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Protein

GBC21003.1

Length

697 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
65 - 471
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 100 200 300 400 500 600 697

Detailed signature matches

IPR011009

Protein kinase-like domain

SSF56112 (Protein k...)

65 - 265

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

302 - 471

SUPERFAMILY
SSF56112 (Protein kinase-like (PK-like))

IPR000719

Protein kinase domain

SM00220 (serkin_6)

69 - 381

SMART
SM00220 (serkin_6)
PS50011 (PROTEIN_KI...)

69 - 381

PROSITE profiles
PS50011 (PROTEIN_KINASE_DOM)
PF00069 (Pkinase)

69 - 261

Pfam
PF00069 (Pkinase)

301 - 380

Pfam
PF00069 (Pkinase)

IPR017441

Protein kinase, ATP binding site

PS00107 (PROTEIN_KI...)

75 - 98

PROSITE patterns
PS00107 (PROTEIN_KINASE_ATP)

IPR008271

Serine/threonine-protein kinase, active site

PS00108 (PROTEIN_KI...)

198 - 210

PROSITE patterns
PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

cd14008 (STKc_LKB1_...)

75 - 381

CDD
cd14008 (STKc_LKB1_CaMKK)
mobidb-lite (disord...)

1 - 22

MobiDB Lite
mobidb-lite (disorder_prediction)

662 - 697

MobiDB Lite
mobidb-lite (disorder_prediction)

521 - 547

MobiDB Lite
mobidb-lite (disorder_prediction)

438 - 485

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

75L

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

76G

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

77R

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

78G

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

79V

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

83V

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

96A

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

98K

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

137V

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

155I

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

156E

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

157Y

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

158M

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

162E

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

202D

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

204K

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

206A

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

207N

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

209L

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)

220D

ATP binding site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 202D, 204K, 206A, 207N, 209L, 220D
CDD
cd14008 (STKc_LKB1_CaMKK)
active site cd14008

75L

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

76G

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

77R

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

78G

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

79V

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

83V

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

96A

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

98K

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

137V

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

155I

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

156E

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

157Y

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

158M

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

162E

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

164Q

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

202D

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

204K

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

206A

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

207N

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

209L

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

220D

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

223V

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

251G

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

252S

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

253P

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

254A

active site
75L, 76G, 77R, 78G, 79V, 83V, 96A, 98K, 137V, 155I, 156E, 157Y, 158M, 162E, 164Q, 202D, 204K, 206A, 207N, 209L, 220D, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)
polypeptide substr...

79V

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

162E

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

164Q

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

202D

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

204K

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

206A

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

223V

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

251G

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

252S

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

253P

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

254A

polypeptide substrate binding site
79V, 162E, 164Q, 202D, 204K, 206A, 223V, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)
activation loop (A...

219S

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

220D

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

221F

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

222G

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

223V

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

224S

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

225H

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

226F

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

239I

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

240N

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

248K

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

249T

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

250A

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

251G

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

252S

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

253P

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

254A

activation loop (A-loop)
219S, 220D, 221F, 222G, 223V, 224S, 225H, 226F, 239I, 240N, 248K, 249T, 250A, 251G, 252S, 253P, 254A
CDD
cd14008 (STKc_LKB1_CaMKK)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

GBC21003.1

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component