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Entry type
Status
Per-residue features
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Protein
GBC22346.1
Length
1,952 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain667 - 768
- Retrotransposon gag domain (IPR005162)
1,118 - 1,215- Aspartic peptidase domain (IPR021109)
1,344 - 1,523- Reverse transcriptase domain (IPR000477)
1,743 - 1,946
1
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600
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1000
1200
1400
1600
1800
1952
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
Catalytic residue ...1,131D
-
catalytic motif cd...
-
inhibitor binding ...1,131Dinhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like)1,133Ginhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like)1,135Ainhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like)1,159Cinhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like)1,160Tinhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like)1,161Iinhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like)1,200Iinhibitor binding site
1,131D, 1,133G, 1,135A, 1,159C, 1,160T, 1,161I, 1,200I
CDD
cd00303 (retropepsin_like) -
Active site flap c...1,159CActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,160TActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,161IActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,162AActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,166KActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,167IActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,168AActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like)1,169AActive site flap
1,159C, 1,160T, 1,161I, 1,162A, 1,166K, 1,167I, 1,168A, 1,169A
CDD
cd00303 (retropepsin_like) -
putative NTP bindi...1,410Dputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,411Lputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,412Aputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,413Aputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,414Gputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,415Fputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,444Fputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR)1,474Dputative NTP binding site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,474D
CDD
cd01647 (RT_LTR) -
putative active si...1,410Dputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,411Lputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,412Aputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,413Aputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,414Gputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,415Fputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,444Fputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,445Gputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,472Yputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,474Dputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,475Dputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,519Lputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR)1,520Gputative active site
1,410D, 1,411L, 1,412A, 1,413A, 1,414G, 1,415F, 1,444F, 1,445G, 1,472Y, 1,474D, 1,475D, 1,519L, 1,520G
CDD
cd01647 (RT_LTR) -
putative nucleic a...1,445G
-
active site cd092741,621D1,663E1,688D1,731D
-
RNA/DNA hybrid bin...1,621DRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,622ARNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,623SRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,624GRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,658PRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,659IRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,660TRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,663ERNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,688DRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,721HRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)1,735RRNA/DNA hybrid binding site
1,621D, 1,622A, 1,623S, 1,624G, 1,658P, 1,659I, 1,660T, 1,663E, 1,688D, 1,721H, 1,735R
CDD
cd09274 (RNase_HI_RT_Ty3)
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Cellular Component
None predicted.