GBC17015.1

Protein

Length

444 amino acids

Protein family membership

Phenylalanyl-tRNA synthetase, class IIc, mitochondrial (IPR004530)

Domains and repeats

Domain
64 - 173
Phenylalanyl-tRNA synthetase (IPR002319)
228 - 337
Phenylalanyl-tRNA synthetase (IPR002319)
347 - 444
Ferrodoxin-fold anticodon-binding domain (IPR005121)
Domain
149 - 350
Aminoacyl-tRNA synthetase, class II (IPR006195)

1 50 100 150 200 250 300 350 400 444

Detailed signature matches

IPR004530

Phenylalanyl-tRNA synthetase, class IIc, mitochondrial
1. TIGR00469
  
  35 - 442
  
  TIGRFAMs
  TIGR00469 (TIGR00469)
IPR002319

Phenylalanyl-tRNA synthetase
1. PF01409 (tRNA-synt_2d)
  
  64 - 173
  
  Pfam
  PF01409 (tRNA-synt_2d)
  
  228 - 337
  
  Pfam
  PF01409 (tRNA-synt_2d)
IPR006195

Aminoacyl-tRNA synthetase, class II
1. PS50862 (AA_TRNA_LI...)
  
  149 - 350
  
  PROSITE profiles
  PS50862 (AA_TRNA_LIGASE_II)
IPR005121

Ferrodoxin-fold anticodon-binding domain
1. SSF54991 (Anticodon...)
  
  347 - 444
  
  SUPERFAMILY
  SSF54991 (Anticodon-binding domain of PheRS)
2. PF03147 (FDX-ACB)
  
  352 - 444
  
  Pfam
  PF03147 (FDX-ACB)
3. PS51447 (FDX_ACB)
  
  352 - 444
  
  PROSITE profiles
  PS51447 (FDX_ACB)
4. SM00896 (FDX_ACB_2)
  
  352 - 444
  
  SMART
  SM00896 (FDX_ACB_2)

no IPR

Unintegrated signatures

SSF55681 (Class II ...)

233 - 337

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)

58 - 180

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)
cd00496 (PheRS_alph...)

68 - 332

CDD
cd00496 (PheRS_alpha_core)

Residue annotation

dimer interface cd...

68H

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

71Y

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

74R

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

75T

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

82P

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

87F

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

88N

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

90F

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

91N

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

92P

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

108D

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

113S

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

117S

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

118Y

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

119Y

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

120I

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

121N

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

122K

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

137V

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

143T

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

144K

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

148S

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

150D

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

152Y

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

154R

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

162Y

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

231I

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

232K

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

233H

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

235K

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

236F

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

259D

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

266C

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

267P

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

268S

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

270E

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

289D

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

290Q

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

327W

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

329Q

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

330D

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)

331E

dimer interface
68H, 71Y, 74R, 75T, 82P, 87F, 88N, 90F, 91N, 92P, 108D, 113S, 117S, 118Y, 119Y, 120I, 121N, 122K, 137V, 143T, 144K, 148S, 150D, 152Y, 154R, 162Y, 231I, 232K, 233H, 235K, 236F, 259D, 266C, 267P, 268S, 270E, 289D, 290Q, 327W, 329Q, 330D, 331E
CDD
cd00496 (PheRS_alpha_core)
motif 1 cd00496

86Y

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)

87F

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)

88N

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)

89T

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)

90F

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)

91N

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)

92P

motif 1
86Y, 87F, 88N, 89T, 90F, 91N, 92P
CDD
cd00496 (PheRS_alpha_core)
active site cd00496

113S

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

114K

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

115T

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

129H

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

131S

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

134Q

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

153R

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

155D

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

160S

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

161H

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

162Y

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

165F

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

167Q

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

169E

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

262F

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

264F

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

265T

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

281E

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

282I

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

283C

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

284G

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

285C

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

286G

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

306F

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

307G

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

308L

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

309G

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

312R

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)

323I

active site
113S, 114K, 115T, 129H, 131S, 134Q, 153R, 155D, 160S, 161H, 162Y, 165F, 167Q, 169E, 262F, 264F, 265T, 281E, 282I, 283C, 284G, 285C, 286G, 306F, 307G, 308L, 309G, 312R, 323I
CDD
cd00496 (PheRS_alpha_core)
motif 2 cd00496

152Y

motif 2
152Y, 153R, 154R, 155D
CDD
cd00496 (PheRS_alpha_core)

153R

motif 2
152Y, 153R, 154R, 155D
CDD
cd00496 (PheRS_alpha_core)

154R

motif 2
152Y, 153R, 154R, 155D
CDD
cd00496 (PheRS_alpha_core)

155D

motif 2
152Y, 153R, 154R, 155D
CDD
cd00496 (PheRS_alpha_core)
motif 3 cd00496

307G

motif 3
307G, 308L, 309G, 310L, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

308L

motif 3
307G, 308L, 309G, 310L, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

309G

motif 3
307G, 308L, 309G, 310L, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

310L

motif 3
307G, 308L, 309G, 310L, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

311E

motif 3
307G, 308L, 309G, 310L, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

312R

motif 3
307G, 308L, 309G, 310L, 311E, 312R
CDD
cd00496 (PheRS_alpha_core)

GO term prediction

Biological Process

GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation

Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

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Entry type

Status

Per-residue features