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Entry type
Status
Per-residue features
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Protein
GBC27576.1
Length
768 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain87 - 197
- Aspartic peptidase domain (IPR021109)
- Retroviral aspartyl protease (IPR013242)
374 - 553- Reverse transcriptase domain (IPR000477)
- Aspartic peptidase domain (IPR021109)
1
100
200
300
400
500
600
700
768
Detailed signature matches
no IPR
Unintegrated signatures
-
224 - 256
-
SSF56672 (DNA/RNA p...)319 - 750
-
cd00303 (retropepsi...)104 - 181
-
cd01647 (RT_LTR)377 - 553
-
cd09274 (RNase_HI_R...)647 - 766
-
mobidb-lite (disord...)224 - 258
Residue annotation
-
Catalytic residue ...105D
-
catalytic motif cd...
-
inhibitor binding ...105D107G109A133M134V135N174I
-
Active site flap c...133M134V135N136V140R141R142R143P
-
putative NTP bindi...440D441L442A443S444G445F474F504D
-
putative active si...440Dputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)441Lputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)442Aputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)443Sputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)444Gputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)445Fputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)474Fputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)475Gputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)502Yputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)504Dputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)505Dputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)549Lputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR)550Gputative active site
440D, 441L, 442A, 443S, 444G, 445F, 474F, 475G, 502Y, 504D, 505D, 549L, 550G
CDD
cd01647 (RT_LTR) -
putative nucleic a...475G
-
active site cd09274
-
RNA/DNA hybrid bin...651DRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)652ARNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)653SRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)654TRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)688SRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)689IRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)690TRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)693ERNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)718DRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)751NRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)765RRNA/DNA hybrid binding site
651D, 652A, 653S, 654T, 688S, 689I, 690T, 693E, 718D, 751N, 765R
CDD
cd09274 (RNase_HI_RT_Ty3)
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.