-related, AAA domain (IPR011704)
1,531 - 1,636- ATPase, dynein-related, AAA domain (IPR011704)
1,825 - 1,963- ATPase, dynein-related, AAA domain (IPR011704)
2,305 - 2,387- ATPase, dynein-related, AAA domain (IPR011704)
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5455
Detailed signature matches
-
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PIRSF010340 (Midasin)62 - 5,454
-
-
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SSF52540 (P-loop co...)1,814 - 2,0741,101 - 1,335863 - 1,028672 - 7482,308 - 2,4172,112 - 2,1851,401 - 1,4711,549 - 1,700341 - 623
-
no IPR
Unintegrated signatures
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cd00009 (AAA)
-
cd01460 (vWA_midasin)5,185 - 5,451
-
mobidb-lite (disord...)4,560 - 4,7564,779 - 4,998811 - 832
Residue annotation
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Walker A motif cd0...705G706E707T708G709T710G711K712T
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ATP binding site c...706E707T708G709T710G711K712T713T
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Walker B motif cd0...770I
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Walker A motif cd0...1,136G1,137H1,138T1,139S1,140A1,141G1,142K1,143T
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ATP binding site c...1,137HATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,138TATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,139SATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,140AATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,141GATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,142KATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,143TATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,144SATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,203DATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA)1,247QATP binding site
1,137H, 1,138T, 1,139S, 1,140A, 1,141G, 1,142K, 1,143T, 1,144S, 1,203D, 1,247Q
CDD
cd00009 (AAA) -
Walker B motif cd0...1,199W1,200I1,201V1,202L1,203D1,204E
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arginine finger cd...1,266R
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Walker A motif cd0...1,428G1,429E1,430T1,431G1,432C1,433G1,434K1,435T
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ATP binding site c...1,429E1,430T1,431G1,432C1,433G1,434K1,435T1,436T
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Walker A motif cd0...1,829G1,830S1,831P1,832G1,833V1,834G1,835K1,836T
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ATP binding site c...1,830SATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,831PATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,832GATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,833VATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,834GATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,835KATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,836TATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,837SATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,899DATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA)1,944NATP binding site
1,830S, 1,831P, 1,832G, 1,833V, 1,834G, 1,835K, 1,836T, 1,837S, 1,899D, 1,944N
CDD
cd00009 (AAA) -
Walker B motif cd0...1,895W1,896V1,897L1,898L1,899D1,900E
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arginine finger cd...1,958S
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metal ion dependen...5,252Dmetal ion dependent adhesion site (MIDAS)
5,252D, 5,254S, 5,256S, 5,323T, 5,358D
CDD
cd01460 (vWA_midasin)5,254Smetal ion dependent adhesion site (MIDAS)
5,252D, 5,254S, 5,256S, 5,323T, 5,358D
CDD
cd01460 (vWA_midasin)5,256Smetal ion dependent adhesion site (MIDAS)
5,252D, 5,254S, 5,256S, 5,323T, 5,358D
CDD
cd01460 (vWA_midasin)5,323Tmetal ion dependent adhesion site (MIDAS)
5,252D, 5,254S, 5,256S, 5,323T, 5,358D
CDD
cd01460 (vWA_midasin)5,358Dmetal ion dependent adhesion site (MIDAS)
5,252D, 5,254S, 5,256S, 5,323T, 5,358D
CDD
cd01460 (vWA_midasin)
GO term prediction
Biological Process
GO:0000027 ribosomal large subunit assembly
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATPase activity
Cellular Component
GO:0005634 nucleus