GBC24944.1

Protein

Length

679 amino acids

Protein family membership

Small GTPase superfamily (IPR001806)
- Small GTPase superfamily, Rho type (IPR003578)

Domains and repeats

Domain
1 - 173
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Small GTP-binding protein domain (IPR005225)
334 - 615
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
Serine-threonine/tyrosine-protein kinase, catalytic domain (IPR001245)

1 100 200 300 400 500 600 679

Detailed signature matches

IPR001806

Small GTPase superfamily
1. PF00071 (Ras)
  
  5 - 175
  
  Pfam
  PF00071 (Ras)
IPR003578

Small GTPase superfamily, Rho type
1. PS51420 (RHO)
  
  1 - 176
  
  PROSITE profiles
  PS51420 (RHO)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  4 - 173
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR005225

Small GTP-binding protein domain
1. TIGR00231
  
  1 - 157
  
  TIGRFAMs
  TIGR00231 (TIGR00231)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  334 - 606
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  351 - 615
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
IPR001245

Serine-threonine/tyrosine-protein kinase, catalytic domain
1. PF07714 (Pkinase_Tyr)
  
  354 - 606
  
  Pfam
  PF07714 (Pkinase_Tyr)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  357 - 379
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)

no IPR

Unintegrated signatures

PR00449 (RASTRNSFRMNG)

154 - 176

PRINTS
PR00449 (RASTRNSFRMNG)

27 - 43

PRINTS
PR00449 (RASTRNSFRMNG)

44 - 66

PRINTS
PR00449 (RASTRNSFRMNG)

106 - 119

PRINTS
PR00449 (RASTRNSFRMNG)

4 - 25

PRINTS
PR00449 (RASTRNSFRMNG)
SM00173 (ras_sub_4)

1 - 179

SMART
SM00173 (ras_sub_4)
SM00174 (rho_sub_3)

6 - 179

SMART
SM00174 (rho_sub_3)
SM00175 (rab_sub_5)

4 - 179

SMART
SM00175 (rab_sub_5)
cd01874 (Cdc42)

3 - 177

CDD
cd01874 (Cdc42)

Residue annotation

GEF (guanine nucle...

3S

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

5K

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

31E

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

32F

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

35T

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

36V

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

38D

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

39N

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

41A

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

43T

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

52T

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

56F

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

57D

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

58M

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

59T

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

60G

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

61Q

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

64Y

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

65D

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

66R

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

67L

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

70L

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

71S

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

73A

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

74Q

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

103H

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)

104H

GEF (guanine nucleotide exchange factor) interaction site
3S, 5K, 31E, 32F, 35T, 36V, 38D, 39N, 41A, 43T, 52T, 56F, 57D, 58M, 59T, 60G, 61Q, 64Y, 65D, 66R, 67L, 70L, 71S, 73A, 74Q, 103H, 104H
CDD
cd01874 (Cdc42)
ACK tyrosine kinas...

4I

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

7V

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

8L

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

9V

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

10G

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

11D

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

12E

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

13N

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

16K

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

20L

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

21I

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

23Y

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

28F

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

30S

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

31E

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

32F

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

33V

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

34P

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

35T

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

36V

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

37F

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

38D

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

39N

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

40Y

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

41A

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

42V

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

43T

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

44I

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

45M

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

46I

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

47G

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

48D

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

52T

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

53L

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

57D

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

58M

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

59T

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

60G

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

61Q

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

62E

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

63D

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

67L

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

68R

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

70L

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

116Q

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

120R

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

166K

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

170D

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

173I

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

174V

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

177L

ACK tyrosine kinase interaction site
4I, 7V, 8L, 9V, 10G, 11D, 12E, 13N, 16K, 20L, 21I, 23Y, 28F, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y, 41A, 42V, 43T, 44I, 45M, 46I, 47G, 48D, 52T, 53L, 57D, 58M, 59T, 60G, 61Q, 62E, 63D, 67L, 68R, 70L, 116Q, 120R, 166K, 170D, 173I, 174V, 177L
CDD
cd01874 (Cdc42)
G1 box cd01874

10G

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

11D

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

12E

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

13N

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

14A

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

15E

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

16K

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)

17T

G1 box
10G, 11D, 12E, 13N, 14A, 15E, 16K, 17T
CDD
cd01874 (Cdc42)
GTP/Mg2+ binding s...

13N

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

14A

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

15E

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

16K

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

17T

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

18T

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

29P

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

32F

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

33V

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

35T

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

57D

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

58M

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

60G

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

116Q

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

118D

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

159A

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)

160L

GTP/Mg2+ binding site
13N, 14A, 15E, 16K, 17T, 18T, 29P, 32F, 33V, 35T, 57D, 58M, 60G, 116Q, 118D, 159A, 160L
CDD
cd01874 (Cdc42)
CRIB effector inte...

20L

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

21I

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

36V

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

38D

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

40Y

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

46I

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

67L

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

70L

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

173I

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

174V

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)

177L

CRIB effector interaction site
20L, 21I, 36V, 38D, 40Y, 46I, 67L, 70L, 173I, 174V, 177L
CDD
cd01874 (Cdc42)
Par6 cell polarity...

23Y

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

24T

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

25T

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

37F

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

39N

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

40Y

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

41A

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

43T

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

45M

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

46I

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

47G

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

64Y

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)

166K

Par6 cell polarity protein interaction site
23Y, 24T, 25T, 37F, 39N, 40Y, 41A, 43T, 45M, 46I, 47G, 64Y, 166K
CDD
cd01874 (Cdc42)
Switch I region cd...

25T

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

26N

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

27K

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

28F

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

29P

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

30S

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

31E

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

32F

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

33V

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

34P

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

35T

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

36V

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

37F

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

38D

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

39N

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)

40Y

Switch I region
25T, 26N, 27K, 28F, 29P, 30S, 31E, 32F, 33V, 34P, 35T, 36V, 37F, 38D, 39N, 40Y
CDD
cd01874 (Cdc42)
GAP (GTPase-activa...

32F

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

34P

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

36V

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

37F

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

61Q

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

62E

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

63D

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

64Y

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

67L

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)

70L

GAP (GTPase-activating protein) interaction site
32F, 34P, 36V, 37F, 61Q, 62E, 63D, 64Y, 67L, 70L
CDD
cd01874 (Cdc42)
G2 box cd01874

35T

G2 box
35T
CDD
cd01874 (Cdc42)
GDI (guanine nucle...

35T

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

36V

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

59T

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

64Y

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

66R

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

67L

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

69P

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

70L

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

73A

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

103H

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

104H

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)

106P

GDI (guanine nucleotide dissociation inhibitor) interaction site
35T, 36V, 59T, 64Y, 66R, 67L, 69P, 70L, 73A, 103H, 104H, 106P
CDD
cd01874 (Cdc42)
G3 box cd01874

57D

G3 box
57D, 58M, 59T, 60G
CDD
cd01874 (Cdc42)

58M

G3 box
57D, 58M, 59T, 60G
CDD
cd01874 (Cdc42)

59T

G3 box
57D, 58M, 59T, 60G
CDD
cd01874 (Cdc42)

60G

G3 box
57D, 58M, 59T, 60G
CDD
cd01874 (Cdc42)
Switch II region c...

59T

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

60G

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

61Q

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

62E

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

63D

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

64Y

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

65D

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

66R

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

67L

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

68R

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

69P

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

70L

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

71S

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

72Y

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

73A

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

74Q

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

75T

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

76D

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)

77V

Switch II region
59T, 60G, 61Q, 62E, 63D, 64Y, 65D, 66R, 67L, 68R, 69P, 70L, 71S, 72Y, 73A, 74Q, 75T, 76D, 77V
CDD
cd01874 (Cdc42)
G4 box cd01874

115T

G4 box
115T, 116Q, 117I, 118D
CDD
cd01874 (Cdc42)

116Q

G4 box
115T, 116Q, 117I, 118D
CDD
cd01874 (Cdc42)

117I

G4 box
115T, 116Q, 117I, 118D
CDD
cd01874 (Cdc42)

118D

G4 box
115T, 116Q, 117I, 118D
CDD
cd01874 (Cdc42)
G5 box cd01874

158S

G5 box
158S, 159A, 160L
CDD
cd01874 (Cdc42)

159A

G5 box
158S, 159A, 160L
CDD
cd01874 (Cdc42)

160L

G5 box
158S, 159A, 160L
CDD
cd01874 (Cdc42)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0003924 GTPase activity
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular

Filter view on

Entry type

Status

Per-residue features