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Protein

GBC23621.1

Length

620 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain

1 100 200 300 400 500 620

Detailed signature matches

IPR011701

Major facilitator superfamily

PF07690 (MFS_1)

IPR020846

Major facilitator superfamily domain

PS50850 (MFS)
cd06174 (MFS)
SSF103473 (MFS gene...)

no IPR

Unintegrated signatures

mobidb-lite (disord...)

Residue annotation

putative substrate...

339S

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

342L

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

343H

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

346S

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

360A

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

364S

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

368L

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

371P

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

375Y

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

423A

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

426Y

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

427A

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

430P

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

434V

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

435T

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

438P

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

447G

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

448L

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

451L

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

452K

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

455D

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

456N

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

459A

putative substrate translocation pore
120S, 123I, 124G, 125P, 127K, 128G, 145V, 148L, 149T, 152N, 156P, 157I, 159S, 160G, 209L, 210A, 213T, 214I, 217E, 218T, 221V, 233L, 234A, 237L, 238T, 244S, 335G, 338M, 339S, 342L, 343H, 346S, 360A, 364S, 368L, 371P, 375Y, 423A, 426Y, 427A, 430P, 434V, 435T, 438P, 447G, 448L, 451L, 452K, 455D, 456N, 459A
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

GBC23621.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component