GBC26477.1

Protein

Length

1,176 amino acids

Protein family membership

Arf GTPase activating protein (IPR001164)

Domains and repeats

Domain
284 - 516
Arfaptin homology (AH) domain/BAR domain (IPR027267)
589 - 623
Arfaptin homology (AH) domain/BAR domain (IPR027267)
Domain
591 - 699
PH domain-like (IPR011993)
Pleckstrin homology domain (IPR001849)

1 200 400 600 800 1000 1176

Detailed signature matches

IPR001164

Arf GTPase activating protein
1. PS50115 (ARFGAP)
  
  772 - 981
  
  PROSITE profiles
  PS50115 (ARFGAP)
2. SM00105 (arf_gap_3)
  
  772 - 883
  
  SMART
  SM00105 (arf_gap_3)
3. PR00405 (REVINTRACTNG)
  
  807 - 824
  
  PRINTS
  PR00405 (REVINTRACTNG)
  
  788 - 807
  
  PRINTS
  PR00405 (REVINTRACTNG)
4. PF01412 (ArfGap)
  
  785 - 867
  
  Pfam
  PF01412 (ArfGap)
IPR027267

Arfaptin homology (AH) domain/BAR domain
1. SSF103657 (BAR/IMD ...)
  
  284 - 516
  
  SUPERFAMILY
  SSF103657 (BAR/IMD domain-like)
  
  589 - 623
  
  SUPERFAMILY
  SSF103657 (BAR/IMD domain-like)
IPR011993

PH domain-like
1. SSF50729 (PH domain...)
  
  594 - 696
  
  SUPERFAMILY
  SSF50729 (PH domain-like)
IPR001849

Pleckstrin homology domain
1. PS50003 (PH_DOMAIN)
  
  591 - 697
  
  PROSITE profiles
  PS50003 (PH_DOMAIN)
2. SM00233 (PH_update)
  
  592 - 699
  
  SMART
  SM00233 (PH_update)
3. PF00169 (PH)
  
  593 - 696
  
  Pfam
  PF00169 (PH)

no IPR

Unintegrated signatures

Coil

491 - 518

COILS
Coil (Coil)

381 - 401

COILS
Coil (Coil)
PF16746 (BAR_3)

284 - 514

Pfam
PF16746 (BAR_3)
SSF57863 (ArfGap/Re...)

787 - 865

SUPERFAMILY
SSF57863 (ArfGap/RecO-like zinc finger)
cd07608 (BAR_ArfGAP...)

291 - 491

CDD
cd07608 (BAR_ArfGAP_fungi)
mobidb-lite (disord...)

864 - 955

MobiDB Lite
mobidb-lite (disorder_prediction)

512 - 572

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

dimer interface cd...

299K

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

302S

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

303L

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

307I

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

309R

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

310V

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

313A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

314A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

318Q

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

319E

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

327T

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

328E

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

330I

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

331F

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

334T

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

335L

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

337A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

338A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

341A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

354L

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

357A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

358S

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

451Q

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

454H

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

455G

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

457R

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

463L

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

466L

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

467T

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

469F

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

470A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

473Q

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

474F

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

477Y

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

478Q

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

480T

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

481A

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

484I

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

485Q

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

487L

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

488K

dimer interface
299K, 302S, 303L, 307I, 309R, 310V, 313A, 314A, 318Q, 319E, 327T, 328E, 330I, 331F, 334T, 335L, 337A, 338A, 341A, 354L, 357A, 358S, 451Q, 454H, 455G, 457R, 463L, 466L, 467T, 469F, 470A, 473Q, 474F, 477Y, 478Q, 480T, 481A, 484I, 485Q, 487L, 488K
CDD
cd07608 (BAR_ArfGAP_fungi)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005096 GTPase activator activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

GBC26477.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component