GBC15962.1

Protein

Length

454 amino acids

Protein family membership

Tubulin (IPR000217)
- Gamma tubulin (IPR002454)

Domains and repeats

Domain
2 - 247
Tubulin/FtsZ, GTPase domain (IPR003008)
249 - 393
Tubulin/FtsZ, 2-layer sandwich domain (IPR018316)
Domain
247 - 443
Tubulin/FtsZ, C-terminal (IPR008280)

1 50 100 150 200 250 300 350 400 454

Detailed signature matches

IPR000217

Tubulin
1. PR01161 (TUBULIN)
  
  96 - 107
  
  PRINTS
  PR01161 (TUBULIN)
  
  11 - 31
  
  PRINTS
  PR01161 (TUBULIN)
  
  134 - 152
  
  PRINTS
  PR01161 (TUBULIN)
  
  179 - 192
  
  PRINTS
  PR01161 (TUBULIN)
  
  52 - 71
  
  PRINTS
  PR01161 (TUBULIN)
  
  153 - 174
  
  PRINTS
  PR01161 (TUBULIN)
  
  193 - 213
  
  PRINTS
  PR01161 (TUBULIN)
  
  380 - 408
  
  PRINTS
  PR01161 (TUBULIN)
  
  108 - 132
  
  PRINTS
  PR01161 (TUBULIN)
IPR002454

Gamma tubulin
1. cd02188 (gamma_tubulin)
  
  3 - 435
  
  CDD
  cd02188 (gamma_tubulin)
2. PR01164 (GAMMATUBULIN)
  
  288 - 303
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  364 - 384
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  116 - 131
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  193 - 206
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  339 - 362
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  31 - 51
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  420 - 443
  
  PRINTS
  PR01164 (GAMMATUBULIN)
  
  251 - 262
  
  PRINTS
  PR01164 (GAMMATUBULIN)
IPR003008

Tubulin/FtsZ, GTPase domain
1. PF00091 (Tubulin)
  
  4 - 214
  
  Pfam
  PF00091 (Tubulin)
2. SSF52490 (Tubulin n...)
  
  2 - 246
  
  SUPERFAMILY
  SSF52490 (Tubulin nucleotide-binding domain-like)
3. SM00864 (Tubulin_4)
  
  48 - 247
  
  SMART
  SM00864 (Tubulin_4)
IPR008280

Tubulin/FtsZ, C-terminal
1. SSF55307 (Tubulin C...)
  
  247 - 443
  
  SUPERFAMILY
  SSF55307 (Tubulin C-terminal domain-like)
IPR018316

Tubulin/FtsZ, 2-layer sandwich domain
1. SM00865 (Tubulin_C_4)
  
  249 - 393
  
  SMART
  SM00865 (Tubulin_C_4)
2. PF03953 (Tubulin_C)
  
  264 - 391
  
  Pfam
  PF03953 (Tubulin_C)
IPR017975

Tubulin, conserved site
1. PS00227 (TUBULIN)
  
  142 - 148
  
  PROSITE patterns
  PS00227 (TUBULIN)

no IPR

Unintegrated signatures

Coil

421 - 441

COILS
Coil (Coil)

Residue annotation

oligomer interface...

3R

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

47R

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

133E

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

252D

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

254V

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

258A

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

261I

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

262P

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

264P

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

265K

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

330P

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

331T

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

333V

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

334H

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

337L

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

338L

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

341R

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

353P

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

354A

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

357Q

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

358V

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

430D

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

433N

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)

434E

oligomer interface
3R, 47R, 133E, 252D, 254V, 258A, 261I, 262P, 264P, 265K, 330P, 331T, 333V, 334H, 337L, 338L, 341R, 353P, 354A, 357Q, 358V, 430D, 433N, 434E
CDD
cd02188 (gamma_tubulin)
nucleotide binding...

11G

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

12Q

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

13C

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

16Q

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

102N

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

140S

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

142A

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

143G

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

144G

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

145T

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

146G

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

171V

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

173P

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

207N

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

225F

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

228T

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

229N

nucleotide binding site
11G, 12Q, 13C, 16Q, 102N, 140S, 142A, 143G, 144G, 145T, 146G, 171V, 173P, 207N, 225F, 228T, 229N
CDD
cd02188 (gamma_tubulin)

GO term prediction

Biological Process

GO:0007017 microtubule-based process
GO:0007020 microtubule nucleation
GO:0031122 cytoplasmic microtubule organization

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0000930 gamma-tubulin complex
GO:0005874 microtubule

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Entry type

Status

Per-residue features