Filter view on
Entry type
Status
Per-residue features
Colour by
Protein
GBC24107.1
Length
634 amino acids
Protein family membership
- Small GTPase superfamily (IPR001806)
- Mitochondrial Rho GTPase (IPR021181)
Domains and repeats
-
Domain
-
Domain2 - 204
- P-loop containing nucleoside triphosphate hydrolase (IPR027417)
- Small GTP-binding protein domain (IPR005225)
221 - 307- EF hand associated, type-2 (IPR013567)
343 - 410- EF hand associated, type-1 (IPR013566)
413 - 576 - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
-
Domain170 - 270
- EF-hand domain pair (IPR011992)
- EF-hand domain (IPR002048)
306 - 371- EF-hand domain pair (IPR011992)
- EF-hand domain (IPR002048)
- EF-hand domain pair (IPR011992)
1
100
200
300
400
500
634
Detailed signature matches
-
-
PIRSF037488 (Miro)1 - 624
-

Unintegrated signatures
Residue annotation
-
putative GEF (guan...6Rputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)35Hputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)36Vputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)38Pputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)39Eputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)41Tputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)43Pputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)52Tputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)56Vputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)57Dputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)59Sputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)60Aputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)61Rputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)68Lputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1)71Eputative GEF (guanine nucleotide exchange factor) interaction site
6R, 35H, 36V, 38P, 39E, 41T, 43P, 52T, 56V, 57D, 59S, 60A, 61R, 68L, 71E
CDD
cd01893 (Miro1) -
G1 box cd0189311G12D13D14G15V16G17K18S
-
GTP/Mg2+ binding s...14GGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)15VGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)16GGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)17KGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)18SGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)19TGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)57DGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)58SGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)60AGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)116KGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)118DGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)151AGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1)152KGTP/Mg2+ binding site
14G, 15V, 16G, 17K, 18S, 19T, 57D, 58S, 60A, 116K, 118D, 151A, 152K
CDD
cd01893 (Miro1) -
Switch I region cd...34Q35H36V37V38P39E40V
-
G2 box cd0189335H
-
putative GAP (GTPa...36V37V61R68L
-
putative GDI (guan...36Vputative GDI (guanine nucleotide dissociation inhibitor) interaction
36V, 59S, 68L, 70T
CDD
cd01893 (Miro1)59Sputative GDI (guanine nucleotide dissociation inhibitor) interaction
36V, 59S, 68L, 70T
CDD
cd01893 (Miro1)68Lputative GDI (guanine nucleotide dissociation inhibitor) interaction
36V, 59S, 68L, 70T
CDD
cd01893 (Miro1)70Tputative GDI (guanine nucleotide dissociation inhibitor) interaction
36V, 59S, 68L, 70T
CDD
cd01893 (Miro1) -
putative effector ...37V38P68L71E
-
G3 box cd01893
-
Switch II region c...60A61R68L69K70T71E75A76N77V
-
G4 box cd01893
-
G5 box cd01893
-
G1 box cd01892423G424A425A426G427S428G429K430T
-
GTP/Mg2+ binding s...426GGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)427SGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)428GGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)429KGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)430TGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)431SGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)470QGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)471EGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)473GGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)528KGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)530DGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)559VGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2)560KGTP/Mg2+ binding site
426G, 427S, 428G, 429K, 430T, 431S, 470Q, 471E, 473G, 528K, 530D, 559V, 560K
CDD
cd01892 (Miro2) -
Switch I region cd...445Y446T447P448T449T450R451P452F453C
-
G2 box cd01892446T
-
G3 box cd01892
-
Switch II region c...472FSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)473GSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)474SSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)475KSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)476YSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)477ESwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)478ASwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)480ISwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)481LSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)482QSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)483NSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)484KSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)490CSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)491DSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2)492LSwitch II region
472F, 473G, 474S, 475K, 476Y, 477E, 478A, 480I, 481L, 482Q, 483N, 484K, 490C, 491D, 492L
CDD
cd01892 (Miro2) -
G4 box cd01892
-
G5 box cd01892
GO term prediction
Biological Process
GO:0007005 mitochondrion organization
GO:0007264 small GTPase mediated signal transduction
Molecular Function
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005525 GTP binding
Cellular Component
GO:0005739 mitochondrion
GO:0031307 integral component of mitochondrial outer membrane