Filter view on
Entry type
Status
Per-residue features
Colour by
Protein
GBC19641.1
Length
340 amino acids
Protein family membership
- L-lactate/malate dehydrogenase (IPR001557)
- Malate dehydrogenase, type 1 (IPR010097)
Domains and repeats
-
Domain3 - 155
- NAD(P)-binding domain (IPR016040)
- Lactate/malate dehydrogenase, N-terminal (IPR001236)
156 - 334 - NAD(P)-binding domain (IPR016040)
1
50
100
150
200
250
300
340
Detailed signature matches
-
-
PIRSF000102 (Lac_ma...)1 - 334
-
Residue annotation
-
NAD binding site c...10ANAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)11GNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)12GNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)13INAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)34DNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)86PNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)88GNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)89VNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)100LNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)104NNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)107INAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)127INAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)129NNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)156VNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)159LNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)187HNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)234ANAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)238MNAD binding site
10A, 11G, 12G, 13I, 34D, 86P, 88G, 89V, 100L, 104N, 107I, 127I, 129N, 156V, 159L, 187H, 234A, 238M
CDD
cd01337 (MDH_glyoxysomal_mitochondrial) -
dimerization inter...15Qdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)43Adimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)44Ddimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)46Sdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)47Hdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)48Idimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)162Vdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)163Rdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)166Tdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)220Gdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)223Edimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)227Adimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)228Kdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)234Adimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)235Tdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)236Ldimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)237Sdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial)240Qdimerization interface
15Q, 43A, 44D, 46S, 47H, 48I, 162V, 163R, 166T, 220G, 223E, 227A, 228K, 234A, 235T, 236L, 237S, 240Q
CDD
cd01337 (MDH_glyoxysomal_mitochondrial) -
Substrate binding ...91R97R129N163R187H221G
GO term prediction
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006108 malate metabolic process
GO:0019752 carboxylic acid metabolic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060 L-malate dehydrogenase activity
Cellular Component
None predicted.