GBC18701.1

Protein

Length

339 amino acids

Protein family membership

Galactose-1-phosphate uridyl transferase, class I (IPR001937)

Domains and repeats

Domain
4 - 183
HIT-like domain (IPR011146)
188 - 318
HIT-like domain (IPR011146)
Domain
4 - 182
Galactose-1-phosphate uridyl transferase, N-terminal (IPR005849)
193 - 260
Galactose-1-phosphate uridyl transferase, C-terminal (IPR005850)
262 - 319
Galactose-1-phosphate uridyl transferase, C-terminal (IPR005850)

1 50 100 150 200 250 300 339

Detailed signature matches

IPR001937

Galactose-1-phosphate uridyl transferase, class I
1. TIGR00209
  
  1 - 258
  
  TIGRFAMs
  TIGR00209 (TIGR00209)
IPR005849

Galactose-1-phosphate uridyl transferase, N-terminal
1. PF01087 (GalP_UDP_t...)
  
  4 - 182
  
  Pfam
  PF01087 (GalP_UDP_transf)
IPR011146

HIT-like domain
1. SSF54197 (HIT-like)
  
  188 - 318
  
  SUPERFAMILY
  SSF54197 (HIT-like)
  
  4 - 183
  
  SUPERFAMILY
  SSF54197 (HIT-like)
IPR005850

Galactose-1-phosphate uridyl transferase, C-terminal
1. PF02744 (GalP_UDP_tr_C)
  
  193 - 260
  
  Pfam
  PF02744 (GalP_UDP_tr_C)
  
  262 - 319
  
  Pfam
  PF02744 (GalP_UDP_tr_C)
IPR019779

Galactose-1-phosphate uridyl transferase, class I His-active site
1. PS00117 (GAL_P_UDP_...)
  
  157 - 174
  
  PROSITE patterns
  PS00117 (GAL_P_UDP_TRANSF_I)

no IPR

Unintegrated signatures

cd00608 (GalT)

11 - 317

CDD
cd00608 (GalT)

Residue annotation

dimer interface cd...

11H

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

12R

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

13R

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

14F

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

16P

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

20S

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

21W

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

25S

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

28R

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

31R

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

33W

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

34E

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

35G

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

53Y

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

81A

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

159N

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

162S

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

163I

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

164M

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

165G

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

167S

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

168N

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

176W

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

178T

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

180T

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

182P

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

183E

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

184E

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

195Y

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

210L

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

220R

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

234F

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

235W

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

238W

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

278H

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

291K

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

292F

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)

296Y

dimer interface
11H, 12R, 13R, 14F, 16P, 20S, 21W, 25S, 28R, 31R, 33W, 34E, 35G, 53Y, 81A, 159N, 162S, 163I, 164M, 165G, 167S, 168N, 176W, 178T, 180T, 182P, 183E, 184E, 195Y, 210L, 220R, 234F, 235W, 238W, 278H, 291K, 292F, 296Y
CDD
cd00608 (GalT)
active site cd00608

77N

active site
77N, 78D, 159N, 165G, 167S, 174Q
CDD
cd00608 (GalT)

78D

active site
77N, 78D, 159N, 165G, 167S, 174Q
CDD
cd00608 (GalT)

159N

active site
77N, 78D, 159N, 165G, 167S, 174Q
CDD
cd00608 (GalT)

165G

active site
77N, 78D, 159N, 165G, 167S, 174Q
CDD
cd00608 (GalT)

167S

active site
77N, 78D, 159N, 165G, 167S, 174Q
CDD
cd00608 (GalT)

174Q

active site
77N, 78D, 159N, 165G, 167S, 174Q
CDD
cd00608 (GalT)

GO term prediction

Biological Process

GO:0006012 galactose metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity
GO:0008270 zinc ion binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features