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Entry type
Status
Per-residue features
Colour by
Protein
GBC26253.1
Length
719 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
719
Detailed signature matches
no IPR
Unintegrated signatures
-
cd06614 (STKc_PAK)
-
mobidb-lite (disord...)
Residue annotation
-
GTPase interaction...
-
ATP binding site c...
-
active site cd06614558Nactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)560Lactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)570Tactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)571Dactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)574Factive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)587Tactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)588Mactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)589Vactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)590Gactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)591Tactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)593Yactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)620Eactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)629Lactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)630Nactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)631Eactive site
440I, 441G, 442Q, 443G, 444A, 448V, 461A, 463K, 492V, 508M, 509E, 510Y, 511M, 512E, 514G, 515S, 518D, 553D, 555K, 556S, 557D, 558N, 560L, 570T, 571D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK) -
polypeptide substr...443Gpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)444Apolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)553Dpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)555Kpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)556Spolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)557Dpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)574Fpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)587Tpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)588Mpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)589Vpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)590Gpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)591Tpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)593Ypolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)620Epolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)629Lpolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)630Npolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK)631Epolypeptide substrate binding site
443G, 444A, 553D, 555K, 556S, 557D, 574F, 587T, 588M, 589V, 590G, 591T, 593Y, 620E, 629L, 630N, 631E
CDD
cd06614 (STKc_PAK) -
activation loop (A...570Tactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)571Dactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)572Factivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)573Gactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)574Factivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)575Cactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)576Aactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)577Qactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)578Iactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)579Nactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)580Eactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)581Hactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)586Tactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)587Tactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)588Mactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)589Vactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)590Gactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)591Tactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)592Pactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)593Yactivation loop (A-loop)
570T, 571D, 572F, 573G, 574F, 575C, 576A, 577Q, 578I, 579N, 580E, 581H, 586T, 587T, 588M, 589V, 590G, 591T, 592P, 593Y
CDD
cd06614 (STKc_PAK)
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.