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Entry type
Status
Per-residue features
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Protein
GBC18890.1
Length
838 amino acids
Protein family membership
None predicted.
Domains and repeats
-
Domain4 - 101
- Aspartic peptidase domain (IPR021109)
230 - 409- Reverse transcriptase domain (IPR000477)
630 - 832
1
100
200
300
400
500
600
700
838
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
Catalytic residue ...17D
-
catalytic motif cd...
-
inhibitor binding ...17D19G21A45C46T47I86I
-
Active site flap c...45C46T47I48A52K53I54A55A
-
putative NTP bindi...296D297L298A299A300G301F330F360D
-
putative active si...296Dputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)297Lputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)298Aputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)299Aputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)300Gputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)301Fputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)330Fputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)331Gputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)358Yputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)360Dputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)361Dputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)405Lputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR)406Gputative active site
296D, 297L, 298A, 299A, 300G, 301F, 330F, 331G, 358Y, 360D, 361D, 405L, 406G
CDD
cd01647 (RT_LTR) -
putative nucleic a...331G
-
active site cd09274
-
RNA/DNA hybrid bin...507DRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)508ARNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)509SRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)510GRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)544PRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)545IRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)546TRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)549ERNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)574DRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)607HRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)621RRNA/DNA hybrid binding site
507D, 508A, 509S, 510G, 544P, 545I, 546T, 549E, 574D, 607H, 621R
CDD
cd09274 (RNase_HI_RT_Ty3)
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Cellular Component
None predicted.