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Protein

GBC27480.1

Length

1,040 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
246 - 346
C2 domain (IPR000008)
399 - 421
C2 domain (IPR000008)
449 - 498
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (IPR002219)
515 - 565
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (IPR002219)
720 - 1,023
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
Domain
983 - 1,040
AGC-kinase, C-terminal (IPR000961)
Protein kinase, C-terminal (IPR017892)
Repeat
6 - 69
HR1 rho-binding repeat (IPR011072)
152 - 224
HR1 rho-binding repeat (IPR011072)

1 100 200 300 400 500 600 700 800 900 1040

Detailed signature matches

IPR000008

C2 domain

PS50004 (C2)

247 - 331

PROSITE profiles
PS50004 (C2)
SSF49562 (C2 domain...)

246 - 339

SUPERFAMILY
SSF49562 (C2 domain (Calcium/lipid-binding domain, CaLB))

399 - 421

SUPERFAMILY
SSF49562 (C2 domain (Calcium/lipid-binding domain, CaLB))
SM00239 (C2_3c)

250 - 346

SMART
SM00239 (C2_3c)
PF00168 (C2)

249 - 341

Pfam
PF00168 (C2)

IPR002219

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain

SM00109 (c1_12)

450 - 496

SMART
SM00109 (c1_12)

516 - 565

SMART
SM00109 (c1_12)
PF00130 (C1_1)

450 - 498

Pfam
PF00130 (C1_1)
PS00479 (ZF_DAG_PE_1)

516 - 565

PROSITE patterns
PS00479 (ZF_DAG_PE_1)
PS50081 (ZF_DAG_PE_2)

515 - 565

PROSITE profiles
PS50081 (ZF_DAG_PE_2)

449 - 496

PROSITE profiles
PS50081 (ZF_DAG_PE_2)
cd00029 (C1)

450 - 496

CDD
cd00029 (C1)

516 - 565

CDD
cd00029 (C1)

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

720 - 1,023

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

IPR000719

Protein kinase domain

SM00220 (serkin_6)

723 - 982

SMART
SM00220 (serkin_6)
PS50011 (PROTEIN_KI...)

723 - 982

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)
PF00069 (Pkinase)

725 - 982

Pfam
PF00069 (Pkinase)

IPR000961

AGC-kinase, C-terminal

SM00133 (pkinase_C_6)

983 - 1,039

SMART
SM00133 (pkinase_C_6)
PS51285 (AGC_KINASE...)

983 - 1,040

PROSITE profiles
PS51285 (AGC_KINASE_CTER)

IPR017892

Protein kinase, C-terminal

PF00433 (Pkinase_C)

1,003 - 1,019

Pfam
PF00433 (Pkinase_C)

IPR011072

HR1 rho-binding repeat

PF02185 (HR1)

158 - 219

Pfam
PF02185 (HR1)

7 - 68

Pfam
PF02185 (HR1)
SSF46585 (HR1 repeat)

152 - 219

SUPERFAMILY
SSF46585 (HR1 repeat)
SM00742 (hr1_7)

156 - 224

SMART
SM00742 (hr1_7)

6 - 69

SMART
SM00742 (hr1_7)

IPR017441

Protein kinase, ATP binding site

PS00107 (PROTEIN_KI...)

729 - 752

PROSITE patterns
PS00107 (PROTEIN_KINASE_ATP)

IPR008271

Serine/threonine-protein kinase, active site

PS00108 (PROTEIN_KI...)

844 - 856

PROSITE patterns
PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

Coil

45 - 65

COILS
Coil (Coil)
SSF57889 (Cysteine-...)

510 - 570

SUPERFAMILY
SSF57889 (Cysteine-rich domain)

441 - 498

SUPERFAMILY
SSF57889 (Cysteine-rich domain)
cd05570 (STKc_PKC)

727 - 1,019

CDD
cd05570 (STKc_PKC)
mobidb-lite (disord...)

591 - 711

MobiDB Lite
mobidb-lite (disorder_prediction)

95 - 131

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

zinc binding sites...

450H

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

463C

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

466C

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

477C

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

480C

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

485H

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

488C

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)

496C

zinc binding sites
450H, 463C, 466C, 477C, 480C, 485H, 488C, 496C
CDD
cd00029 (C1)
putative DAG/PE bi...

457F

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)

460V

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)

461M

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)

470F

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)

471V

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)

472N

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)

473E

putative DAG/PE binding site
457F, 460V, 461M, 470F, 471V, 472N, 473E
CDD
cd00029 (C1)
putative RAS inter...

460V

putative RAS interaction site
460V, 462K
CDD
cd00029 (C1)

462K

putative RAS interaction site
460V, 462K
CDD
cd00029 (C1)
zinc binding sites...

516H

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

529C

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

532C

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

546C

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

549C

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

554H

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

557C

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)

565C

zinc binding sites
516H, 529C, 532C, 546C, 549C, 554H, 557C, 565C
CDD
cd00029 (C1)
putative DAG/PE bi...

523N

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

526A

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

527N

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

536L

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

537P

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

538L

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

539V

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

540K

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

541K

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)

542G

putative DAG/PE binding site
523N, 526A, 527N, 536L, 537P, 538L, 539V, 540K, 541K, 542G
CDD
cd00029 (C1)
putative RAS inter...

526A

putative RAS interaction site
526A, 528W
CDD
cd00029 (C1)

528W

putative RAS interaction site
526A, 528W
CDD
cd00029 (C1)
ATP binding site c...

729L

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

730G

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

731K

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

732G

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

733N

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

737V

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

750A

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

752K

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

787L

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

804E

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

805Y

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

806V

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

810D

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

848D

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

850K

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

852D

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

853N

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

855L

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

865A

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)

866D

ATP binding site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 804E, 805Y, 806V, 810D, 848D, 850K, 852D, 853N, 855L, 865A, 866D
CDD
cd05570 (STKc_PKC)
active site cd05570

729L

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

730G

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

731K

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

732G

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

733N

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

737V

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

750A

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

752K

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

787L

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

803M

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

804E

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

806V

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

810D

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

812M

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

848D

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

850K

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

852D

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

853N

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

855L

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

865A

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

866D

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

869L

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

883F

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

884C

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

885G

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

886T

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

887P

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

888E

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

915E

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

921S

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

924R

active site
729L, 730G, 731K, 732G, 733N, 737V, 750A, 752K, 787L, 803M, 804E, 806V, 810D, 812M, 848D, 850K, 852D, 853N, 855L, 865A, 866D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)
polypeptide substr...

733N

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

810D

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

812M

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

848D

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

850K

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

852D

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

869L

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

883F

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

884C

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

885G

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

886T

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

887P

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

888E

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

915E

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

921S

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)

924R

polypeptide substrate binding site
733N, 810D, 812M, 848D, 850K, 852D, 869L, 883F, 884C, 885G, 886T, 887P, 888E, 915E, 921S, 924R
CDD
cd05570 (STKc_PKC)
activation loop (A...

865A

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

866D

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

867Y

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

868G

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

869L

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

870C

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

871K

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

872E

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

873E

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

874M

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

875W

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

876W

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

877G

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

879T

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

880T

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

881N

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

882T

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

883F

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

884C

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

885G

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

886T

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

887P

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

888E

activation loop (A-loop)
865A, 866D, 867Y, 868G, 869L, 870C, 871K, 872E, 873E, 874M, 875W, 876W, 877G, 879T, 880T, 881N, 882T, 883F, 884C, 885G, 886T, 887P, 888E
CDD
cd05570 (STKc_PKC)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component