GBC16089.1

Protein

Length

741 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
5 - 322
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139)
Domain
106 - 292
NAD(P)-binding domain (IPR016040)
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (IPR006140)

1 100 200 300 400 500 600 741

Detailed signature matches

IPR006139

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
1. PF00389 (2-Hacid_dh)
  
  5 - 322
  
  Pfam
  PF00389 (2-Hacid_dh)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  106 - 292
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR006140

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
1. PF02826 (2-Hacid_dh_C)
  
  113 - 291
  
  Pfam
  PF02826 (2-Hacid_dh_C)

no IPR

Unintegrated signatures

SSF52283 (Formate/g...)

3 - 135

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)
cd05301 (GDH)

3 - 315

CDD
cd05301 (GDH)

Residue annotation

dimerization inter...

9Q

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

10I

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

12P

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

54M

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

55L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

56T

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

77M

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

105D

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

106A

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

109D

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

110I

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

112V

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

113L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

116L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

120R

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

122I

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

130E

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

132G

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

134W

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

136W

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

137S

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

138P

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

139T

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

140W

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

141M

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

143G

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

144V

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

145Q

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

146L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

147T

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

165L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

166R

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

169P

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

170F

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

270E

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

271P

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

279L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

285T

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

286V

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

287V

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

288P

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

289H

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

290I

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

291G

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

293G

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

294T

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

295L

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

296E

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)

298R

dimerization interface
9Q, 10I, 12P, 54M, 55L, 56T, 77M, 105D, 106A, 109D, 110I, 112V, 113L, 116L, 120R, 122I, 130E, 132G, 134W, 136W, 137S, 138P, 139T, 140W, 141M, 143G, 144V, 145Q, 146L, 147T, 165L, 166R, 169P, 170F, 270E, 271P, 279L, 285T, 286V, 287V, 288P, 289H, 290I, 291G, 293G, 294T, 295L, 296E, 298R
CDD
cd05301 (GDH)
ligand binding sit...

55L

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

78S

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

79V

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

80G

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

103L

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

241R

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

289H

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)

292S

ligand binding site
55L, 78S, 79V, 80G, 103L, 241R, 289H, 292S
CDD
cd05301 (GDH)
NADP binding site ...

79V

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

80G

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

107V

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

155G

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

156L

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

157G

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

158R

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

159I

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

180F

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

181G

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

182R

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

185K

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

211C

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

212C

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

213A

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

217E

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

218T

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

239T

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

240A

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

241R

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

265D

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

266V

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

289H

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

291G

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)

292S

NADP binding site
79V, 80G, 107V, 155G, 156L, 157G, 158R, 159I, 180F, 181G, 182R, 185K, 211C, 212C, 213A, 217E, 218T, 239T, 240A, 241R, 265D, 266V, 289H, 291G, 292S
CDD
cd05301 (GDH)
catalytic site cd0...

241R

catalytic site
241R, 270E, 289H
CDD
cd05301 (GDH)

270E

catalytic site
241R, 270E, 289H
CDD
cd05301 (GDH)

289H

catalytic site
241R, 270E, 289H
CDD
cd05301 (GDH)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

Cellular Component